Acotiamide 300 mg | ACOTIAMATE ER 300

ACOTIAMATE ER 300 is manufactured and marketed by Steris Healthcare Pvt. Ltd. It's a single-ingredient extended-release tablet containing 300mg of acotiamide, a prokinetic medicine specifically designed to relieve the uncomfortable, often frustrating symptoms of functional dyspepsia. Below you'll find complete product information, a full breakdown of acotiamide's uses at this strength, how it works, why it's genuinely different from other digestive medicines, correct dosing, safety details, and a clear path to ordering it.

Product Information

Why It's Important

Functional dyspepsia, despite showing no structural abnormality on standard testing, is a genuinely disruptive condition — persistent post-meal discomfort can affect eating enjoyment, nutrition, work concentration, and overall quality of life in ways that are easy for others to underestimate. Acotiamide's importance in this picture comes down to a few specific points:

• It directly targets the underlying motility problem in functional dyspepsia, rather than simply reducing stomach acid, which is often the wrong target for this specific condition
• Many patients with functional dyspepsia have tried and had limited success with standard acid-suppressing medicines before receiving a more accurate diagnosis and being offered a prokinetic option like acotiamide
• Persistent postprandial fullness and early satiety can lead patients to unconsciously reduce their food intake over time, which can affect nutrition and weight if left unaddressed
• Having a medicine specifically studied and developed for this exact symptom pattern — rather than adapted from another gastrointestinal condition — reflects a more precise, evidence-based approach to a condition that's historically been difficult to treat effectively

For patients who've struggled with persistent post-meal fullness and bloating despite trying standard digestive remedies, acotiamide offers a genuinely different, more targeted mechanism worth discussing with a gastroenterologist.

Key Benefits 

What Are the Benefits of Acotiamide Tablets?

• Targets the actual mechanism behind functional dyspepsia – Addresses impaired stomach motility directly, rather than acid production, which is often not the underlying issue in this condition.
• Relief from postprandial fullness and early satiety – Specifically studied for these core, often difficult-to-treat functional dyspepsia symptoms.
• A genuine option after acid-suppressing medicines fall short – Offers a different mechanism for patients whose symptoms haven't responded adequately to standard antacids or acid reducers.
• Extended-release formulation – Designed for once-daily dosing convenience, supporting easier adherence to a consistent treatment routine.
• Generally well-tolerated profile – Acotiamide is not associated with the same acid-rebound or long-term acid-suppression concerns that come with prolonged use of some other digestive medicines.
• Manufactured under WHO-GMP standards – Produced by Steris Healthcare, a WHO-GMP and ISO 9001:2018 certified pharmaceutical manufacturer, supporting consistent quality and safety compliance.

Acotiamide Tablets Uses and Mechanism of Action

Uses: Acotiamide Tablets 300mg is used for the management of functional dyspepsia, specifically addressing postprandial fullness, early satiety, and upper abdominal bloating, as determined by the treating doctor after appropriate evaluation to rule out other structural causes of these symptoms.

Mechanism of Action: Acotiamide works as a prokinetic agent through a distinctive dual mechanism. It inhibits acetylcholinesterase, an enzyme that would otherwise break down acetylcholine — a neurotransmitter essential for stimulating stomach muscle contraction and coordinated movement. By preserving acetylcholine activity, acotiamide enhances the stomach's ability to contract and empty its contents into the small intestine more efficiently. Additionally, acotiamide blocks certain presynaptic muscarinic autoreceptors (M1 and M2 receptors) that would otherwise limit acetylcholine release, further supporting improved gastric motility. Together, these actions help the stomach relax appropriately after eating (a process called gastric accommodation) and empty its contents in a more coordinated, timely way — directly addressing the underlying motility dysfunction believed to drive functional dyspepsia symptoms, rather than simply reducing stomach acid.

Side Effects of Acotiamide Tablets

Common, generally mild side effects can include:

• Diarrhea or loose stools
• Nausea
• Headache
• Mild abdominal discomfort
• Constipation (less commonly)

Precautions & Warnings

• This medicine is specifically intended for functional dyspepsia; persistent or worsening digestive symptoms should always be properly evaluated by a doctor to rule out other underlying conditions before or during treatment.
• Since this is an extended-release formulation, swallow the tablet whole — do not crush, chew, or split it, as this can affect how the medicine is released and absorbed.
• Inform your doctor of all other medicines being taken, to check for potential interactions, particularly other medicines affecting gastrointestinal motility.
• Use with caution in patients with significant liver impairment.
• Not recommended during pregnancy or breastfeeding unless specifically directed by a doctor, given limited safety data in these populations.
• If symptoms do not improve within the timeframe your doctor has outlined, follow up promptly rather than continuing treatment indefinitely without reassessment.
• Store in a cool, dry place, protected from light and moisture, and keep out of reach of children.

Frequently Asked Questions 

Where can I buy Acotiamide 300 mg online?

Acotiamide 300 mg should be purchased from a licensed and authorized pharmacy. Availability may vary depending on your location, manufacturer, and prescription requirements.

What is the price of Acotiamide 300 mg?

The price depends on the manufacturer, pack size, pharmacy, and location. Contact a licensed pharmacy or authorized supplier for current pricing.

Can I order Acotiamide 300 mg online?

Where permitted by local regulations, Acotiamide 300 mg may be ordered through a licensed online pharmacy. A prescription may be required depending on local regulations.

Is Acotiamide 300 mg available from Steris Healthcare?

Availability may depend on the specific product, manufacturer, formulation, and location. Contact Steris Healthcare or check its current product catalogue to confirm availability.

What is Acotiamide 300 mg used for?

Acotiamide is a gastrointestinal motility medicine used to treat symptoms associated with functional dyspepsia, such as post-meal fullness, upper abdominal discomfort, and early satiety. It works by improving gastric motility and supporting normal gastrointestinal function.

What is the composition of Acotiamide 300 mg?

The active ingredient is acotiamide 300 mg, depending on the specific formulation. Inactive ingredients can vary by manufacturer, so refer to the product packaging or prescribing information for the complete composition.

Is a prescription required?

Acotiamide may be a prescription medicine, depending on the country and product. Follow local regulations and use it under the guidance of a qualified healthcare professional.

How should Acotiamide 300 mg be taken?

Take Acotiamide exactly as prescribed by your doctor. The appropriate dose and timing depend on the formulation and your individual condition. Do not change the dose or stop treatment without medical advice.

What should I know before buying Acotiamide 300 mg?

Before purchasing, verify the strength, formulation, manufacturer, expiry date, packaging, and pharmacy credentials. Tell your healthcare professional about other medicines you take and any relevant gastrointestinal or other medical conditions.

How can I order Acotiamide 300 mg online?

If online purchasing is permitted in your location, use a licensed online pharmacy and provide a valid prescription when required. Confirm the product strength and formulation before ordering, and avoid unverified websites selling medicines without appropriate safeguards.