Vildagliptin 50 mg + Metformin Hydrochloride 500 mg

Introduction

VILDIABATE M 500 is an advanced anti-diabetic medication designed to manage type 2 diabetes mellitus (T2DM) effectively. This combination tablet contains Metformin (500mg) SR (Sustained Release) and Vildagliptin (50mg), two potent agents that work together to regulate blood sugar levels. It is particularly beneficial for individuals struggling with poor glycemic control despite lifestyle modifications. This article explores the uses, benefits, dosage, side effects, precautions, and other essential information related to VILDIABATE M 500.

Key Ingredients

1. Metformin (500mg) SR

• Biguanide class medication that improves insulin sensitivity and reduces glucose production in the liver.

• Helps lower fasting blood glucose (FBG) and postprandial blood glucose (PPBG) levels.

• Does not cause hypoglycemia when used alone.

• The SR (Sustained Release) formulation ensures a steady effect, reducing the chances of gastric side effects.

2. Vildagliptin (50mg)

• Dipeptidyl Peptidase-4 (DPP-4) inhibitor that enhances incretin hormone function, leading to improved insulin secretion and reduced glucagon levels.

• Reduces post-meal glucose spikes effectively.

• Helps preserve pancreatic beta-cell function over time.

• Does not contribute to weight gain, making it ideal for overweight diabetic patients.

How Does VILDIABATE M 500 Work?

The combination of Metformin and Vildagliptin targets multiple pathways involved in diabetes management:

1. Metformin reduces hepatic glucose production and increases insulin sensitivity.

2. Vildagliptin improves insulin secretion from pancreatic beta cells and lowers glucagon production, which reduces excessive glucose release from the liver.

3. Together, they provide a synergistic effect, ensuring optimal glycemic control without causing significant hypoglycemia.

Key Benefits of VILDIABATE M 500

• Effectively lowers HbA1c levels.

• Enhances insulin sensitivity and reduces insulin resistance.

• Controls fasting and postprandial blood sugar levels.

• Minimizes gastrointestinal side effects due to the SR formulation of Metformin.

• Prevents beta-cell exhaustion, thereby delaying diabetes progression.

• Reduces the risk of diabetes-related complications such as neuropathy, nephropathy, and cardiovascular diseases.

• Does not cause significant weight gain or hypoglycemia when used correctly.

Dosage and Administration

• Recommended Dose: One tablet daily, preferably with food, as directed by the healthcare provider.

• Maximum Dose: Can be adjusted to two tablets daily, depending on individual patient response and physician recommendation.

• Administration: Swallow the tablet whole with a glass of water. Do not crush or chew.

• Missed Dose: If a dose is missed, take it as soon as possible unless it is almost time for the next dose. Do not double the dose to compensate.

Possible Side Effects

While VILDIABATE M 500 is well-tolerated, some individuals may experience mild to moderate side effects:

Common Side Effects

• Nausea and vomiting

• Diarrhea or stomach discomfort

• Headache and dizziness

• Fatigue or weakness

• Metallic taste in the mouth

Rare but Serious Side Effects

• Lactic acidosis (a rare but serious complication of Metformin, particularly in patients with kidney issues).

• Pancreatitis (severe abdominal pain, nausea, vomiting).

• Hypoglycemia (low blood sugar, especially when combined with other diabetes medications).

• Liver enzyme abnormalities (monitoring is required in some cases).

• Allergic reactions (rash, itching, swelling, or difficulty breathing).

Precautions and Warnings

Who Should Avoid Taking VILDIABATE M 500?

• Patients with severe kidney or liver impairment.

• Individuals with a history of pancreatitis.

• People with known allergies to Metformin, Vildagliptin, or any excipients.

• Patients with severe heart disease or a recent heart attack.

• Individuals undergoing surgery or severe stress conditions.

Special Precautions

• Monitor renal function before and during treatment to avoid Metformin-related complications.

• Alcohol consumption should be limited as it may increase the risk of lactic acidosis.

• Regular liver function tests are advisable in long-term users of Vildagliptin.

• Pregnant or breastfeeding women should consult their healthcare provider before use.

Drug Interactions

• Sulfonylureas & Insulin: Increased risk of hypoglycemia.

• Diuretics & NSAIDs: May affect kidney function and increase the risk of lactic acidosis.

• Beta-blockers: Can mask symptoms of hypoglycemia.

• Corticosteroids & Thyroid hormones: May reduce the effectiveness of VILDIABATE M 500.

Price and Availability in India

• The price of VILDIABATE M 500 varies depending on the brand and pharmacy location.

• Generally available at ₹200 - ₹500 per strip of 10 tablets.

• Can be purchased at local pharmacies or online medicine stores with a doctor’s prescription.

Conclusion

VILDIABATE M 500 is a highly effective oral anti-diabetic medication that combines Metformin (500mg) SR and Vildagliptin (50mg) to improve glycemic control in type 2 diabetes mellitus. With its dual-action mechanism, it helps regulate blood sugar levels, improves insulin sensitivity, and protects beta-cell function. Patients using this medication should follow proper dosage instructions, maintain a healthy diet and lifestyle, and regularly monitor their blood glucose levels to achieve the best results. Always consult a healthcare professional before starting or altering diabetes treatment.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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