CUEROX 500 & Cefuroxime Axetil (500mg): Uses, Dosage, Benefits and Other Information.

Apr 15, 2024

CUEROX 500, containing Cefuroxime Axetil 500 mg, is a widely trusted second-generation cephalosporin antibiotic prescribed for a broad spectrum of bacterial infections. With its high efficacy and safe profile, CUEROX 500 is particularly recommended for adults and patients with moderate to severe bacterial infections. The medicine is known for its rapid antibacterial action and strong penetration into various tissues, making it effective in treating respiratory, urinary, skin, and ENT infections.

Cefuroxime Axetil, the active ingredient, is a prodrug that converts into Cefuroxime in the body. This conversion enhances its absorption, ensuring therapeutic levels reach infection sites efficiently. This property gives CUEROX 500 a significant advantage over other antibiotics, especially in treating stubborn or complicated infections.

India’s diverse population and environmental conditions often increase the prevalence of bacterial infections. CUEROX 500 serves as a reliable solution for patients seeking prompt relief from bacterial illnesses, supporting recovery and improving overall quality of life.

CUEROX 500 is widely prescribed for community-acquired and hospital-acquired infections, offering a clinically proven solution for doctors and patients alike.

Uses of CUEROX 500 (Cefuroxime Axetil 500 mg)

CUEROX 500 is effective in managing a wide variety of bacterial infections, including:

1. Respiratory Tract Infections

  • Pneumonia

  • Bronchitis

  • Tonsillitis

  • Pharyngitis

  • Sinusitis

Cefuroxime Axetil effectively combats Streptococcus pneumoniae, Haemophilus influenzae, and other common respiratory pathogens.

2. Skin and Soft Tissue Infections

  • Cellulitis

  • Abscesses

  • Wounds and ulcers

  • Infected dermatitis

CUEROX 500 helps reduce inflammation, redness, pus, and pain, facilitating faster healing.

3. Ear, Nose, and Throat Infections

  • Otitis media

  • Chronic ear discharge infections

  • Sinus infections

Highly effective in both adults and children for ENT-related bacterial infections.

4. Urinary Tract Infections (UTI)

  • Cystitis

  • Pyelonephritis (mild to moderate)

  • Complicated UTIs

Targets E. coli, Klebsiella, and other uropathogens to clear infections rapidly.

5. Gastrointestinal Infections

  • Typhoid fever (Salmonella typhi)

  • Selected bacterial diarrhoea cases

  • Mild intra-abdominal infections (under supervision)

CUEROX 500 provides reliable therapy for typhoid and other gastrointestinal bacterial infections.

6. Bone and Joint Infections

  • Early-stage infections may be treated under specialist supervision.

7. Post-Operative Infection Prevention

  • Used pre- or post-surgery to prevent infection due to bacterial contamination.

8. Sexually Transmitted Infections

  • Effective against certain gonococcal infections in selected patients.

Benefits of CUEROX 500

1. Broad-Spectrum Antibacterial Action

CUEROX 500 is effective against a wide range of gram-positive and gram-negative bacteria.

2. Strong Respiratory Pathogen Coverage

It provides potent relief in sinusitis, pneumonia, tonsillitis, and otitis media.

3. Enhanced Absorption

Cefuroxime Axetil is converted into active Cefuroxime in the body, ensuring rapid antibacterial activity.

4. Effective in Antibiotic-Resistant Cases

Useful when first-line antibiotics fail to provide adequate relief.

5. Rapid Symptom Relief

Fever, pain, swelling, redness, and pus reduce within 48–72 hours of therapy.

6. Safe for Adults

Well-tolerated with minimal adverse effects when taken as prescribed.

7. Reliable for Typhoid and GI Infections

Effective against Salmonella typhi, providing rapid symptom relief.

8. Reduces Risk of Infection Complications

Timely antibiotic therapy with CUEROX 500 prevents infection from spreading or worsening.

9. Convenient Oral Formulation

Easy-to-swallow tablet ensures compliance and consistent dosing.

Dosage of CUEROX 500

Important: Dosage should always be determined by a registered medical practitioner based on infection type, severity, and patient health.

Adult Dosage

  • 500 mg twice daily is standard for most moderate infections.

  • Mild infections: 250 mg–500 mg twice daily

  • Moderate to severe infections: 500 mg twice daily

Respiratory Infections

  • Pneumonia: 500 mg twice daily

  • Tonsillitis, pharyngitis, sinusitis: 250–500 mg twice daily

Skin and Soft Tissue Infections

  • Mild: 250 mg twice daily

  • Moderate: 500 mg twice daily

UTIs

  • 500 mg twice daily for 7–14 days depending on severity

Typhoid Fever

  • 500 mg twice daily for 10–14 days

How to Take CUEROX 500

  • Take after meals for better absorption.

  • Swallow the tablet whole with a glass of water.

  • Maintain consistent timing between doses.

  • Complete the full prescribed course to prevent relapse.

Side Effects of CUEROX 500

CUEROX 500 is generally well-tolerated. However, some side effects may occur:

Common Side Effects

  • Nausea

  • Diarrhoea

  • Vomiting

  • Abdominal pain or bloating

  • Mild headache

Less Common Side Effects

  • Dizziness

  • Rash or mild itching

  • Fatigue

Rare but Serious Side Effects

Seek medical attention immediately if these occur:

  • Severe diarrhoea or blood in stool

  • Persistent vomiting

  • Swelling of lips, face, tongue, or throat

  • Difficulty breathing

  • Yellowing of eyes or skin

  • Severe allergic reaction

Antibiotic-Associated Diarrhoea

Disruption of gut flora may occur; maintain hydration and consult your doctor if severe.

Precautions and Warnings

1. Allergy Alert

Avoid CUEROX 500 if allergic to Cefuroxime, cephalosporins, or penicillin-class antibiotics.

2. Kidney or Liver Conditions

Dose adjustment may be necessary for patients with renal or hepatic impairment.

3. Pregnancy and Breastfeeding

Only use under medical supervision; consult your doctor before starting.

4. Complete the Course

Stopping early can cause infection relapse and antibiotic resistance.

5. Diarrhoea or Colitis History

Patients with colitis should use CUEROX 500 cautiously.

6. Drug Interactions

Inform your doctor if you take:

  • Blood thinners

  • Antacids

  • Other antibiotics

  • Probenecid

7. Alcohol Consumption

While not strictly contraindicated, alcohol may worsen gastrointestinal side effects.

8. Viral Infections

CUEROX 500 is not effective against viral illnesses such as cold, flu, or COVID-19.

9. Paediatric and Elderly Use

Safe with proper dosing; always follow medical guidance.

Conclusion

CUEROX 500, containing Cefuroxime Axetil 500 mg, is a reliable, potent, and clinically proven antibiotic suitable for a wide range of bacterial infections. With its broad-spectrum coverage, rapid absorption, and strong tissue penetration, CUEROX 500 ensures effective bacterial eradication, symptom relief, and prevention of complications.

Frequently Asked Questions (FAQs)

1. What infections does CUEROX 500 treat?

It treats respiratory infections, ENT infections, UTIs, skin infections, and typhoid fever caused by susceptible bacteria.

2. Can CUEROX 500 be used for throat infections?

Yes, it is commonly prescribed for pharyngitis and tonsillitis.

3. How quickly does Cefuroxime Axetil work?

Most patients see symptom improvement within 48–72 hours.

4. Is it safe to take during pregnancy?

It should only be taken under a doctor’s supervision.

5. Can children take CUEROX 500?

Yes, dosing should follow paediatric guidelines.

6. Can I stop the antibiotic once symptoms improve?

No, always complete the prescribed course to prevent relapse and resistance.

7. Does CUEROX 500 cause diarrhea?

Mild diarrhea is common. Severe or bloody stools require medical attention.

8. Can it be taken with antacids?

Avoid antacids within 2 hours of taking CUEROX 500 to ensure proper absorption.

9. Can I take it for viral infections?

No, CUEROX 500 is effective only against bacterial infections.

10. Is CUEROX 500 more effective than 250 mg?

CUEROX 500 provides higher therapeutic levels for moderate to severe infections and is preferred for stronger antibacterial action.

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