Levosalbutamol and Ipratropium Bromide Respiratory Solution'''

Introduction

R.S. IPRATROP 1.25 is a combination bronchodilator respiratory solution containing Levosalbutamol and Ipratropium Bromide. This solution is used via nebulization for the treatment of bronchospasm in patients with chronic obstructive pulmonary disease (COPD), asthma, and other obstructive airway conditions. It offers dual-action relief by combining two different mechanisms of bronchodilation, resulting in improved airflow and respiratory function.

Composition

• Levosalbutamol (Levalbuterol) – 1.25 mg

• Ipratropium Bromide – 500 mcg

• Form: Respiratory solution for nebulization

• Brand: R.S. IPRATROP 1.25

What is Levosalbutamol & Ipratropium Bromide Respirator Solution Used For?

Primary Indications:

1. Chronic Obstructive Pulmonary Disease (COPD)

   • Emphysema

   • Chronic bronchitis

   • Mixed-type COPD

2. Bronchial Asthma

   • Acute exacerbations

   • Persistent or uncontrolled asthma despite monotherapy

3. Acute Bronchospasm

   • Sudden airway narrowing

   • Often used in emergency and ICU settings

4. Obstructive Airway Diseases

   • Post-viral wheezing

   • Allergic airway inflammation

Dual Bronchodilation Mechanism:

1. Levosalbutamol (1.25 mg):

• A short-acting beta-2 agonist (SABA).

• Relaxes bronchial smooth muscle by stimulating beta-2 receptors, promoting rapid bronchodilation.

• Provides quick relief from acute bronchospasm.

2. Ipratropium Bromide (500 mcg):

• A short-acting anticholinergic (SAMA).

• Blocks muscarinic receptors in the airways, reducing bronchial secretions and preventing bronchoconstriction.

• Works synergistically with Levosalbutamol for sustained respiratory relief.

Synergy: The combination is more effective than either drug alone, offering better symptom control and lung function improvement.

Dosage & Administration

How to Use:

• For use via nebulizer only.

• Contents of one unit-dose vial (usually 2.5 ml) should be nebulized over 10–15 minutes.

• Can be repeated 2–4 times daily or as prescribed.

Note:

• Shake well before use.

• Should not be injected or ingested.

• Use sterile nebulization technique.

Side Effects

Though generally well-tolerated, some patients may experience:

• Dry mouth or throat irritation

• Headache

• Palpitations or increased heart rate

• Muscle cramps

• Tremors or shakiness

• Cough or paradoxical bronchospasm (rare)

Seek immediate medical help in case of severe wheezing, chest pain, or allergic reactions.

Precautions & Warnings

• Use with caution in patients with heart disease, thyroid disorders, hypertension, or diabetes.

• Not recommended during pregnancy or breastfeeding unless prescribed.

• Avoid contact with eyes — may cause blurred vision or pupil dilation.

• Monitor blood potassium levels in chronic use cases (risk of hypokalemia).

Drug Interactions

• Avoid concurrent use with beta-blockers, MAO inhibitors, diuretics, or other bronchodilators without medical advice.

• Inform your doctor if you're on anticholinergic medications, corticosteroids, or cardiac drugs.

Storage Instructions

• Store at room temperature (below 25°C).

• Protect from direct sunlight and moisture.

• Discard unused solution after opening the vial.

FAQs About R.S. IPRATROP 1.25

Q1. What is R.S. IPRATROP 1.25 used for?

Ans: It is used for the treatment of bronchospasm in COPD, asthma, and other obstructive airway disorders via nebulization.

Q2. Can I use R.S. IPRATROP 1.25 during an asthma attack?

Ans: Yes, it provides fast and effective bronchodilation and is often used during acute asthma exacerbations under medical supervision.

Q3. How often can I use this solution?

Ans: Usually 2–4 times daily, depending on the severity of symptoms and physician recommendation.

Q4. Is this medication safe for children?

Ans: It may be used in pediatric cases if prescribed by a pediatrician, especially for acute wheezing or bronchiolitis.

Q5. Can I use this with other inhalers or nebulizer medicines?

Ans: Yes, but only after consulting your doctor. Some combinations may enhance side effects or interact.

Conclusion

R.S. IPRATROP 1.25 provides a potent combination of Levosalbutamol and Ipratropium Bromide in a nebulizer solution, delivering effective and fast-acting relief from bronchospasm and airflow obstruction. This dual therapy is widely used in the management of COPD, acute asthma, and chronic airway conditions, ensuring better lung function and improved breathing quality. As with all respiratory treatments, proper technique and medical guidance are essential for optimal results and safety.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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