Rasagiline 0.1mg"'"'"'
Oct 10, 2023
Rasagiline (1 mg)
Rasagail 1.0
Rasagail 1.0 is a brand name for Rasagiline 1mg, a medication primarily used in the management of Parkinson's disease and Parkinson's disease symptoms. Rasagiline belongs to a class of drugs known as monoamine oxidase-B (MAO-B) inhibitors. By increasing the levels of certain neurotransmitters in the brain, Rasagiline helps improve the motor functions of individuals suffering from Parkinson’s disease. This article will provide an in-depth look at the uses, recommended dosages, possible side effects, and precautions related to Rasagiline 1mg.
What is Rasagail 1.0 (Rasagiline 1mg)?
Rasagail 1.0 contains Rasagiline 1mg as the active ingredient. It is an MAO-B inhibitor, which works by selectively inhibiting the enzyme monoamine oxidase type B (MAO-B) in the brain. This enzyme is responsible for breaking down dopamine, a neurotransmitter that plays a key role in regulating movement and mood. By inhibiting MAO-B, Rasagiline helps to preserve dopamine levels in the brain, leading to improvements in the motor symptoms of Parkinson's disease, such as tremors, stiffness, and bradykinesia (slowness of movement).
Rasagiline is typically prescribed as an adjunct therapy to levodopa, the primary treatment for Parkinson’s disease, or as a monotherapy in the early stages of the disease.
Uses of Rasagiline (1mg)
Rasagiline 1mg is primarily used for the following purposes:
1. Parkinson’s Disease Treatment
Rasagiline is commonly prescribed to help manage the symptoms of Parkinson’s disease. In patients with Parkinson’s, the brain’s ability to produce dopamine is compromised, leading to the characteristic motor symptoms of the disease—tremors, stiffness, difficulty initiating movement, and postural instability. By inhibiting the breakdown of dopamine, Rasagiline increases the amount of available dopamine in the brain, improving these symptoms.
- Monotherapy: In early stages of Parkinson's disease, Rasagiline 1mg may be used alone (monotherapy) to help alleviate symptoms.
- Adjunct to Levodopa: In more advanced stages, Rasagiline is often used in combination with levodopa or levodopa-carbidopa to help enhance the effects of levodopa and reduce the "wearing off" phenomenon, where levodopa’s effectiveness diminishes before the next dose.
2. Neuroprotective Effects
There is some evidence to suggest that Rasagiline may offer neuroprotective benefits in Parkinson’s disease, meaning it may help protect brain cells from the damage caused by the disease. However, this potential benefit is still under investigation and is not the primary reason for prescribing the medication.
3. Adjunct Treatment for Dementia (Off-label Use)
In some cases, Rasagiline may be used off-label to improve cognitive symptoms in conditions like Alzheimer’s disease and dementia. However, this is not a primary indication, and more research is needed to support its effectiveness in these areas.
Rasagiline Dosage
The typical dosage of Rasagiline 1mg is as follows:
-
Initial Dose: For most patients, the typical starting dose is 1 mg once daily. This is generally sufficient to provide therapeutic benefits in managing Parkinson’s disease symptoms.
-
Maintenance Dose: In most cases, the dose is maintained at 1 mg daily. Increasing the dose is generally not necessary or recommended, as higher doses may not offer additional benefits and could increase the risk of side effects.
-
Combination Therapy: When Rasagiline is used in combination with levodopa for advanced Parkinson’s disease, the dose of Rasagiline typically remains at 1 mg daily. Levodopa doses may be adjusted based on the patient’s needs.
Special Considerations:
- Renal or Hepatic Impairment: Patients with liver issues, particularly those with liver disease, may need adjusted dosing or closer monitoring while on Rasagiline.
- Elderly Patients: For older patients, Rasagiline is typically well-tolerated, but doctors may monitor for any adverse effects or adjust the dosage based on response.
It is essential to take Rasagiline exactly as prescribed by a healthcare provider. Rasagiline should be taken once daily, with or without food. It should not be taken in larger amounts or for longer periods than recommended, as this can increase the risk of side effects.
Side Effects of Rasagiline 1mg
As with any medication, Rasagiline 1mg can cause side effects, although not everyone will experience them. The most common and serious side effects of Rasagiline include:
Common Side Effects:
- Headache: One of the most common side effects reported by patients taking Rasagiline.
- Dizziness or Lightheadedness: Rasagiline can sometimes cause dizziness, particularly when standing up quickly. This is known as orthostatic hypotension and can lead to fainting.
- Insomnia: Difficulty sleeping can occur in some individuals.
- Nausea: Mild nausea or upset stomach is a relatively common side effect.
Serious Side Effects:
While rare, there are some serious side effects associated with Rasagiline that require immediate medical attention:
- Serotonin Syndrome: When Rasagiline is combined with other medications that increase serotonin levels, such as antidepressants (SSRIs, SNRIs) or triptans, there is a risk of serotonin syndrome, a potentially life-threatening condition. Symptoms include confusion, agitation, hallucinations, fever, sweating, muscle rigidity, and rapid heart rate.
- Hypertension (High Blood Pressure): Rasagiline may interact with certain foods (like aged cheeses or cured meats) and medications (such as decongestants), leading to hypertensive crises, a dangerous spike in blood pressure.
- Allergic Reactions: Some individuals may experience allergic reactions such as rash, itching, swelling, or difficulty breathing.
- Hallucinations or Delusions: Although rare, some Parkinson’s disease patients on Rasagiline may experience psychiatric side effects, including hallucinations or delusions.
Precautions and Interactions
Before starting Rasagiline 1mg, it is important to discuss any pre-existing medical conditions with your healthcare provider. Some conditions that may require special attention include:
- Liver Disease: Since Rasagiline is metabolized by the liver, patients with liver dysfunction may need a lower dose or additional monitoring.
- Cardiovascular Issues: If you have a history of heart disease, arrhythmias, or high blood pressure, your doctor will assess whether Rasagiline is appropriate for you.
- Pregnancy and Breastfeeding: Rasagiline is not recommended during pregnancy unless absolutely necessary, and its safety during breastfeeding has not been well established. Always consult a doctor before taking Rasagiline during pregnancy or while breastfeeding.
Conclusion
Rasagail 1.0 (Rasagiline 1mg) is a highly effective treatment for Parkinson’s disease, providing symptomatic relief by increasing dopamine levels in the brain. Whether used alone or in combination with other Parkinson’s medications, Rasagiline can significantly improve motor function, reducing the debilitating effects of Parkinson's disease. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology.
For further information
Email: info@sterispharma.com / contact@sterispharma.com
Call/WhatsApp: 7877551268, 7849827488
Recent Post

Empagliflozin and Metformin 12.5 mg Tablet: View Uses, Benefits, Dosage and Side Effects.

Antiseptic Healing with Povidone-Iodine Ointment USP

Flupirtine Maleate 100mg Tablet: FLUREPTIN 100 In Steris Healthcare Pvt Ltd.

STABLE SUNSCREEN 50 LOTION: Expert Solution For Sunscreen Protection.

Clobetasol, Neomycin & Miconazole Nitrate Cream for Skin Infections

Benfotiamine, Alpha Lipoic Acid, Inositol, Mecobalamin, Folic Acid, Chromium and Selenium Capsules.

Dydrogesterone 10 mg in DABROSTON 10: A Key Treatment for Menstrual Irregularities and Pregnancy Support

Iguratimod 25 mg – IBRUNITIME 25: Effective Solution for Rheumatoid Arthritis and Joint Inflammation

Alpha Galactosidase, Lipase, Alpha Amylase, Protease and Lactase Capsules.

Multi Enzyme Complex Probiotic Capsule: PYLODIGEST PRO