PIOSTERIS 15

PIOSTERIS 15 is an oral antidiabetic medication containing pioglitazone 15 mg, used in the management of type 2 diabetes mellitus. It belongs to the thiazolidinedione (TZD) class of drugs and works by improving insulin sensitivity in the body. When used alongside a healthy diet and regular exercise, PIOSTERIS 15 helps regulate blood sugar levels, making it a valuable addition to diabetes care—especially for patients who are unable to achieve adequate control with metformin or sulfonylureas alone.

What is PIOSTERIS 15 (Pioglitazone 15 mg Tablet)?

PIOSTERIS 15 is a pioglitazone tablet containing pioglitazone 15 mg, a thiazolidinedione that acts by increasing the body’s sensitivity to insulin. It does not cause the pancreas to produce more insulin, but instead helps the body use its natural insulin more effectively—particularly in the muscles, liver, and fat tissues.

This medication is typically prescribed as monotherapy or in combination with other antidiabetic agents for better glycemic control.

Uses of Pioglitazone 15 mg

PIOSTERIS 15 is indicated for:

• Type 2 Diabetes Mellitus – To help control high blood sugar in adults when diet and exercise alone are not sufficient.

• Combination Therapy – Can be used with metformin, sulfonylureas, or insulin for enhanced glucose control.

• Insulin Sensitization – Especially useful in insulin-resistant individuals, such as those with metabolic syndrome.

Note: It is not suitable for type 1 diabetes or diabetic ketoacidosis.

Side Effects of Pioglitazone 15 mg

While pioglitazone tablet is generally well-tolerated, it can cause side effects in some individuals.

Common side effects:

• Weight gain

• Swelling (fluid retention)

• Muscle aches

• Upper respiratory infections

• Headache

Serious but less common side effects:

• Heart failure (especially in those with pre-existing cardiac conditions)

• Bone fractures (particularly in women)

• Bladder cancer (rare; long-term use may increase risk)

• Liver issues (monitor liver enzymes)

• Vision changes (macular edema)

If you notice signs of shortness of breath, rapid weight gain, or yellowing of the skin/eyes, seek medical attention immediately.

Precautions Before Using Pioglitazone 15 mg

Before starting PIOSTERIS 15, discuss the following with your healthcare provider:

• History of heart failure or cardiac disease

• Liver problems or elevated liver enzymes

• Bladder cancer or blood in the urine

• Pregnancy or breastfeeding

• Risk of bone fractures, especially in postmenopausal women

• Swelling or fluid retention

Routine monitoring of liver function, weight, and heart health is recommended during treatment.

Drug Interactions – What Drugs Interact with Pioglitazone 15 mg?

Several medications can interact with pioglitazone 15 mg, affecting its effectiveness or increasing side effects:

• Insulin – Co-administration may increase risk of fluid retention and heart failure.

• Oral contraceptives – Pioglitazone may reduce their effectiveness.

• Gemfibrozil – Can increase pioglitazone levels and side effects.

• Rifampicin – Can reduce pioglitazone’s effectiveness.

• Diuretics (water pills) – May increase the risk of edema.

• Corticosteroids or beta-blockers – May affect blood glucose levels.

Always inform your doctor of all medications, supplements, and herbal products you are using before starting PIOSTERIS 15.

Conclusion:

PIOSTERIS 15 (pioglitazone 15 mg tablet) offers an effective treatment option for adults with type 2 diabetes who need improved insulin sensitivity and blood sugar control. When used under proper medical guidance, it can significantly enhance metabolic control with a relatively low risk of hypoglycemia. However, due care should be taken regarding potential pioglitazone side effects, especially related to heart and liver health.