CUEROX 500: Comprehensive Guide to Cefuroxime Axetil (500mg)

Jul 16, 2024

CUEROX 500 is an oral antibiotic tablet that contains Cefuroxime Axetil 500 mg. Cefuroxime Axetil is a prodrug, which means it is converted into its active form (cefuroxime) after absorption in the body. It belongs to the cephalosporin group of antibiotics and is effective against a wide range of Gram-positive and Gram-negative bacteria.

Composition of CUEROX 500

  • Active Ingredient: Cefuroxime Axetil 500 mg

  • Dosage Form: Oral tablet

CUEROX 500 is prescribed for patients who require a higher dose for moderate bacterial infections or when lower doses are insufficient.

How CUEROX 500 Works (Mechanism of Action)

Cefuroxime Axetil works by inhibiting bacterial cell wall synthesis, which is essential for bacterial survival.

Step-by-Step Action

  1. After oral intake, Cefuroxime Axetil is absorbed from the intestine and converted into active cefuroxime.

  2. Cefuroxime binds to penicillin-binding proteins (PBPs) present in bacterial cell walls.

  3. This binding disrupts the formation of the bacterial cell wall.

  4. As a result, the bacterial cell becomes weak and eventually dies.

Why This is Important

  • Kills bacteria rather than just stopping their growth

  • Effective against bacteria resistant to some older antibiotics

  • Helps prevent spread of infection

Uses of CUEROX 500

CUEROX 500 is prescribed for a wide range of bacterial infections, including:

1. Respiratory Tract Infections

  • Acute bronchitis

  • Community-acquired pneumonia

  • Tonsillitis and pharyngitis

  • Sinusitis

2. Ear, Nose, and Throat (ENT) Infections

  • Otitis media (middle ear infection)

  • Throat and sinus infections caused by bacteria

3. Urinary Tract Infections (UTIs)

  • Uncomplicated UTIs

  • Cystitis

  • Mild kidney infections caused by susceptible organisms

4. Skin and Soft Tissue Infections

  • Cellulitis

  • Skin abscesses

  • Wound infections

5. Sexually Transmitted Infections

  • Uncomplicated gonorrhea (as per physician advice)

6. Dental Infections

  • Dental abscesses

  • Post-dental procedure infections

Benefits of CUEROX 500

1. Broad-Spectrum Antibiotic Coverage

CUEROX 500 is effective against a wide range of bacteria, making it suitable for multiple infections.

2. Reliable Oral Antibiotic

Provides hospital-grade antibiotic coverage in an oral tablet form.

3. Effective in Resistant Infections

Works against bacteria resistant to first-generation antibiotics.

4. Faster Symptom Relief

Reduces fever, pain, swelling, and inflammation within a few days of treatment.

5. Well-Tolerated

Most patients tolerate CUEROX 500 well when taken as prescribed.

6. Suitable for Adults and Older Children

Used safely in adults and adolescents under medical guidance.

Dosage of CUEROX 500

Recommended Adult Dosage

  • 500 mg twice daily (every 12 hours)

  • Duration usually 5–10 days, depending on infection severity

How to Take CUEROX 500

  • Take after food to improve absorption

  • Swallow the tablet whole with water

  • Do not crush or chew the tablet

Missed Dose

  • Take as soon as remembered

  • Skip if it is almost time for the next dose

  • Do not take a double dose

Pediatric Use

  • Dosage in children depends on age and weight

  • Should only be given under medical supervision

Side Effects of CUEROX 500

CUEROX 500 is generally safe, but like all antibiotics, it may cause side effects in some individuals.

Common Side Effects

  • Nausea

  • Diarrhea

  • Abdominal discomfort

  • Headache

Less Common Side Effects

  • Vomiting

  • Skin rash

  • Dizziness

Rare but Serious Side Effects

  • Severe allergic reactions (swelling, difficulty breathing)

  • Persistent diarrhea (possible antibiotic-associated colitis)

  • Liver enzyme elevation

If any severe or unusual symptoms occur, medical attention should be sought immediately.

Precautions and Warnings

1. Allergy History

  • Avoid if allergic to cefuroxime or other cephalosporins

  • Inform doctor about penicillin allergy

2. Kidney Disorders

  • Dose adjustment may be required in kidney disease

3. Gastrointestinal Conditions

  • Use with caution in patients with a history of colitis

4. Pregnancy and Breastfeeding

  • Generally considered safe during pregnancy if prescribed

  • Small amounts may pass into breast milk; consult a doctor

5. Antibiotic Resistance

  • Complete the full course even if symptoms improve early

Drug Interactions

CUEROX 500 may interact with:

  • Antacids (reduce absorption)

  • Probenecid (increases cefuroxime levels)

  • Oral contraceptives (reduced effectiveness)

  • Blood thinners (may affect clotting parameters)

Always inform your healthcare provider about all medicines and supplements you are taking.

Lifestyle and Patient Tips While Taking CUEROX 500

  • Take the medicine at the same time daily

  • Drink plenty of fluids

  • Avoid unnecessary use of antibiotics

  • Do not share antibiotics with others

  • Avoid alcohol if it causes stomach discomfort

Why Choose CUEROX 500?

  • Clinically Proven Antibiotic for common infections

  • Broad-Spectrum Coverage against Gram-positive and Gram-negative bacteria

  • Convenient Oral Dosage

  • Trusted by Doctors in India

  • Effective in Respiratory, Urinary & Skin Infections

Storage Instructions

  • Store below 25°C

  • Protect from moisture and direct sunlight

  • Keep out of reach of children

  • Do not use expired tablets

Conclusion

CUEROX 500 (Cefuroxime Axetil 500 mg) is a reliable, broad-spectrum oral antibiotic used to treat a wide range of bacterial infections. Its proven mechanism of action, good safety profile, and effectiveness against resistant bacteria make it a preferred choice among healthcare professionals in India.

Frequently Asked Questions 

Q1. What is CUEROX 500 used for?

It is used to treat bacterial infections of the lungs, throat, ears, urinary tract, skin, and soft tissues.

Q2. Is CUEROX 500 an antibiotic?

Yes, it is a cephalosporin antibiotic.

Q3. Can CUEROX 500 be taken with food?

Yes, taking it after meals improves absorption.

Q4. How long does CUEROX 500 take to work?

Symptoms usually improve within 2–3 days, but the full course must be completed.

Q5. Can CUEROX 500 cause diarrhea?

Yes, mild diarrhea is common; severe diarrhea should be reported to a doctor.

Q6. Is CUEROX 500 safe for long-term use?

It is usually prescribed for short courses; long-term use only under medical supervision.

Q7. Can I stop taking CUEROX 500 once I feel better?

No, stopping early can cause infection recurrence and resistance.

Q8. Is CUEROX 500 suitable for elderly patients?

Yes, with dose adjustment if kidney function is reduced.

Composition Brand Name

Cefuroxime Axetil (250mg)

CUEROX 250

Cefuroxime Axetil (500mg) & Potassium clavulanate (125mg) Tab

 

CUEROX CV 500

 

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