Rifaximin (400mg) ''''

Introduction

RIFAXIKEM-400 Tablet contains Rifaximin 400 mg, a non-systemic antibiotic primarily used to treat gastrointestinal infections. Manufactured under stringent quality standards, this tablet offers a broad-spectrum antibacterial effect with minimal systemic absorption, making it safe and effective for intestinal infections like Traveler’s Diarrhea, Irritable Bowel Syndrome with Diarrhea (IBS-D), and Hepatic Encephalopathy.

Composition

• Rifaximin – 400 mg

Rifaximin is a rifamycin-class antibiotic that works locally in the gut without entering the bloodstream in significant amounts, thus minimizing side effects and resistance issues.

Mechanism of Action

Rifaximin inhibits bacterial RNA synthesis by binding to the beta-subunit of bacterial DNA-dependent RNA polymerase. It is minimally absorbed from the gastrointestinal tract, ensuring localized action with reduced risk of systemic toxicity.

Indications

RIFAXIKEM-400 is indicated for the treatment of:

• Traveler’s Diarrhea caused by non-invasive strains of Escherichia coli

• Irritable Bowel Syndrome with Diarrhea (IBS-D)

• Hepatic Encephalopathy – reduces the risk of recurrent episodes

• Small Intestinal Bacterial Overgrowth (SIBO) – off-label use

• Bowel preparation before colonoscopy – off-label

Benefits of RIFAXIKEM-400 Tablet

• Local Action in the Gut

Minimal systemic absorption reduces the risk of systemic side effects.

• Effective Against a Broad Range of GI Pathogens

Covers both Gram-positive and Gram-negative bacteria causing intestinal infections.

• Reduces Recurrence in Hepatic Encephalopathy

Proven to lower ammonia-producing bacteria, thereby preventing neurotoxic symptoms.

• Improves IBS-D Symptoms

Alleviates bloating, abdominal pain, and diarrhea in patients with IBS-D.

• Well Tolerated

Safe for prolonged use in liver-impaired patients under supervision.

Dosage and Administration

• Traveler’s Diarrhea: 400 mg orally three times daily for 3 days

• Hepatic Encephalopathy: 550 mg twice daily (adjust dose under medical supervision)

• IBS-D: 550 mg three times daily for 14 days (as per physician’s advice)

Note: Always follow your doctor’s instructions regarding dosage and duration.

Side Effects

RIFAXIKEM-400 is generally well-tolerated. Possible side effects include:

• Nausea

• Flatulence

• Abdominal pain

• Headache

• Constipation

Serious allergic reactions are rare but require immediate medical attention.

Precautions

• Avoid use in patients with severe hepatic impairment (Child-Pugh C) unless prescribed.

• Not recommended for diarrhea with fever or bloody stools.

• Avoid in known hypersensitivity to rifamycin derivatives.

• Not suitable for systemic infections due to poor absorption.

• Pregnant or breastfeeding women should consult a physician before use.

Why Choose RIFAXIKEM-400?

RIFAXIKEM-400 by Steris Healthcare is a high-quality gastrointestinal antibiotic that:

• Offers targeted action with minimal systemic side effects

• Manufactured in WHO-GMP certified facilities

• Ensures consistent potency and quality

• Trusted by healthcare professionals nationwide

Frequently Asked Questions (FAQs)

Q1. Can RIFAXIKEM-400 be used for bloating and IBS symptoms?

Yes, Rifaximin has been clinically shown to reduce bloating and diarrhea in patients with IBS-D.

Q2. Does Rifaximin cause resistance?

Rifaximin has a low risk of resistance due to its poor systemic absorption and local action in the gut.

Q3. How fast does RIFAXIKEM-400 work?

For Traveler’s Diarrhea, symptom relief is usually observed within 24 to 48 hours of starting treatment.

Q4. Can it be taken with probiotics?

Yes, combining Rifaximin with probiotics can enhance gut flora restoration post-treatment.

Conclusion

RIFAXIKEM-400 (Rifaximin 400 mg) is a reliable and safe option for managing various gastrointestinal infections. Its targeted action, minimal absorption, and excellent safety profile make it ideal for both short-term and long-term therapeutic regimens, especially in conditions like Traveler’s Diarrhea, IBS-D, and Hepatic Encephalopathy.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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