VOGLIGOLD G3 M0.3 uses, benifits, side effects and more information..

Jul 06, 2024

VOGLIGOLD G3 M0.3

Voglibose 0.3 mg, Glimepiride 3 mg & Metformin Hydrochloride 500 mg

VOGLIGOLD G3 M0.3 is a combination medication used in the management of type 2 diabetes mellitus. It contains three active ingredients: Voglibose 0.3 mg, Glimepiride 3 mg, and Metformin Hydrochloride 500 mg. This medication works synergistically to help control blood glucose levels, offering a multifaceted approach to diabetes management.

Components and Their Functions

Voglibose 0.3 mg

Voglibose is an alpha-glucosidase inhibitor that helps to control postprandial blood glucose spikes. It works by delaying the absorption of carbohydrates from the intestines, thereby reducing the rise in blood sugar levels after meals. This makes Voglibose particularly effective in managing post-meal hyperglycemia.

Glimepiride 3 mg

Glimepiride is a sulfonylurea class medication that helps increase insulin secretion from the pancreas. By stimulating the pancreatic beta cells, Glimepiride enhances the body's ability to lower blood sugar levels. It is known for its effectiveness in reducing fasting blood glucose levels and its relatively lower risk of causing hypoglycemia compared to other sulfonylureas.

Metformin Hydrochloride 500 mg

Metformin is a biguanide that works primarily by decreasing hepatic glucose production and increasing insulin sensitivity in peripheral tissues. It is the first-line medication for type 2 diabetes due to its efficacy in lowering HbA1c levels and its beneficial effects on weight and cardiovascular outcomes. Metformin also helps in reducing the absorption of glucose from the intestines.

Indications

VOGLIGOLD G3 M0.3 is indicated for patients with type 2 diabetes mellitus who require multiple mechanisms of action to control their blood glucose levels. It is particularly useful for those who have not achieved adequate glycemic control with diet, exercise, and monotherapy or dual therapy with oral antidiabetic agents.

Dosage and Administration

Dosage

The typical dose of VOGLIGOLD G3 M0.3 is one tablet taken once daily with the first meal of the day.  It is crucial to follow the healthcare provider's instructions regarding the dosage and to not alter the dose without medical advice.

Administration

  • Swallow Whole: The tablet should be swallowed whole with water and not crushed or chewed.
  • Consistent Timing: Taking the medication at the same time each day helps maintain consistent blood glucose levels.

Mechanism of Action

VOGLIGOLD G3 M0.3 employs a triple mechanism of action to achieve optimal glycemic control:

  1. Glimepiride: Stimulates insulin release from pancreatic beta cells, lowering blood glucose levels.
  2. Metformin: Reduces hepatic glucose production and increases peripheral insulin sensitivity.

This combination targets multiple pathways involved in glucose regulation, making it an effective option for comprehensive diabetes management.

Benefits of VOGLIGOLD G3 M0.3

Improved Glycemic Control

The combination of Voglibose, Glimepiride, and Metformin offers superior glycemic control by addressing fasting, postprandial, and overall blood glucose levels. This helps in achieving target HbA1c levels more effectively than monotherapy or dual therapy.

Reduced Risk of Complications

Effective management of blood glucose levels with VOGLIGOLD G3 M0.3 helps reduce the risk of diabetes-related complications such as neuropathy, nephropathy, retinopathy, and cardiovascular diseases.

Weight Management

Metformin in the combination helps in weight management by reducing appetite and promoting slight weight loss or weight neutrality, which is beneficial for overweight or obese patients with type 2 diabetes.

Side Effects

Like all medications, VOGLIGOLD G3 M0.3 may cause side effects, although not everyone experiences them. Common side effects include:

  • Gastrointestinal Issues: Nausea, vomiting, diarrhea, abdominal pain, and flatulence, primarily due to Metformin and Voglibose.
  • Hypoglycemia: Risk of low blood sugar levels, especially if combined with other antidiabetic medications or insulin.
  • Allergic Reactions: Rash, itching, or swelling, indicating an allergic response to any of the components.

Precautions and Warnings

Hypoglycemia

Patients should be educated on recognizing the symptoms of hypoglycemia (e.g., dizziness, sweating, palpitations) and how to manage it. 

Renal Function

Metformin can affect renal function, so it is important to assess kidney function before initiating treatment and periodically thereafter. VOGLIGOLD G3 M0.3 should be used with caution in patients with renal impairment.

Hepatic Function

Patients with liver disease should use this medication with caution, as Metformin can affect liver function and may increase the risk of lactic acidosis.

Heart Failure

Patients with heart failure should be monitored closely, as Metformin can exacerbate the condition in some cases.

Drug Interactions

VOGLIGOLD G3 M0.3 may interact with other medications, which can affect its efficacy and safety. Some notable interactions include:

  • Other Antidiabetic Drugs: Increased risk of hypoglycemia when used with insulin or other sulfonylureas.
  • Diuretics: Can affect blood glucose levels and renal function.
  • Beta-Blockers: May mask the symptoms of hypoglycemia.
  • Corticosteroids: Can increase blood glucose levels, reducing the efficacy of VOGLIGOLD G3 M0.3.

Patients should inform their healthcare provider about all medications they are taking, including over-the-counter drugs and supplements, to avoid potential interactions.

Conclusion

VOGLIGOLD G3 M0.3 is a potent combination medication for managing type 2 diabetes mellitus, offering the benefits of Voglibose, Glimepiride, and Metformin. Its multi-faceted approach provides comprehensive glycemic control, reduces the risk of complications, and aids in weight management. However, it is essential to use this medication under the guidance of a healthcare provider, with regular monitoring and adherence to prescribed dosages. By doing so, patients can achieve better diabetes management and improve their overall quality of life. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology. 

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp:  7877551268, 7849827488  

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