BUDEPRESS PLUS: Budesonide, Glycopyrronium & Formoterol for Respiratory Health

Chronic respiratory diseases such as Chronic Obstructive Pulmonary Disease (COPD) and severe asthma are major health concerns in India. Rising air pollution, smoking, occupational dust exposure, and biomass fuel smoke have significantly increased the burden of long-term breathing disorders. Symptoms like persistent breathlessness, wheezing, chest tightness, and chronic cough can seriously affect daily life if not managed properly.

BUDEPRESS PLUS is an advanced triple-combination inhalation therapy designed to provide comprehensive and long-lasting control of obstructive airway diseases. It contains Budesonide IP (400 mcg), Glycopyrronium (25 mcg), and Formoterol Fumarate (12 mcg)—three clinically proven medicines that work together to improve lung function, reduce inflammation, and keep airways open for extended periods.

BUDEPRESS PLUS is commonly prescribed for patients who require stronger and more effective respiratory support, especially those with moderate to severe COPD or poorly controlled asthma.

Composition of BUDEPRESS PLUS

Each dose of BUDEPRESS PLUS Inhaler contains:

• Budesonide IP – 400 mcg

• Glycopyrronium – 25 mcg

• Formoterol Fumarate – 12 mcg

This triple therapy approach is recommended by global and Indian respiratory guidelines for better symptom control and reduced exacerbations.

Understanding the Active Ingredients

Budesonide IP (400 mcg)

Budesonide is an inhaled corticosteroid (ICS) that reduces inflammation inside the airways. Inflammatory swelling and excess mucus are key causes of airflow limitation in asthma and COPD. Budesonide helps:

• Reduce airway swelling

• Control mucus production

• Prevent frequent flare-ups

• Improve long-term lung health

Because it is inhaled, budesonide acts directly in the lungs with minimal systemic side effects when used correctly.

Glycopyrronium (25 mcg)

Glycopyrronium is a long-acting muscarinic antagonist (LAMA). It works by blocking acetylcholine receptors in the airways, preventing muscle tightening and narrowing of bronchial tubes.

Key benefits include:

• Sustained airway relaxation

• Reduced breathlessness

• Improved airflow

• Better symptom control throughout the day

Glycopyrronium plays a crucial role in COPD management, especially in patients with persistent symptoms.

Formoterol Fumarate (12 mcg)

Formoterol is a long-acting beta-2 agonist (LABA) that relaxes airway muscles and keeps them open for up to 12 hours. It has a rapid onset of action compared to other LABAs.

Formoterol helps:

• Relieve wheezing

• Reduce chest tightness

• Improve exercise tolerance

• Enhance breathing comfort

How BUDEPRESS PLUS Works

BUDEPRESS PLUS offers triple-action respiratory support:

1. Budesonide reduces inflammation and prevents airway swelling

2. Formoterol relaxes airway muscles quickly and for a long duration

3. Glycopyrronium prevents airway tightening and maintains open airways

Together, they:

• Improve lung function

• Reduce frequency of exacerbations

• Control day and night symptoms

• Enhance quality of life

This makes BUDEPRESS PLUS an effective maintenance inhaler for long-term respiratory disease control.

Uses of BUDEPRESS PLUS

1. Chronic Obstructive Pulmonary Disease (COPD)

BUDEPRESS PLUS is widely used in:

• Moderate to severe COPD

• Patients with frequent exacerbations

• Individuals with persistent breathlessness despite dual therapy

It helps reduce hospital visits, improve lung capacity, and provide sustained symptom relief.

2. Severe or Uncontrolled Asthma

For patients whose asthma is not adequately controlled with standard inhalers, BUDEPRESS PLUS may be prescribed to:

• Reduce asthma attacks

• Improve airflow

• Control chronic inflammation

3. Long-Term Maintenance Therapy

BUDEPRESS PLUS is not meant for sudden breathing attacks. It is used daily as a preventive and maintenance treatment to keep symptoms under control.

Benefits of BUDEPRESS PLUS

• Triple therapy in a single inhaler

• Long-lasting bronchodilation

• Strong anti-inflammatory action

• Reduces frequency of flare-ups

• Improves lung function and oxygen flow

• Controls both daytime and night-time symptoms

• Convenient and patient-friendly

Dosage and Administration

Recommended Dosage

• Dosage is decided by the physician based on disease severity

• Commonly 1 inhalation once or twice daily

Always follow your doctor’s instructions.

How to Use BUDEPRESS PLUS Inhaler Correctly

Proper inhaler technique is essential for maximum benefit.

1. Shake the inhaler well

2. Breathe out completely

3. Place the mouthpiece between lips

4. Inhale deeply while pressing the inhaler

5. Hold breath for about 10 seconds

6. Breathe out slowly

7. Rinse mouth with water after use

Rinsing helps prevent throat irritation and fungal infections.

Missed Dose and Overdose

Missed Dose

• Take the missed dose as soon as remembered

• Skip if close to the next dose

• Do not double the dose

Overdose

Excess use may cause:

• Tremors

• Palpitations

• Headache

• Dry mouth

Seek medical advice immediately if overdose is suspected.

Side Effects of BUDEPRESS PLUS

Most patients tolerate BUDEPRESS PLUS well.

Common Side Effects

• Throat irritation

• Hoarseness

• Dry mouth

• Headache

Less Common Side Effects

• Oral fungal infection

• Mild tremors

• Increased heart rate

Rare Side Effects

• Allergic reactions

• Worsening breathing difficulty

Using correct inhaler technique significantly reduces side effects.

Precautions and Warnings

Before using BUDEPRESS PLUS, inform your doctor if you have:

• Heart disease

• High blood pressure

• Diabetes

• Glaucoma or prostate problems

• Active lung infections or tuberculosis

Pregnancy and Breastfeeding

Use only if clearly advised by a healthcare professional.

Elderly Patients

Close monitoring may be required due to coexisting medical conditions.

Drug Interactions

Inform your doctor if you are taking:

• Other bronchodilators

• Beta-blockers

• Antifungal medicines

• Steroid medications

Who Should Avoid BUDEPRESS PLUS?

• Patients allergic to any ingredient

• Individuals needing immediate relief for acute attacks

• Patients not advised by a physician

Importance of BUDEPRESS PLUS in Indian Healthcare

In India, COPD and asthma are often underdiagnosed and undertreated. Environmental pollution, smoking, and indoor air exposure worsen symptoms. BUDEPRESS PLUS offers a modern, evidence-based solution that simplifies treatment and improves patient adherence by combining three essential medicines in one inhaler.

Storage Instructions

• Store below 25°C

• Protect from heat and direct sunlight

• Do not puncture the inhaler

• Keep out of reach of children

Why Choose BUDEPRESS PLUS?

• Advanced triple-combination therapy

• Clinically proven ingredients

• Effective for severe respiratory conditions

• Reduces hospitalizations and flare-ups

• Improves breathing comfort and daily activity

Conclusion

BUDEPRESS PLUS, containing Budesonide IP 400 mcg, Glycopyrronium 25 mcg, and Formoterol Fumarate 12 mcg, is a powerful and effective inhalation therapy for managing moderate to severe COPD and uncontrolled asthma. Its triple-action formula addresses inflammation, bronchoconstriction, and airway tightening—offering comprehensive respiratory control.

Frequently Asked Questions 

Is BUDEPRESS PLUS a steroid inhaler?

Yes, it contains budesonide, an inhaled corticosteroid.

Is BUDEPRESS PLUS used for sudden asthma attacks?

No, it is a maintenance inhaler. A rescue inhaler should be used for sudden symptoms.

Can BUDEPRESS PLUS be used daily?

Yes, it is designed for regular daily use under medical supervision.

How long does it take to show improvement?

Symptom improvement may start within a few days, with full benefit seen after consistent use.

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