Benefits and Uses of Alpha Ketoanalogue (KETONALOG ALFA DS)

Jul 31, 2024

alpha ketoanalogue

Alpha ketoanalogue tablet is a specialized nutritional supplement used primarily in patients with chronic kidney disease (CKD) to delay the progression of kidney failure. It provides essential amino acids in their keto or hydroxy form, reducing the nitrogen load on kidneys and supporting better metabolic balance.KETONALOG ALFA DS is a clinically approved formulation from Steris Healthcare, containing high-quality Alpha Ketoanalogues that support kidney function while reducing uremic symptoms. It is typically prescribed alongside a low-protein diet to preserve kidney health and reduce the need for early dialysis.

What is an Alpha Ketoanalogue Tablet?

An alpha ketoanalogue tablet is a blend of essential amino acid analogues — specifically the keto forms — which, when ingested, convert into amino acids without releasing harmful nitrogenous waste. This makes them ideal for patients with compromised kidney function who need protein nutrition but cannot tolerate the metabolic waste burden from normal protein intake.

Composition of KETONALOG ALFA DS

Each tablet contains a mixture of essential Alpha Ketoanalogues and Hydroxyanalogues of amino acids, such as:

  • L-Leucine

  • L-Isoleucine

  • L-Valine

  • L-Phenylalanine

  • L-Methionine

  • L-Threonine

  • L-Tryptophan

  • Calcium and other essential nutrients

These analogues bypass nitrogen metabolism and support protein synthesis without burdening the kidneys.

Alpha Ketoanalogue Tablet Uses

KETONALOG ALFA DS is indicated in:

  • Chronic Kidney Disease (CKD) – stage 3 to stage 5 (non-dialysis)

  • Delayed progression of renal failure

  • Protein-energy malnutrition in renal patients

  • Patients on restricted-protein diets

Benefits of Alpha Ketoanalogue Tablets:

  • Reduce urea and nitrogen waste production

  • Improve nutritional status in kidney patients

  • Delay the need for dialysis

  • Support muscle mass and protein balance

  • Reduce symptoms of uremia (fatigue, nausea, confusion)

Alpha Ketoanalogue Tablet Uses in Hindi (अल्फा कीटोएनालॉग टैबलेट के उपयोग)

अल्फा कीटोएनालॉग टैबलेट का उपयोग क्रोनिक किडनी डिज़ीज (CKD) के रोगियों में किया जाता है ताकि किडनी की कार्यक्षमता को बनाए रखा जा सके और डायलिसिस की आवश्यकता को टाला जा सके।

मुख्य उपयोग हिंदी में:

  • पुरानी गुर्दे की बीमारी (क्रॉनिक किडनी डिज़ीज)

  • शरीर में नाइट्रोजन अपशिष्ट कम करना

  • कम प्रोटीन डाइट के साथ पोषण बनाए रखना

  • मांसपेशियों की कमजोरी और कुपोषण से बचाव

  • डायलिसिस में देरी करना

Mechanism of Action

Alpha ketoanalogues act as precursors to amino acids but do not contain nitrogen. When consumed:

  • They convert to essential amino acids in the body

  • Support protein synthesis in muscle and tissues

  • Help reduce production of nitrogenous waste like urea, thereby reducing the burden on failing kidneys

  • Support overall nutritional balance in CKD patients

Dosage and Administration

  • Usual Dose: 1 tablet per 5 kg body weight per day
    (e.g., 6 tablets daily for a 60 kg patient)

  • Administration: To be taken with meals

  • Recommended Diet: Low-protein diet (under medical supervision)

Do not self-prescribe. Always use under the guidance of a nephrologist or healthcare provider.

Side Effects of Alpha Ketoanalogue Tablets

Generally well-tolerated, but possible side effects include:

  • Hypercalcemia (high calcium levels)

  • Upset stomach or indigestion

  • Nausea (rare)

  • Electrolyte imbalance (if not monitored properly)

Monitoring Tip: Regular kidney function and calcium levels should be checked during therapy.

Precautions

  • Not intended for dialysis-dependent patients

  • Should not replace complete protein needs — used alongside a protein-restricted diet

  • Monitor serum calcium, creatinine, and BUN levels

  • Pregnant and breastfeeding women should only take under strict medical guidance

Why Choose KETONALOG ALFA DS by Steris Healthcare?

  • Scientifically balanced amino acid analogues

  • High bioavailability with minimal side effects

  • WHO-GMP certified manufacturing standards

  • Designed for long-term renal support

  • Trusted by nephrologists and dietitians across India

Frequently Asked Questions (FAQs)

1. What is the use of alpha ketoanalogue tablet in kidney disease?

Alpha ketoanalogue tablets** help patients with chronic kidney disease by providing protein nutrition without increasing the nitrogenous waste burden on the kidneys. They slow disease progression and help maintain health.

2. Can alpha ketoanalogue tablets delay dialysis?

Yes, when used early in CKD with a low-protein diet, they can help delay the need for dialysis.

3. How long can I take KETONALOG ALFA DS?

As long as prescribed by your doctor. It’s often used for long-term nutritional management in CKD.

4. Do alpha ketoanalogue tablets have any side effects?

Side effects are rare but may include high calcium levels or mild digestive issues.

5. Should alpha ketoanalogue tablets be taken with food?

Yes, always take them with meals for maximum absorption and conversion into amino acids.

6. Are alpha ketoanalogues suitable for dialysis patients?

Generally, they are recommended before dialysis stage. For dialysis patients, protein needs are different and should be addressed separately.

Conclusion

KETONALOG ALFA DS is a clinically proven alpha ketoanalogue tablet formulation that helps manage chronic kidney disease and delays the progression to dialysis. By supplying essential amino acid analogues without adding nitrogen load, it supports nutritional balance in patients on low-protein diets. If you or your loved one has early-stage kidney disease, ask your nephrologist about KETONALOG ALFA DS — a trusted support for kidney health by Steris Healthcare.

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