Carbimazole 10mg

Oct 29, 2022

Introduction

CARBIZOLE 10 is a prescription medication containing Carbimazole 10 mg, used primarily in the treatment of hyperthyroidism, also known as an overactive thyroid. Carbimazole works by inhibiting the production of thyroid hormones, helping normalize metabolism and reduce symptoms caused by excessive thyroid activity.This antithyroid drug is widely prescribed as a first-line treatment before radioactive iodine therapy or thyroid surgery, and is also used for long-term thyroid hormone control.

Composition Details

Carbimazole 10 mg

  • Class: Antithyroid drug (Thioamide)

  • Mechanism of Action: Carbimazole is converted into methimazole in the body, which blocks thyroid peroxidase, an enzyme crucial for thyroid hormone synthesis (T3 and T4).

Carbimazole Uses (CARBIZOLE 10)

Tab Carbimazole 10 mg uses include:

  • Management of hyperthyroidism (overactive thyroid gland)

  • Pre-treatment before thyroidectomy or radioactive iodine therapy

  • Treatment of Graves’ disease

  • Used in toxic multinodular goitre

  • Helps control thyrotoxicosis symptoms like weight loss, palpitations, anxiety, and heat intolerance

How Does CARBIZOLE 10 Work?

CARBIZOLE 10 contains Carbimazole, which gets converted into methimazole in the body. Methimazole inhibits the enzyme thyroid peroxidase, which is essential for the production of thyroxine (T4) and triiodothyronine (T3).

By reducing the synthesis of these hormones, Carbimazole normalizes thyroid hormone levels, alleviates symptoms of hyperthyroidism, and stabilizes the patient’s metabolic rate.

Dosage and Administration

  • Starting Dose: Usually 10–30 mg/day, depending on the severity of hyperthyroidism.

  • Maintenance Dose: Once thyroid levels normalize, dose is reduced to 5–15 mg/day.

  • Route: Oral

  • Frequency: Once or twice daily after meals or as prescribed

  • Duration: Treatment may continue for 6–18 months or longer depending on clinical response.

Important: Dose must be tailored based on regular TSH, T3, and T4 levels. Do not alter or discontinue without physician approval.

Side Effects of Carbimazole 10 mg

Common side effects:

  • Nausea, vomiting

  • Skin rash or itching

  • Headache

  • Mild stomach discomfort

Less common but serious:

  • Agranulocytosis (dangerously low white blood cell count)

  • Sore throat, fever (report immediately)

  • Liver enzyme abnormalities or hepatitis

  • Joint pain (arthralgia)

Note: Patients must undergo regular blood tests to monitor blood cell counts and liver function during therapy.

Precautions and Warnings

  • Pregnancy: Use with caution. Carbimazole crosses the placenta; dose must be adjusted.

  • Breastfeeding: Small amounts pass into breast milk—consult a doctor.

  • Liver Impairment: Requires careful monitoring.

  • Agranulocytosis Warning: Patients must report fever, sore throat, or mouth ulcers immediately.

  • Do not stop abruptly without medical supervision.

Drug Interactions

  • Anticoagulants (e.g., warfarin): May increase bleeding risk

  • Beta-blockers: Enhanced effect as thyroid function normalizes

  • Theophylline, Digoxin: Dose adjustments may be necessary

  • Avoid combining with radioiodine therapy without physician guidance

Advantages of CARBIZOLE 10

  • Highly effective in controlling thyroid hormone levels

  • Helps manage Graves’ disease non-surgically

  • Offers symptom relief including weight loss, palpitations, and anxiety

  • Trusted formulation by Steris Healthcare with consistent quality

  • Ideal for preoperative thyroid preparation

Frequently Asked Questions (FAQs)

Q1. What is Carbimazole used for?

Carbimazole is used to treat hyperthyroidism, where the thyroid gland produces excessive thyroid hormones.

Q2. How does Carbimazole 10 mg tablet work?

It inhibits the enzyme responsible for thyroid hormone production, helping normalize T3 and T4 levels.

Q3. Can Carbimazole be taken during pregnancy?

Yes, but under strict medical supervision. Dose adjustments are necessary to prevent fetal hypothyroidism.

Q4. What are the side effects of Carbimazole?

Common side effects include nausea, rash, and headache. Serious side effect includes agranulocytosis, which requires immediate medical attention.

Q5. How long should I take CARBIZOLE 10?

Typically for 6–18 months or longer, depending on thyroid function and clinical symptoms.

Conclusion

CARBIZOLE 10, containing Carbimazole 10 mg, is an essential antithyroid medication for effectively managing hyperthyroidism and associated conditions. By reducing excess thyroid hormone production, it helps restore hormonal balance and prevent long-term complications. Backed by Steris Healthcare’s commitment to quality, CARBIZOLE 10 is a reliable choice for physicians and patients seeking effective thyroid management.

About The Company

Steris Healthcare Pvt Ltd, widely recognized as Sterispharma, was established in February 2018 by a team of seasoned experts from the pharmaceutical sector. Based in Navi Mumbai, the company is proudly certified by WHO, GMP, and ISO, underscoring its unwavering commitment to quality and patient safety. Sterispharma is driven by a mission to make affordable, premium-quality medicines accessible throughout India, adhering strictly to WHO-recommended standards. Through its user-friendly online pharmacy platforms, customers can effortlessly order medications with home delivery services.

Sterispharma boasts an extensive portfolio of healthcare solutions, ranging from treatments for rare diseases to essential everyday healthcare needs. Their comprehensive product lineup addresses multiple therapeutic areas including Cardiology, Asthma, Respiratory Disorders, Nasal Care, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infective/Antibiotic Therapy, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology. Medications are easily available for online purchase through their official websites — Sterisonline, Sterisindia, and Sterispharma — offering a seamless and reliable healthcare experience.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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