Apixaban (2.5mg) & APIXAZEN 2.5 Mg : upto 30% discount by Sterispharma

Introduction

APIXAZEN 2.5 contains Apixaban 2.5 mg, a novel oral anticoagulant (NOAC) that selectively inhibits Factor Xa, reducing the risk of blood clot formation. It is used in patients at risk of thromboembolic events, including after major orthopedic surgery and in conditions like non-valvular atrial fibrillation.

Manufactured under WHO-GMP standards, APIXAZEN 2.5 offers:

• Predictable anticoagulation

• No need for INR monitoring

• Minimal food and drug interactions

Composition

• Active Ingredient: Apixaban 2.5 mg

• Dosage Form: Film-coated oral tablet

• Route of Administration: Oral

Indications & Uses

APIXAZEN 2.5 is indicated for:

• VTE prevention after hip/knee replacement surgery

• Extended DVT/PE prophylaxis after initial treatment

• Stroke prevention in non-valvular atrial fibrillation (special populations)

• Secondary prevention of thromboembolic events

Note: Often used in elderly patients, those with renal impairment, or low body weight.

Mechanism of Action

Apixaban selectively and reversibly inhibits Factor Xa, preventing the conversion of prothrombin to thrombin, and thus blocking clot formation.
It works independently of antithrombin III and provides a stable pharmacokinetic profile, enabling fixed-dose therapy without regular coagulation monitoring.

Dosage & Administration

Standard Dose: 2.5 mg twice daily

Surgical Prophylaxis:

• Knee replacement: 10–14 days

• Hip replacement: 28–35 days

Contraindications

• Active bleeding

• Severe hepatic impairment

• Hypersensitivity to Apixaban

• Concurrent use with strong CYP3A4 & P-gp inhibitors

Warnings & Precautions

• Pre-surgical use: Discontinue temporarily

• Renal impairment: Monitor function regularly

• Bleeding risks: Caution in GI ulcers, recent surgery

• Liver function: Not advised in severe hepatic disease

Possible Side Effects

Common:

• Bruising, nosebleeds, bleeding gums

• Nausea, anemia, indigestion

Serious (Rare):

• Gastrointestinal or intracranial bleeding

• Rash, hypersensitivity reactions

• Elevated liver enzymes

Drug Interactions

Avoid with:

• Strong CYP3A4 & P-gp inhibitors (e.g., ketoconazole, ritonavir)

• Strong inducers (e.g., rifampicin, phenytoin)

Use cautiously with:

• NSAIDs

• Antiplatelet drugs (aspirin, clopidogrel)

• SSRIs/SNRIs

Packaging

• Strength: Apixaban 2.5 mg

• Tablet: Round, biconvex, film-coated

Storage Instructions

• Store below 25°C

• Protect from moisture & sunlight

• Keep out of reach of children

Frequently Asked Questions (FAQs)

Q. Can APIXAZEN 2.5 be taken with food?
Yes, it can be taken with or without food.

Q. Is blood monitoring required like with warfarin?
No. Apixaban does not require INR or routine coagulation monitoring.

Q. Can patients with kidney problems use APIXAZEN?
Yes, with caution. Dose adjustments may be required in moderate renal impairment.

Q. Can I stop taking it suddenly?
No. Sudden discontinuation may increase the risk of clot formation. Always consult your doctor.

Conclusion

APIXAZEN 2.5 (Apixaban 2.5 mg) offers an advanced, convenient, and clinically proven solution for thromboprophylaxis. Its predictable action, lower bleeding risk, and fixed-dose regimen make it a valuable choice in long-term anticoagulation therapy—especially for patients where safety and ease of use are paramount.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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