Amiodarone (200mg) & AMIDRONE 200 Mg : Essential Medications for Heart Health
Jun 17, 2024
Introduction
AMIDRONE 200 is a widely prescribed medication belonging to the antiarrhythmic class, known for its effectiveness in managing various cardiac rhythm disorders. Its active ingredient, Amiodarone Hydrochloride, plays a crucial role in restoring and maintaining a normal heartbeat. The medication is especially beneficial for patients suffering from ventricular and supraventricular arrhythmias, conditions that can severely disrupt the heart's electrical activity.
This article provides a detailed overview of the amiodarone 200 mg tablet, marketed under the brand name AMIDRONE 200, including its medical uses, recommended dosage, mechanism of action, potential side effects, and commonly asked questions. Whether you are a patient prescribed this medication or someone researching its benefits and risks, this guide will help you understand everything you need to know about amiodarone tablet uses and precautions.
About This Medication
AMIDRONE 200 contains amiodarone 200 mg tablet as its active component. It is categorized under Class III antiarrhythmic agents and works by affecting the electrical impulses that control heart rhythm. This slows down nerve activity in the heart and stabilizes irregular heartbeats.
Key Highlights:
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Generic Name: Amiodarone Hydrochloride tablet
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Brand Name: AMIDRONE 200
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Strength: 200 mg
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Form: Oral tablet
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Therapeutic Use: Antiarrhythmic
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Prescription Status: Prescription-only medication
TABLET USES
The amiodarone 200 mg tablet has several essential uses in cardiology, especially in the treatment of chronic and life-threatening arrhythmias.
Primary Uses of AMIDRONE 200:
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Ventricular Tachycardia: A fast heart rate that originates from the lower chambers (ventricles).
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Ventricular Fibrillation: Chaotic heart rhythms leading to ineffective blood pumping and possibly cardiac arrest.
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Supraventricular Tachycardia (SVT): Includes atrial fibrillation and atrial flutter, which affect the heart's upper chambers.
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Prevention of Recurrence: After cardioversion in patients with atrial fibrillation, amiodarone tablet uses also include preventing recurrence.
These amiodarone uses make AMIDRONE 200 a life-saving medication for people dealing with potentially dangerous heart rhythm disturbances.
DOSAGE
Recommended Dose for Adults:
The dosage of amiodarone 200 mg tablet depends on the severity of the condition and the patient's response to the drug.
Initial Loading Dose:
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Usually, 800 mg to 1600 mg per day, divided into multiple doses.
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This phase typically lasts 1-3 weeks to saturate the body with enough medication to control the rhythm.
Maintenance Dose:
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Typically amiodarone 200 mg tablet once or twice daily, depending on the therapeutic response.
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In some cases, doses may be reduced to 100 mg per day after adequate control of arrhythmia.
Route of Administration:
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Oral, preferably with food to reduce gastrointestinal discomfort.
How AMIDRONE 200 Works
AMIDRONE 200 alters the potassium channels in cardiac muscle cells, prolonging the repolarization phase of the action potential. This means it increases the time it takes for the heart muscle to electrically recharge, which helps correct abnormal rhythms and prevents further episodes.
Additional Benefits:
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Decreases abnormal automaticity of the heart.
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Slows conduction of electrical signals.
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Mildly inhibits beta-adrenergic receptors.
Because of this multi-action profile, amiodarone 200 mg tablet is considered highly effective in managing complex arrhythmias.
What Are the Possible Side Effects of This Medicine?
Although AMIDRONE 200 is effective, it is associated with a broad range of side effects due to its action on multiple organ systems. Monitoring and regular follow-ups are essential while taking amiodarone 200 mg tablet.
Common Side Effects:
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Nausea
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Vomiting
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Loss of appetite
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Constipation
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Bitter or metallic taste
Serious Side Effects:
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Pulmonary toxicity – shortness of breath, dry cough (can be fatal in rare cases)
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Liver toxicity – elevated liver enzymes, jaundice
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Thyroid dysfunction – both hypo- and hyperthyroidism
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Skin discoloration – bluish-gray pigment on face and exposed areas
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Vision problems – halos, optic neuropathy
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Bradycardia – slow heart rate
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Peripheral neuropathy
Long-Term Use Risks:
Due to its long half-life, amiodarone 200 mg tablet remains in the body for weeks even after discontinuation. Therefore, long-term use requires regular liver, lung, thyroid, and eye checkups.
Precautions and Warnings
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Pregnancy and Breastfeeding: Not recommended unless the benefits outweigh the risks. It can harm the fetus or nursing infant.
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Drug Interactions: Can interact with digoxin, warfarin, statins, beta-blockers, and other antiarrhythmics.
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Grapefruit Juice: Avoid consuming as it increases the levels of amiodarone in the blood.
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Surgery or Anesthesia: Inform the anesthetist if you are on AMIDRONE 200.
Storage Instructions
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Store in a cool, dry place below 30°C.
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Keep away from moisture and direct sunlight.
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Keep out of reach of children.
Frequently Asked Questions (FAQs)
What is the lowest dose of amiodarone?
The lowest maintenance dose is typically 100 mg per day, but this must be prescribed and monitored by a healthcare provider.
Can I take AMIDRONE 200 long-term?
Yes, but it should be under strict medical supervision with regular tests for lungs, thyroid, liver, and eyes.
Is AMIDRONE 200 safe for elderly patients?
Caution is advised in elderly individuals due to the higher risk of side effects. Dose adjustment may be necessary.
Does AMIDRONE 200 cause weight gain?
Weight changes are not common, but thyroid-related side effects could lead to weight gain or loss.
Can I drink alcohol while taking amiodarone?
It is best to limit or avoid alcohol, as it can exacerbate side effects such as liver damage and dizziness.
How soon will AMIDRONE 200 start working?
Some effects may be seen within days, but full therapeutic effects may take 1-3 weeks, especially with a loading dose.
Is AMIDRONE 200 addictive or habit-forming?
No, it is not addictive. However, do not stop taking it abruptly.
Can AMIDRONE 200 be crushed or split?
Only if your doctor advises, as splitting the tablet may alter its effectiveness.
What happens if I miss a dose?
Take it as soon as you remember. If it's close to your next dose, skip the missed one. Do not double the dose.
What should I do in case of an overdose?
Seek emergency medical help. Overdose can lead to serious cardiac complications like bradycardia and hypotension.
Final Thoughts
AMIDRONE 200, containing amiodarone 200 mg tablet, is a powerful medication used to control complex cardiac rhythm disorders. Its effectiveness in treating ventricular and supraventricular arrhythmias makes it a cornerstone in antiarrhythmic therapy. However, it is equally important to be aware of its side effects and the necessity of regular medical monitoring.
From managing critical heart conditions to preventing life-threatening rhythm disturbances, the amiodarone tablet uses of AMIDRONE 200 highlight its significant role in cardiac care. But its administration should always be under the strict guidance of a healthcare provider due to potential side effects, interactions, and organ-specific risks.
If you or a loved one is prescribed this medication, ensure to discuss all medical history and undergo the required routine tests for safe and effective therapy. With informed use, AMIDRONE 200 can be a life-changing medication for those battling arrhythmias.
About The Author
Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.
For further information
Email: info@sterispharma.com / contact@sterispharma.com
Call/WhatsApp: 8209542042 , 8824175417
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