ACOTIAMATE ER 300: Uses, Dosage, Side Effects, Composition , ETC......

Introduction

ACOTIAMATE ER 300 is a once-daily, extended-release tablet containing Acotiamide 300 mg, specially formulated to manage functional dyspepsia — a chronic condition affecting the upper digestive tract. Unlike acid-suppressive therapy, Acotiamide works by enhancing gastric motility and improving gastric accommodation, addressing the core pathophysiology of dyspepsia.

What is Acotiamide?

Acotiamide is a gastroprokinetic drug, also known as a motility modulator, primarily used to treat functional gastrointestinal disorders. It differs from antacids or PPIs (proton pump inhibitors) because it doesn't act on stomach acid. Instead, it targets the muscular function of the stomach, making it particularly useful for non-ulcer dyspepsia.

Acotiamide Tablet Uses (Clinical Applications)

Acotiamide 300 mg ER tablets are indicated for the treatment of:

• Functional dyspepsia (FD)

• Postprandial distress syndrome (PDS)

• Post-meal fullness, bloating, and upper abdominal discomfort

• Patients with delayed gastric emptying

• Cases unresponsive to traditional antacid or PPI therapy

• Gastrointestinal motility disorders in select patient profiles

Acotiamide tablets 100mg or 300mg are especially helpful for people who complain of gas, abdominal heaviness, and loss of appetite after meals — often with normal endoscopy reports.

Acotiamide Mechanism of Action (Pharmacodynamics)

The mechanism of action of Acotiamide is centered around enhancing acetylcholine availability. Acetylcholine is a neurotransmitter that stimulates smooth muscle movement in the gastrointestinal (GI) tract.

• Acotiamide inhibits acetylcholinesterase, the enzyme that breaks down acetylcholine

• This increases acetylcholine levels in the enteric nervous system

• Result: enhanced gastric contraction, better food propulsion, and improved gastric emptying

• It also helps the stomach adapt its shape and size to accommodate food, reducing discomfort and bloating

In short, Acotiamide 300 mg helps the stomach work more efficiently, not just control acid.

Acotiamide Dosage and Administration

The Acotiamide dosage depends on the formulation:

• For ER (Extended Release):
  300 mg tablet once daily, preferably before the main meal of the day

• For standard immediate-release tablets:
  100 mg three times daily before meals

ACOTIAMATE ER 300 provides the benefit of once-daily convenience with all-day symptom control.

Always take under physician supervision and avoid missing doses for consistent relief.

Who Can Benefit from Acotiamide 300 mg?

This medication is suitable for:

• Adults aged 18 to 65+ suffering from chronic bloating or indigestion

• Patients with normal endoscopy but persistent dyspeptic symptoms

• Those who do not respond to traditional GERD or acid-suppressive therapy

• Individuals with slow gastric motility, especially after surgery or certain medications

Safety Profile and Tolerability

Acotiamide 300 mg is generally well-tolerated. Commonly reported side effects are mild and transient, such as:

• Headache

• Nausea

• Constipation or loose motion

• Fatigue (rare)

No significant sedative effect, hormonal changes, or addictive potential has been noted. However, pregnant or breastfeeding women should consult a doctor before use.

Frequently Asked Questions (FAQs)

1. What are the most common Acotiamide tablet uses?
Acotiamide tablets are mainly used to treat functional dyspepsia, post-meal bloating, and gastric discomfort.

2. What is the correct Acotiamide dosage?
For extended release tablets, the standard dosage is 300 mg once daily before meals. Immediate-release versions require 100 mg three times daily.

3. How does Acotiamide work in the body?
It enhances gastric motility by increasing acetylcholine levels in the stomach muscles, helping food move through the digestive tract more effectively.

4. Is Acotiamide safe for long-term use?
Yes, it is generally safe when used under medical supervision for prolonged periods in patients with chronic symptoms.

5. Can Acotiamide help with GERD or acidity?
Not directly. Acotiamide is for functional motility-related disorders, not acid reflux. However, it may help in cases where bloating and indigestion coexist with GERD symptoms.

Conclusion

ACOTIAMATE ER 300 delivers sustained, effective relief from functional dyspepsia by directly improving gastric muscle activity and post-meal digestion. Its once-daily dosing, excellent safety profile, and action on the underlying cause of dyspepsia make it an ideal choice for patients needing long-term gastric support.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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