Carbimazole 10mg

Introduction

CARBIZOLE 10 is a pharmaceutical medication containing Carbimazole (10mg), primarily used in the treatment of hyperthyroidism and Graves' disease. It belongs to the class of antithyroid drugs that work by reducing excessive thyroid hormone production in the body. This medication is essential for individuals diagnosed with an overactive thyroid gland, a condition where the thyroid gland produces an excessive amount of thyroxine (T4) and triiodothyronine (T3), leading to various metabolic disorders.

Hyperthyroidism, if left untreated, can cause serious complications such as thyroid storm, heart problems, and osteoporosis. CARBIZOLE 10 helps manage the symptoms by inhibiting thyroid hormone synthesis, ultimately restoring hormonal balance and improving the patient's overall well-being.

In this article, we will discuss the uses, dosage, benefits, side effects, precautions, and interactions of CARBIZOLE 10 to provide a detailed insight into its therapeutic importance.

Uses of CARBIZOLE 10 (Carbimazole 10mg)

CARBIZOLE 10 is prescribed for the following conditions:

1. Hyperthyroidism

Hyperthyroidism occurs when the thyroid gland becomes overactive and produces excessive hormones. CARBIZOLE 10 helps inhibit the production of thyroid hormones by blocking the conversion of iodide into active thyroid hormones.

2. Graves’ Disease

Graves' disease is an autoimmune disorder that causes the thyroid gland to become hyperactive. CARBIZOLE 10 is commonly prescribed to manage this condition, as it helps regulate thyroid hormone levels and prevents complications such as eye problems (thyroid eye disease).

3. Thyroid Storm Prevention

A thyroid storm is a life-threatening condition where an overactive thyroid leads to severe fever, rapid heart rate, and extreme agitation. CARBIZOLE 10 plays a vital role in preventing this condition in high-risk patients.

4. Pre-Surgical Thyroid Treatment

Before undergoing thyroid surgery or radioactive iodine therapy, patients with hyperthyroidism may be prescribed CARBIZOLE 10 to stabilize thyroid hormone levels and reduce the risk of complications during the procedure.

How CARBIZOLE 10 (Carbimazole 10mg) Works

CARBIZOLE 10 contains Carbimazole (10mg), which is an antithyroid medication. Once ingested, Carbimazole is converted into Methimazole, its active form, which directly inhibits the thyroid peroxidase enzyme responsible for thyroid hormone production.

By blocking this enzyme, CARBIZOLE 10:

• Reduces T3 (triiodothyronine) and T4 (thyroxine) production
• Prevents excessive iodine uptake by the thyroid gland
• Helps in achieving euthyroid state (normal thyroid function)

The reduction in thyroid hormones leads to an improvement in symptoms such as weight loss, rapid heartbeat, excessive sweating, and nervousness in hyperthyroid patients.

Dosage and Administration

The dosage of Carbimazole 10mg varies depending on the severity of hyperthyroidism, patient response, and doctor's recommendation.

General Dosage Guidelines

1. Mild Hyperthyroidism – 10-15 mg per day
2. Moderate Hyperthyroidism – 20-30 mg per day
3. Severe Hyperthyroidism – 40-60 mg per day

The total daily dose is usually divided into 2-3 doses throughout the day. Once the thyroid function stabilizes, the doctor may gradually reduce the dosage to a maintenance dose of 5-15 mg per day.

How to Take CARBIZOLE 10

• Take the tablet with or without food
• Swallow with water; do not chew or crush
• Take at the same time each day to maintain steady blood levels
• Follow the doctor's prescribed course duration without stopping early

Side Effects of CARBIZOLE 10

While CARBIZOLE 10 is generally well-tolerated, some patients may experience side effects. Most side effects are mild and temporary, but severe reactions require immediate medical attention.

Common Side Effects

• Nausea and vomiting
• Skin rash and itching
• Headache and dizziness
• Joint pain and muscle aches
• Mild gastrointestinal upset

Serious Side Effects (Seek Medical Help Immediately)

• Agranulocytosis (low white blood cell count) – Symptoms include fever, sore throat, infections
• Liver problems – Symptoms include yellowing of skin (jaundice), dark urine, severe fatigue
• Severe allergic reactions – Swelling of the face, breathing difficulty, and chest tightness
• Bone marrow suppression – Can lead to low red blood cells, white blood cells, and platelets

If you experience any severe symptoms, contact your doctor immediately.

Precautions and Warnings

1. Pregnancy and Breastfeeding

• CARBIZOLE 10 is not recommended in pregnancy, especially during the first trimester, due to the risk of fetal abnormalities.
• Breastfeeding mothers should consult a doctor before using this medication, as Carbimazole can pass into breast milk.

2. Liver and Kidney Disease

• Patients with liver dysfunction should use this medication with caution as it can affect liver function.
• Those with kidney disease should consult a doctor for proper dosage adjustments.

3. Blood Disorders

• CARBIZOLE 10 can cause agranulocytosis, a rare but serious condition that lowers white blood cell count.
• Patients should have regular blood tests to monitor for early signs of this condition.

4. Drug Interactions

CARBIZOLE 10 may interact with the following medications:

• Warfarin and anticoagulants – Increased risk of bleeding
• Beta-blockers – May enhance the effects of anti-thyroid drugs
• Digoxin – Thyroid function changes may affect drug levels
• Theophylline – Carbimazole can alter the metabolism of this drug

Always inform your doctor about any medications you are currently taking.

Lifestyle and Dietary Recommendations for Hyperthyroidism

To enhance the effectiveness of CARBIZOLE 10, patients should adopt a healthy lifestyle and diet:

• Avoid excessive iodine intake (seaweed, fish, iodized salt)
• Eat a balanced diet rich in vegetables, lean proteins, and whole grains
• Limit caffeine and stimulants that can increase heart rate
• Stay hydrated and maintain a healthy weight
• Manage stress through yoga, meditation, and relaxation techniques

Price of CARBIZOLE 10 in India

The Carbimazole 10mg price may vary depending on the brand, manufacturer, and pharmacy location. Generally, a strip of 10 tablets costs around ₹50-₹150 in India. Prices can differ based on availability and pharmacy discounts.

Conclusion

CARBIZOLE 10 (Carbimazole 10mg) is an effective antithyroid medication used to manage hyperthyroidism, Graves' disease, and pre-surgical thyroid treatment. By reducing excessive thyroid hormone production, it helps restore hormonal balance and prevents complications associated with an overactive thyroid.

While the medication is generally safe and effective, it is essential to follow the prescribed dosage, monitor for side effects, and undergo regular blood tests to ensure optimal results. Patients should also adopt a healthy lifestyle and dietary changes to support thyroid health.

If you are experiencing symptoms of hyperthyroidism, consult your doctor or endocrinologist for the best treatment plan, including whether CARBIZOLE 10 is suitable for you.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

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