Pioglitazone 15 mg

Introduction

Piosteris 15 contains Pioglitazone (15mg), an oral anti-diabetic medication that belongs to the thiazolidinedione (TZD) class. It is widely used in the management of type 2 diabetes mellitus (T2DM) to help control blood sugar levels by improving insulin sensitivity. This medication is often prescribed either as a monotherapy or in combination with other anti-diabetic drugs, such as metformin or sulfonylureas.

In this article, we will explore the mechanism of action, benefits, dosage, side effects, precautions, drug interactions, and other essential details related to Piosteris 15.

Key Ingredients

• Pioglitazone Hydrochloride (15mg) – A potent insulin-sensitizing agent that reduces insulin resistance in muscle, liver, and adipose tissues, helping to lower blood glucose levels effectively.

How Does Piosteris 15 Work?

Pioglitazone (15mg) acts by targeting peroxisome proliferator-activated receptor-gamma (PPAR-γ) in fat cells. This results in:

1. Enhanced insulin sensitivity – Improves glucose uptake in muscles and liver.

2. Reduced glucose production – Lowers hepatic glucose output.

3. Better lipid metabolism – Helps control cholesterol levels by reducing triglycerides and increasing HDL cholesterol (good cholesterol).

4. Reduced inflammation – Decreases inflammation-related insulin resistance.

Key Benefits of Piosteris 15

• Effective blood sugar control – Helps in lowering fasting blood glucose and HbA1c levels.

• Reduces insulin resistance – Enhances the body’s response to insulin.

• Weight-neutral effect – Unlike some anti-diabetic medications, Piosteris 15 does not promote significant weight gain.

• Cardiovascular benefits – May improve lipid profiles and reduce the risk of cardiovascular diseases.

• Combination therapy potential – Can be used alongside other anti-diabetic drugs for better glycemic control.

Who Should Take Piosteris 15?

• Patients diagnosed with type 2 diabetes mellitus (T2DM) who require better glycemic control.

• Individuals with insulin resistance and metabolic syndrome.

• Patients needing an alternative to metformin due to intolerance or contraindications.

Dosage and Administration

• Standard Dose: Piosteris 15 (Pioglitazone 15mg) is usually taken once daily, with or without food.

• Combination Therapy: Can be combined with metformin, sulfonylureas, or DPP-4 inhibitors based on a doctor’s recommendation.

• Maximum Dose: The dose may be adjusted to 30mg or 45mg per day based on glycemic response.

• Missed Dose: If a dose is missed, take it as soon as possible. If it's close to the next scheduled dose, skip the missed dose and resume the regular schedule.

Precautions and Warnings

1. Not for Type 1 Diabetes – Piosteris 15 is ineffective in type 1 diabetes or diabetic ketoacidosis.

2. Heart Failure Risk – Use with caution in patients with a history of congestive heart failure (CHF).

3. Bladder Cancer Risk – Long-term use of Pioglitazone has been linked to an increased risk of bladder cancer.

4. Liver Function Monitoring – Liver enzyme levels should be periodically checked.

5. Bone Fracture Risk – Increased risk of fractures in postmenopausal women.

6. Pregnancy & Breastfeeding – Not recommended for pregnant or lactating women.

7. Macular Edema – Can lead to fluid accumulation in the eye, affecting vision.

Possible Side Effects of Piosteris 15

Common Side Effects:

• Weight gain

• Swelling (edema)

• Headache

• Muscle pain

• Sinus infections

Serious Side Effects:

• Heart failure symptoms (shortness of breath, swelling in legs/feet)

• Liver dysfunction (jaundice, dark urine, upper abdominal pain)

• Bladder cancer symptoms (blood in urine, painful urination)

• Hypoglycemia (especially when used with insulin or sulfonylureas)

• Bone fractures (especially in women)

If you experience severe side effects, seek immediate medical attention.

Drug Interactions

Piosteris 15 may interact with several medications, including:

• Oral contraceptives – Can reduce the effectiveness of birth control pills.

• Insulin & Sulfonylureas – Increased risk of hypoglycemia.

• Diuretics & NSAIDs – May increase fluid retention and worsen heart failure.

• Gemfibrozil – May increase pioglitazone levels, leading to a higher risk of side effects.

• Rifampin – Can decrease pioglitazone effectiveness.

Always inform your doctor about any medications you are taking to prevent adverse interactions.

Piosteris 15 Price in India

The Pioglitazone 15mg price varies depending on the brand and pharmacy. On average, it costs ₹50 – ₹150 per strip of 10 tablets. Prices may differ based on availability and location.

Storage Instructions

• Store at room temperature (15-30°C).

• Keep away from moisture, heat, and direct sunlight.

• Keep out of reach of children and pets.

Conclusion

Piosteris 15 (Pioglitazone 15mg) is a highly effective medication for managing type 2 diabetes mellitus. By improving insulin sensitivity, it helps in better glycemic control and provides additional cardiovascular and metabolic benefits. However, it must be used with caution, considering its potential side effects and risks. Always consult a healthcare provider before starting or adjusting the dosage of Piosteris 15 to ensure its safe and effective use.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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