Carvedilol 12.5mg & CARVEDIOL 12.5 : Tablet - Steris Healthcare PVT LTD………

Introducing CARVEDIOL 12.5: Your Trusted Companion for Heart Health

CARVEDIOL 12.5, containing carvedilol 12.5 mg tablet, is a proven medication designed to help manage various cardiovascular conditions effectively. As a beta-blocker, it plays a vital role in improving heart function and controlling blood pressure, making it an essential treatment option for many patients.

Chemical Composition and Formulations of CARVEDIOL 12.5

CARVEDIOL 12.5 tablet contains 12.5 mg of carvedilol, which is a non-selective beta-adrenergic receptor blocker with alpha1-blocking activity. This dual action helps reduce heart rate and dilate blood vessels, leading to improved blood flow and decreased cardiac workload. The formulation is a film-coated tablet designed for oral administration, ensuring ease of use and consistent dosing.

The tablet is available in strength options including 3.125 mg, 6.25 mg, 12.5 mg, and 25 mg to allow individualized dosing as per patient needs.

Mechanism of Action of Carvedilol 12.5 mg Tablet

Carvedilol 12.5 mg works by blocking beta-1 and beta-2 adrenergic receptors, along with alpha-1 receptors. Beta-blockade decreases heart rate and myocardial contractility, reducing myocardial oxygen demand. Alpha-1 blockade causes vasodilation, which lowers vascular resistance and blood pressure. Together, these effects reduce strain on the heart, improve cardiac output, and control hypertension effectively.

Uses and Indications of CARVEDIOL 12.5

CARVEDIOL 12.5 is primarily used for:

• Management of hypertension (high blood pressure)

• Treatment of chronic heart failure (CHF) to improve survival and reduce symptoms

• Post-myocardial infarction (heart attack) to improve heart function and reduce mortality

• Angina pectoris (chest pain) by improving blood flow to the heart

Carvedilol 12.5 mg Dosage and Administration

The dosing of CARVEDIOL 12.5 varies by condition and patient response:

• Hypertension: Typically started at 6.25 mg twice daily; if needed, increased to 12.5 mg twice daily or up to 25 mg twice daily.

• Chronic Heart Failure: Initial dose often 3.125 mg twice daily, gradually titrated every 2 weeks to 6.25 mg, 12.5 mg, and up to 25 mg twice daily depending on tolerance and weight.

• Post-Heart Attack: Start at 6.25 mg twice daily, increasing to 12.5 mg twice daily after 3–10 days, with possible dose increments to 25 mg twice daily.

Tablets should be taken with food to reduce the risk of dizziness and orthostatic hypotension. It is crucial to follow the prescribed regimen without abrupt cessation to avoid cardiac complications.

Efficacy and Clinical Evidence Supporting Carvedilol 12.5 mg Tablet

Clinical trials have demonstrated that carvedilol significantly reduces mortality and hospitalization rates in heart failure patients, improves exercise tolerance, and controls blood pressure effectively. Its combined beta and alpha-blocking properties offer superior cardiovascular protection compared to selective beta-blockers alone. This makes CARVEDIOL 12.5 a valuable choice in managing complex cardiac conditions.

Side Effects and Safety Profile of Carvedilol 12.5

Like all medications, carvedilol 12.5 mg may cause side effects. Common side effects include:

• Dizziness or lightheadedness, especially when standing up quickly

• Fatigue or weakness

• Low blood pressure (hypotension)

• Slow heart rate (bradycardia)

• Gastrointestinal disturbances such as nausea

Serious but less common effects include bronchospasm in asthma patients, severe bradycardia, or worsening heart failure. Regular monitoring by healthcare providers is essential to manage side effects effectively.

Contraindications and Precautions with CARVEDIOL 12.5

CARVEDIOL 12.5 should not be used in patients with:

• Severe bradycardia or heart block without a pacemaker

• Cardiogenic shock or severe heart failure not stabilized

• Asthma or severe chronic obstructive pulmonary disease (COPD)

• Known hypersensitivity to carvedilol or excipients

Caution is advised when prescribing to patients with diabetes, peripheral vascular disease, or liver impairment.

Important Drug Interactions with Carvedilol 12.5 mg Tablet

Concomitant use of CARVEDIOL 12.5 with the following medications requires caution:

• Other beta-blockers or calcium channel blockers (may cause excessive heart rate reduction)

• Antihypertensive drugs (may potentiate low blood pressure)

• Oral hypoglycemics (carvedilol may mask hypoglycemia symptoms)

• CYP2D6 inhibitors like fluoxetine (may increase carvedilol levels)

Always inform your healthcare provider about all medications you are taking.

Warnings and Regulatory Status of CARVEDIOL 12.5

CARVEDIOL 12.5 is a prescription medication approved by regulatory authorities worldwide based on rigorous clinical evidence. It comes with warnings about abrupt withdrawal, which can lead to rebound hypertension or angina exacerbation. Regular follow-up and adherence to dosing schedules are emphasized for safety.

Patient Advice and Tips for Using Carvedilol 12.5 mg Tablet

• Take CARVEDIOL 12.5 exactly as prescribed by your doctor, preferably with meals.

• Do not stop taking the medication suddenly without consulting your doctor.

• Monitor blood pressure and heart rate regularly at home.

• Avoid alcohol and be cautious when standing to prevent dizziness.

• Inform your healthcare provider if you experience side effects like excessive fatigue, shortness of breath, or swelling.

Frequently Asked Questions (FAQs) about Carvedilol 12.5 mg

Q1: Can I take carvedilol 12.5 mg tablet with food?
A: Yes, taking it with food reduces dizziness and helps absorption.

Q2: What if I miss a dose?
A: Take it as soon as you remember unless it's near the time of your next dose; do not double the dose.

Q3: Can children take CARVEDIOL 12.5?
A: Safety in children under 18 is not established; use under strict medical supervision if prescribed.

Q4: How long does it take to see effects?
A: Blood pressure lowering may occur within hours, but heart failure benefits typically develop over weeks.

Why Choose Steris Healthcare Pvt Ltd for CARVEDIOL 12.5

Steris Healthcare Pvt Ltd is committed to quality and patient safety, offering CARVEDIOL 12.5 manufactured under stringent regulatory standards to ensure consistent efficacy and purity. Their products undergo thorough quality control and are backed by dedicated customer support, making them a trusted choice for healthcare professionals and patients alike.

In conclusion, carvedilol 12.5 mg is a reliable and effective medication option for managing hypertension, heart failure, and related cardiac conditions. With its proven benefits, clear dosing guidelines, and manageable safety profile, this medication continues to support patients in maintaining optimal heart health. Choosing CARVEDIOL 12.5 from Steris Healthcare Pvt Ltd means opting for a product that prioritizes your well-being with quality and care. Always consult your healthcare provider to determine if this medication is right for you and to receive personalized dosage advice.