Glimiteris Trio 0.5/0.2/500: A Comprehensive Solution for Type 2 Diabetes Management

Nov 30, 2024

Diabetes mellitus is one of the fastest-growing chronic lifestyle disorders in India, affecting millions of adults due to sedentary lifestyles, high-carbohydrate diets, obesity, and genetic factors. Type 2 Diabetes Mellitus (T2DM) is the most common form and requires careful management to prevent long-term complications such as heart disease, kidney damage, neuropathy, and vision problems.

GLIMITERIS TRIO 0.5/0.2/500 is a triple-action antidiabetic tablet that combines Glimepiride 0.5 mg, Voglibose 0.2 mg, and Metformin Hydrochloride (SR) 500 mg in a single pill. This combination provides comprehensive control of blood glucose by targeting multiple pathways, including insulin secretion, carbohydrate absorption, and insulin sensitivity.

This guide provides detailed insights into GLIMITERIS TRIO 0.5/0.2/500, including its composition, mechanism of action, uses, benefits, dosage, side effects, precautions, and frequently asked questions.

Introduction to GLIMITERIS TRIO 0.5/0.2/500

GLIMITERIS TRIO 0.5/0.2/500 is designed for patients with Type 2 Diabetes Mellitus who require dual or triple therapy for optimal blood sugar control. This combination tablet addresses:

  • Fasting blood sugar elevations

  • Postprandial glucose spikes

  • Insulin resistance

By combining three well-established antidiabetic agents, GLIMITERIS TRIO 0.5/0.2/500 helps achieve balanced, long-term glycaemic control, making it ideal for Indian patients with lifestyle-related diabetes.

Composition of GLIMITERIS TRIO 0.5/0.2/500

Each tablet contains:

  • Glimepiride 0.5 mg

  • Voglibose 0.2 mg

  • Metformin Hydrochloride (SR) 500 mg

This triple combination works synergistically to manage both fasting and postprandial blood glucose levels effectively.

Understanding the Key Ingredients

Glimepiride 0.5 mg

Glimepiride belongs to the sulfonylurea class. It helps lower blood sugar by:

  • Stimulating insulin release from pancreatic beta cells

  • Enhancing glucose uptake by tissues

  • Reducing postprandial blood sugar spikes

Glimepiride is effective at low doses and is well-tolerated in Indian patients.

Voglibose 0.2 mg

Voglibose is an alpha-glucosidase inhibitor that works in the gut to:

  • Delay carbohydrate breakdown into glucose

  • Slow absorption of glucose in the small intestine

  • Reduce post-meal blood sugar surges

It complements Glimepiride by targeting postprandial hyperglycaemia without overstimulating insulin secretion.

Metformin Hydrochloride (SR) 500 mg

Metformin is a biguanide and a first-line therapy for T2DM. It helps:

  • Reduce glucose production in the liver

  • Improve insulin sensitivity

  • Enhance glucose uptake by muscle and adipose tissue

  • Support weight management

The sustained-release (SR) formulation ensures stable blood sugar control throughout the day with fewer gastrointestinal side effects.

How GLIMITERIS TRIO 0.5/0.2/500 Works

GLIMITERIS TRIO 0.5/0.2/500 works through a triple mechanism:

  1. Glimepiride – Increases insulin secretion to manage fasting and post-meal glucose.

  2. Voglibose – Delays glucose absorption from meals to prevent spikes.

  3. Metformin SR – Reduces hepatic glucose production and improves insulin sensitivity.

The combination ensures comprehensive blood sugar control and helps improve HbA1c levels, which is critical for preventing diabetes-related complications.

Uses of GLIMITERIS TRIO 0.5/0.2/500 Tablet

Type 2 Diabetes Mellitus

GLIMITERIS TRIO 0.5/0.2/500 is primarily prescribed for patients who require triple therapy to control blood sugar.

Postprandial Hyperglycaemia

Voglibose helps manage sharp rises in blood sugar after meals, common in Indian dietary patterns.

Insulin Resistance

Metformin improves the body’s response to insulin, aiding better glucose utilization.

Prevention of Long-Term Complications

Effective glycaemic control reduces risks of:

  • Cardiovascular disease

  • Kidney damage

  • Nerve disorders

  • Eye complications

Patients with Obesity or Overweight

The Metformin component supports weight management, making this combination suitable for overweight diabetic patients.

Benefits of GLIMITERIS TRIO 0.5/0.2/500

Strong Glycaemic Control

Covers both fasting and postprandial glucose levels effectively.

Triple Mechanism for Maximum Efficacy

Targets insulin secretion, glucose absorption, and insulin resistance.

Low Risk of Hypoglycaemia

Voglibose and Metformin reduce the risk of low blood sugar compared to sulfonylurea monotherapy.

Weight-Friendly Therapy

Metformin helps maintain or reduce body weight.

Improved HbA1c

Supports long-term blood sugar management and reduces diabetes complications.

Convenient Once-Daily Dosing

Sustained-release Metformin and combination therapy improve adherence.

Suitable for Indian Diets

Helps manage blood sugar spikes after carbohydrate-rich meals.

Dosage of GLIMITERIS TRIO 0.5/0.2/500

Recommended Dosage

  • As prescribed by the doctor

  • Usually taken once or twice daily with meals

How to Take

  • Take the tablet with or immediately after meals

  • Swallow whole with water

  • Do not crush or chew

Dose Adjustment

The doctor may adjust the dose based on:

  • Blood sugar levels

  • Kidney function

  • Age

  • Tolerance and side effects

Missed Dose and Overdose

Missed Dose

  • Take as soon as you remember

  • Skip if close to the next dose

  • Do not double the dose

Overdose

Overdose can cause:

  • Low blood sugar (hypoglycaemia)

  • Gastrointestinal upset

  • Rarely, lactic acidosis

Seek immediate medical attention if severe symptoms occur.

Side Effects of GLIMITERIS TRIO 0.5/0.2/500

Most patients tolerate this combination well, though mild side effects may occur.

Common Side Effects

  • Nausea

  • Diarrhoea

  • Flatulence

  • Abdominal discomfort

Low Blood Sugar (Hypoglycaemia)

More likely if meals are skipped, excessive exercise occurs, or alcohol is consumed. Symptoms include:

  • Sweating

  • Dizziness

  • Tremors

  • Hunger

Rare but Serious Side Effects

  • Lactic acidosis (linked to Metformin SR)

  • Severe gastrointestinal distress

Seek immediate medical care if serious symptoms appear.

Precautions and Warnings

  • Kidney Impairment – Dose adjustment may be required.

  • Liver Problems – Use cautiously under supervision.

  • Elderly Patients – Monitor kidney function and hydration.

  • Pregnancy & Breastfeeding – Only use if prescribed by a doctor.

  • Alcohol – Avoid excessive consumption.

Drug Interactions

GLIMITERIS TRIO 0.5/0.2/500 may interact with:

  • Other antidiabetic medicines

  • Diuretics

  • Steroids

  • Blood pressure medications

  • Alcohol

Always inform your doctor about all medications and supplements.

Lifestyle Advice for Optimal Results

  • Follow a balanced diabetic diet

  • Limit high-carbohydrate and sugary foods

  • Exercise regularly

  • Monitor blood sugar levels at home

  • Maintain healthy body weight

  • Avoid smoking and excessive alcohol

Storage Instructions

  • Store below 25°C

  • Keep away from moisture and sunlight

  • Keep out of reach of children

Why Choose GLIMITERIS TRIO 0.5/0.2/500?

GLIMITERIS TRIO 0.5/0.2/500 offers:

  • Comprehensive glycaemic control

  • Dual blood sugar management for fasting and post-meal levels

  • Weight-friendly formulation

  • Convenient single-pill therapy

  • Proven safety and efficacy

It is a trusted choice for Indian patients requiring effective triple therapy for Type 2 Diabetes Mellitus.

Conclusion

GLIMITERIS TRIO 0.5/0.2/500 Tablet, combining Glimepiride 0.5 mg, Voglibose 0.2 mg, and Metformin Hydrochloride (SR) 500 mg, is an effective, well-tolerated, and convenient option for Type 2 Diabetes Mellitus. Its triple-action mechanism ensures optimal blood sugar control, reduces post-meal glucose spikes, and supports long-term metabolic health.

Frequently Asked Questions 

What is GLIMITERIS TRIO 0.5/0.2/500 used for?

It is used to treat Type 2 Diabetes Mellitus, especially when triple therapy is required.

Does GLIMITERIS TRIO 0.5/0.2/500 cause low blood sugar?

Risk is low with proper diet and adherence to dosage, but Glimepiride can occasionally cause hypoglycaemia.

Can this tablet help with weight management?

Yes, Metformin helps prevent weight gain and may support mild weight reduction.

Is it safe for long-term use?

Yes, under regular medical supervision.

Can elderly patients take this medicine?

Yes, with monitoring of kidney function and hydration.

If You Want To Purchase The Product Click Here.

We Have Our Diabetic Range .

Composition  Brand Name
Voglibose 0.3 mg, Glimepiride 2 mg & Metformin Hydrochloride 500 mg

GLIMITERIS TRIO 0.3

Voglibose 0.2 mg, Glimepiride 3 mg & Metformin Hydrochloride 500 mg
GLIMITERIS TRIO 0.2

 

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