furosemide and spironolactone tablets: overview ....

FRUSIP PLUS 20 

Furosemide (20 mg) & Spironolactone (50mg)

FRUSIP PLUS 20 is a powerful combination medication comprising Furosemide (20 mg) and Spironolactone (50 mg). This medication is widely used in the treatment of conditions associated with fluid retention and high blood pressure. Furosemide is a potent diuretic, while Spironolactone is an aldosterone antagonist that helps to maintain potassium levels. Together, they provide a synergistic effect that effectively manages edema and hypertension. This article delves into the uses, dosage, side effects, and pricing of FRUSIP PLUS 20, offering a thorough understanding of its benefits and precautions.

Uses

FRUSIP PLUS 20 is primarily indicated for:

1. Edema: This medication is highly effective in reducing fluid retention associated with congestive heart failure, liver cirrhosis, and nephrotic syndrome. By promoting diuresis, it helps to alleviate swelling and discomfort caused by excess fluid accumulation.

2. Hypertension: FRUSIP PLUS 20 is used in managing high blood pressure, especially in patients who have not responded adequately to monotherapy. The combination of Furosemide and Spironolactone helps to control blood pressure by reducing fluid volume and counteracting the effects of aldosterone.

3. Heart Failure: In patients with congestive heart failure, FRUSIP PLUS 20 helps to reduce the workload on the heart by decreasing fluid overload, thereby improving symptoms and preventing hospitalizations.

How It Works

FRUSIP PLUS 20 combines two active ingredients, each with distinct mechanisms of action:

• Furosemide (20 mg): A loop diuretic that acts on the ascending limb of the loop of Henle in the kidneys. It inhibits the reabsorption of sodium and chloride, leading to increased excretion of water, sodium, chloride, magnesium, and calcium. This results in significant diuresis, helping to reduce fluid overload in the body.

• Spironolactone (50 mg): An aldosterone antagonist that works by blocking the effects of aldosterone in the distal renal tubules. Aldosterone promotes the retention of sodium and water while excreting potassium. By inhibiting aldosterone, Spironolactone helps to reduce sodium and water retention while conserving potassium, balancing electrolyte levels and preventing hypokalemia.

Dosage

The dosage of FRUSIP PLUS 20 should be individualized based on the patient's condition and response to treatment. The typical starting dose is one tablet taken once daily, preferably in the morning to avoid nocturnal diuresis. In some cases, the dosage may be adjusted by the healthcare provider based on the severity of the condition and the patient's response.

• Adults: The usual dose is one tablet daily. The healthcare provider may adjust the dose based on therapeutic response and tolerance.

• Elderly: Dosage adjustments may be necessary in elderly patients due to potential age-related renal function decline. Careful monitoring is essential.

• Children: FRUSIP PLUS 20 is generally not recommended for pediatric use due to the lack of sufficient data on safety and efficacy.

Side Effects

Like all medications, FRUSIP PLUS 20 can cause side effects. Not everyone will experience these, but it is essential to be aware of potential adverse reactions. Common side effects include:

• Electrolyte Imbalance: Furosemide can cause imbalances in electrolytes, including low potassium, sodium, and magnesium levels. Regular monitoring of electrolyte levels is necessary.

• Dehydration: Excessive diuresis can lead to dehydration, characterized by symptoms such as dry mouth, thirst, and reduced urine output.

• Hypotension: The combined effect of Furosemide and Spironolactone can cause a significant drop in blood pressure, leading to dizziness, lightheadedness, or fainting.

• Gastrointestinal Disturbances: Some patients may experience nausea, vomiting, or diarrhea.

• Gynecomastia: Spironolactone can cause breast enlargement in males, a condition known as gynecomastia.

• Hyperkalemia: Although Spironolactone is potassium-sparing, in some cases, it can cause high potassium levels, especially when combined with other potassium-sparing medications or supplements.

Precautions

• Kidney Function: Regular monitoring of renal function is essential, as both Furosemide and Spironolactone can affect kidney function.

• Liver Function: Patients with liver disease should use FRUSIP PLUS 20 with caution, as impaired liver function can alter drug metabolism and excretion.

• Drug Interactions: FRUSIP PLUS 20 can interact with other medications, including ACE inhibitors, NSAIDs, and other diuretics. Inform your healthcare provider of all medications you are taking to avoid potential interactions.

• Pregnancy and Breastfeeding: Consult your healthcare provider before using FRUSIP PLUS 20 if you are pregnant or breastfeeding, as the safety of this medication in these conditions has not been fully established.

Price

The price of FRUSIP PLUS 20 can vary based on the manufacturer, location, and pharmacy. On average, the cost for a month's supply (30 tablets) ranges between INR 150 to INR 300. Prices may differ, so it is advisable to check with local pharmacies or online retailers for the best deals.

Conclusion

FRUSIP PLUS 20 is a highly effective medication for managing conditions associated with fluid retention and high blood pressure. By combining the potent diuretic effects of Furosemide with the potassium-sparing action of Spironolactone, it offers a comprehensive solution for edema and hypertension. However, it is essential to use this medication under the guidance of a healthcare provider, with regular monitoring of electrolyte levels and kidney function. If you experience any side effects or have concerns about the medication, consult your healthcare provider promptly. With proper use and precautions, FRUSIP PLUS 20 can significantly improve symptoms and enhance the quality of life for patients with fluid retention and hypertension. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology.

For further information 

Email: info@sterispharma.com /  contact@sterispharma.com

Call/WhatsApp:  7877551268, 7849827488 

BUY NOW