Patients suffering from chronic kidney disease (CKD), acute kidney injury (AKI), or those on dialysis often struggle with severe nutritional deficiencies. Due to impaired renal function, the body’s ability to effectively absorb and utilize essential amino acids becomes compromised. This leads to muscle wasting, weakness, poor immunity, delayed healing, and reduced overall health outcomes.

STERIMIN NEPHRO 7%, a specialized Amino Acids Injection 7% formulation from Steris Healthcare Pvt. Ltd., is designed to bridge these nutritional gaps safely and efficiently. It provides a balanced, clinically optimized blend of essential and non-essential amino acids tailored specifically for patients with renal impairment who need strong, reliable parenteral nutrition.

This advanced formulation ensures that patients with compromised kidneys receive the right nutrients without burdening their renal system, promoting better recovery, improved protein utilization, and enhanced metabolic balance.

What is STERIMIN NEPHRO 7%?

STERIMIN NEPHRO 7% is a sterile, balanced 7% amino acids injection intended for intravenous administration. It delivers essential amino acids required for protein synthesis, tissue repair, metabolic functioning, and overall nutritional support in patients who cannot meet their protein requirements orally.

This formulation is particularly valuable for:

• CKD patients

• Dialysis (hemodialysis/peritoneal dialysis) patients

• Critically ill patients with renal dysfunction

• AKI patients requiring parenteral nutrition

• Post-surgical patients with renal compromise

• Severely malnourished renal patients

It provides safe, efficient, and clinically validated amino acid support without overloading the kidneys.

Composition of STERIMIN NEPHRO 7%

The solution contains a 7% w/v mixture of essential and non-essential amino acids, offering:

• Essential amino acids needed for tissue repair, muscle building, immunoprotection

• Non-essential amino acids for metabolic balance and protein synthesis

• High biological value protein source

• Optimal nitrogen content suitable for renal patients

• Formulation designed to improve protein utilisation without increasing nitrogen waste

Each amino acid in the formulation is included in a physiologically appropriate ratio to ensure maximum metabolic utilization.

Why Amino Acid Supplementation Is Essential in Renal Patients

Patients with impaired kidney function experience:

1. Protein-Energy Wasting (PEW)

A serious metabolic condition causing:

• Muscle wasting

• Low albumin levels

• Weakness

• Reduced immunity

2. Catabolic Stress

Due to inflammation, toxin accumulation, and dialysis-related muscle breakdown.

3. Reduced Appetite

Making oral nutrition insufficient.

4. Impaired Protein Metabolism

Kidneys fail to excrete metabolic waste efficiently, making targeted amino acid support essential.

5. Increased Amino Acid Loss

Dialysis removes not just toxins but also essential amino acids from blood.

STERIMIN NEPHRO 7% helps overcome these nutritional challenges by delivering precise nutrients intravenously.

How STERIMIN NEPHRO 7% Works (Mechanism of Action)

1. Supports Protein Synthesis

Provides essential building blocks for tissue growth and repair.

2. Replenishes Amino Acids Lost During Dialysis

Helps maintain metabolic balance.

3. Enhances Muscle Strength

Promotes muscle mass restoration and prevents wasting.

4. Improves Immunity

Amino acids strengthen immune responses and healing capacity.

5. Promotes Wound Healing

Ideal for post-surgical renal patients.

6. Maintains Nitrogen Balance

Balanced formulation prevents nitrogen overload.

Uses of STERIMIN NEPHRO 7%

STERIMIN NEPHRO 7% is indicated for:

1. Chronic Kidney Disease (CKD)

To manage nutritional deficiencies, prevent muscle loss, and maintain body protein stores.

2. Dialysis Patients

Helps replace amino acids lost during dialysis and improves overall nutritional status.

3. Acute Kidney Injury (AKI)

Supports critically ill patients who can’t consume adequate nutrition orally.

4. Post-Surgical Renal Patients

Promotes faster recovery, tissue repair, and wound healing.

5. Malnutrition Associated with Kidney Disease

Corrects severe protein-energy malnutrition.

6. Critical Care Nutrition

Provides vital amino acids during severe illness or trauma.

Benefits of STERIMIN NEPHRO 7%

1. Designed Specifically for Renal Patients

The formulation is optimized for renal metabolism.

2. Prevents Muscle Wasting

Helps maintain muscle mass and strength.

3. Enhances Recovery

Ideal for hospital, ICU, and surgical patients.

4. Improves Immunity

Strengthens the body’s natural defense.

5. Balanced Nitrogen Content

Ensures safe protein support even in compromised kidney function.

6. Easy to Administer

Sterile IV formulation ensures immediate availability and absorption.

7. Reduces Hospital Stay Duration

Improves nutritional status, leading to faster recovery.

8. Enhances Quality of Life

Better nutrition leads to better strength, mobility, and overall well-being.

Dosage & Administration

Route of Administration

• Intravenous infusion only

• To be administered under the supervision of qualified healthcare professionals.

Dosage

The dosage depends on:

• Patient’s nutritional status

• Renal function

• Degree of catabolic stress

• Dialysis schedule

• Age and body weight

Doctors typically determine the appropriate dose per day. Infusion rates must be controlled to avoid complications.

Duration

Used as part of parenteral nutrition until oral intake improves or as recommended.

Safety Profile of STERIMIN NEPHRO 7%

STERIMIN NEPHRO 7% is well tolerated when administered correctly. However, like all IV nutritional formulations, the following may occur:

Common Side Effects

• Mild nausea

• Local infusion site pain

• Slight discomfort

Less Common

• Electrolyte imbalance

• Metabolic acidosis if given too rapidly

• Allergic reactions (rare)

Serious but Rare

• Hyperammonemia in predisposed patients

• Circulatory overload if infused rapidly

All infusions must be monitored by medical professionals.

Precautions & Warnings

• To be used strictly under medical supervision.

• Not for oral use.

• Adjust dosage in hepatic impairment.

• Avoid rapid administration.

• Periodic monitoring of:

  • Electrolytes

  • Renal function

  • Liver function

  • Serum proteins

  • Nitrogen balance

Contraindications

• Hypersensitivity to amino acids

• Severe metabolic acidosis

• Inborn amino acid metabolism disorders

Why STERIMIN NEPHRO 7% is Superior to Competitors

1. Balanced Renal-Specific Formulation

Designed to reduce nitrogen load while maximizing protein utilization.

2. Enhanced Purity

Manufactured under strict quality standards ensuring safety and stability.

3. Superior Absorption

Formulated for optimal metabolism even in critically ill renal patients.

4. Backed by Steris Healthcare’s Expertise

Reliable pharmaceutical formulation trusted by clinicians across India.

5. Competitive Pricing

High-quality amino acid nutrition at an affordable cost.

6. Ideal Amino Acid Ratio

Ensures maximum metabolic utilization.

7. Excellent Tolerability

Low risk of infusion-related reactions.

Who Needs STERIMIN NEPHRO 7%?

1. Patients on Hemodialysis or Peritoneal Dialysis

To compensate for amino acid losses.

2. CKD Patients with Low Protein Intake

Due to appetite loss or dietary restrictions.

3. ICU Patients with Renal Dysfunction

Provides essential nutrition when oral intake is insufficient.

4. Elderly Renal Patients

Prevents frailty and muscular weakness.

5. Malnourished Patients

Restores nutritional balance.

6. Surgical & Post-Operative Patients

Promotes healing and tissue recovery.

Clinical Importance of Amino Acid Therapy in Renal Disease

1. Supports Protein Turnover

Renal patients experience rapid protein breakdown. Amino acids are essential for synthesis.

2. Maintains Albumin Levels

Low albumin increases hospital stay, infection risk, and mortality.

3. Improves Dialysis Outcomes

Enhances strength and overall health.

4. Prevents Sarcopenia

Muscle wasting weakens immunity and mobility.

5. Improves Metabolic Efficiency

A balanced amino acid profile helps maintain nitrogen balance.

Guidelines for Optimal Results

• Administer only via IV under supervision

• Monitor biochemical parameters regularly

• Ensure adequate caloric intake through carbohydrates and fats

• Combine with micronutrients for complete parenteral support

• Adjust dosage during dialysis days

Conclusion

STERIMIN NEPHRO 7% – Amino Acids Injection 7% is an essential part of nutritional therapy for patients affected by renal disorders. Its balanced amino acid formulation supports muscle strength, improves immunity, enhances healing, and prevents malnutrition-related complications. With its superior clinical profile, excellent tolerability, and the trust of Steris Healthcare, STERIMIN NEPHRO 7% stands as a powerful solution to improve health outcomes in renal patients.

Frequently Asked Questions 

1. Why do renal patients need amino acid injections?

To prevent muscle wasting, support healing, and improve overall nutrition when oral intake is inadequate.

2. Is STERIMIN NEPHRO 7% safe for dialysis patients?

Yes, it is formulated especially for dialysis-related amino acid losses.

3. Can it be used in AKI?

Yes, under strict medical supervision.

4. Can it be used long-term?

Yes, as part of a guided parenteral nutrition plan.

5. How soon can patients feel improvement?

Muscle strength and energy levels often improve within 1–2 weeks.

6. Is it safe for elderly patients?

Yes, especially beneficial for malnutrition-related weakness.