Pimavanserin 34 mg Tablet: PIMASERIN 34 Available in Steris.

PIMASERIN 34 is a prescription medication containing Pimavanserin 34mg, primarily used for the treatment of psychotic symptoms associated with Parkinson’s disease. It is designed to improve the quality of life for patients by targeting hallucinations and delusions without worsening motor symptoms commonly associated with Parkinson’s disease.

Pimavanserin is a selective serotonin inverse agonist that acts on 5-HT2A receptors in the brain. Unlike traditional antipsychotics, it does not block dopamine receptors, making it safer for Parkinson’s patients who are sensitive to dopamine antagonists.

Composition

• Active Ingredient: Pimavanserin 34mg

• Formulation: Tablet

• Brand Name: PIMASERIN 34

PIMASERIN 34 provides a precise dose of pimavanserin, ensuring consistent therapeutic effects with minimal side effects.

Uses of PIMASERIN 34

1. Parkinson’s Disease Psychosis (PDP):
   PIMASERIN 34 is primarily prescribed to manage hallucinations and delusions in patients with Parkinson’s disease. It helps reduce psychiatric symptoms while preserving motor function.

2. Other Off-Label Uses:
   In some cases, doctors may prescribe pimavanserin for other psychiatric conditions, including schizophrenia-related hallucinations or agitation in elderly patients, but always under strict medical supervision.

How PIMASERIN 34 Works

Pimavanserin, the active ingredient, functions as a selective serotonin 5-HT2A receptor inverse agonist:

• Targeting hallucinations and delusions: By modulating serotonin receptors, it reduces abnormal brain signaling that causes psychotic symptoms.

• Maintaining dopamine balance: Unlike other antipsychotics, it does not interfere with dopamine pathways, preserving motor function in Parkinson’s patients.

• Improving quality of life: By alleviating psychotic symptoms, patients experience better daily functioning and mental stability.

Dosage and Administration

Important: Dosage must follow the doctor’s prescription. Individual needs may vary based on age, condition severity, and medical history.

• Recommended Dose: 34mg once daily, preferably at the same time each day.

• Administration: Oral, with or without food. Swallow tablets whole.

• Pediatric Use: Safety and efficacy not established for patients under 18.

• Geriatric Use: Standard dosing is generally appropriate, but monitoring for side effects is recommended.

Tips for patients:

• Take at the same time every day for consistent therapeutic levels.

• Avoid sudden discontinuation, as it may worsen symptoms.

Before Using PIMASERIN 34

Allergies:

Do not take PIMASERIN 34 if allergic to pimavanserin or any tablet components.

Medical History:

Inform your doctor about any history of:

• Heart rhythm disorders (QT prolongation)

• Liver or kidney impairment

• Low blood pressure or cardiovascular issues

Pregnancy and Breastfeeding:

• Pregnancy: Safety is not well-established; use only if clearly indicated.

• Breastfeeding: Consult a doctor; minimal data available.

Pediatric and Geriatric Considerations:

• Children under 18: Not recommended

• Elderly patients: Regular monitoring is advised due to potential cardiovascular risks.

Drug Interactions

PIMASERIN 34 may interact with:

• CYP3A4 inhibitors: e.g., ketoconazole, clarithromycin – can increase pimavanserin levels

• Other antipsychotics or sedatives: May enhance side effects like dizziness or drowsiness

• QT-prolonging medications: Combining may increase risk of heart rhythm abnormalities

Always inform your doctor about all medications, including OTC drugs and supplements.

Other Interactions

• Alcohol: Can increase sedation and dizziness. Limit intake.

• Medical Conditions: Heart disease, liver disease, and kidney problems may require dose adjustments.

Proper Use

• Take exactly as prescribed.

• Do not alter the dose without medical guidance.

• Swallow tablets whole; do not crush, split, or chew.

• Keep regular follow-ups with your doctor for monitoring.

Missed Dose

• Take as soon as remembered.

• If close to the next dose, skip the missed dose.

• Never double up to compensate.

Storage

• Store at room temperature below 30°C.

• Keep away from moisture, heat, and direct sunlight.

• Store out of reach of children and pets.

Precautions

• Monitor for changes in heart rhythm (palpitations, irregular heartbeat).

• Avoid driving or operating machinery until you know how PIMASERIN 34 affects you.

• Inform your doctor immediately if you experience confusion, severe dizziness, or fainting.

• Regular liver and kidney function tests may be advised.

Side Effects

Common Side Effects:

• Nausea or vomiting

• Constipation or diarrhea

• Peripheral edema (swelling of hands/feet)

• Dizziness or drowsiness

Serious Side Effects (Seek Medical Help):

• Severe hallucinations or agitation

• Heart rhythm disturbances (QT prolongation)

• Allergic reactions: rash, itching, swelling

• Low blood pressure with fainting

Most side effects are mild and often subside as the body adjusts to treatment.

Benefits of PIMASERIN 34

1. Reduces hallucinations and delusions in Parkinson’s patients

2. Improves daily functioning and quality of life

3. Preserves motor function unlike traditional antipsychotics

4. Minimal risk of extrapyramidal side effects

5. Can be safely combined with other Parkinson’s therapies under medical supervision

Patient Tips for Optimal Results

• Take consistently at the same time daily.

• Avoid abrupt discontinuation.

• Stay hydrated and maintain a balanced diet.

• Report unusual symptoms promptly.

• Attend scheduled follow-ups and lab tests.

Conclusion

PIMASERIN 34 (Pimavanserin 34mg) is a breakthrough medication for managing psychosis in Parkinson’s disease. Its serotonin-selective action ensures effective treatment of hallucinations and delusions while preserving motor function. With proper use, precautions, and monitoring, PIMASERIN 34 significantly improves patient quality of life.

Patients should adhere strictly to prescribed doses, report side effects immediately, and maintain regular doctor consultations to achieve optimal outcomes.

FAQs (Frequently Asked Questions)

Q1: Can PIMASERIN 34 be used with other Parkinson’s medications?
A: Yes, but only under strict medical supervision to avoid interactions.

Q2: How quickly does PIMASERIN 34 work?
A: Some improvement in psychotic symptoms may be seen within a few weeks, but full benefits may take longer.

Q3: Is PIMASERIN 34 safe for elderly patients?
A: Yes, but careful monitoring is recommended due to potential cardiovascular risks.

Q4: Can PIMASERIN 34 cause sleepiness?
A: Drowsiness or dizziness may occur; avoid driving until you know its effects.

Q5: What should I do if I miss a dose?
A: Take it as soon as remembered unless it’s near the next scheduled dose. Do not double up.