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Jul 04, 2022

Introduction

SEIZMET TRIO 0.2 is a powerful combination medication used for the management of type 2 diabetes mellitus (T2DM). It contains three active ingredients: Glimepiride (2mg), Metformin SR (500mg), and Voglibose (0.2mg), each contributing uniquely to blood sugar control. This medication is designed to improve glycemic control in patients who struggle to maintain optimal blood sugar levels through diet and exercise alone. By combining these three agents, SEIZMET TRIO 0.2 enhances insulin production, reduces glucose absorption, and improves insulin sensitivity.

Key Ingredients and Their Functions

1. Glimepiride (2mg)

Glimepiride belongs to the sulfonylurea class of medications. It works by stimulating the pancreatic beta cells to release insulin, which helps lower blood glucose levels. Key benefits of Glimepiride include:

  • Increases insulin secretion from the pancreas

  • Helps in better postprandial glucose control

  • Reduces the risk of diabetes-related complications

2. Metformin SR (500mg)

Metformin is a biguanide that plays a central role in diabetes management. The sustained-release (SR) formulation ensures gradual absorption, reducing gastrointestinal side effects. Metformin works by:

  • Decreasing hepatic glucose production (reducing sugar release from the liver)

  • Improving insulin sensitivity in muscle cells

  • Reducing intestinal absorption of glucose

  • Promoting weight loss in overweight diabetic patients

3. Voglibose (0.2mg)

Voglibose is an alpha-glucosidase inhibitor that delays carbohydrate digestion and absorption in the intestine. Key benefits of Voglibose include:

  • Reduces postprandial hyperglycemia (spikes in blood sugar after meals)

  • Delays glucose absorption, ensuring stable blood sugar levels

  • Prevents diabetes complications by maintaining controlled glucose levels

How SEIZMET TRIO 0.2 Works

The combined action of Glimepiride, Metformin, and Voglibose ensures a comprehensive approach to blood sugar regulation:

  • Glimepiride enhances insulin secretion.

  • Metformin decreases glucose production and improves insulin sensitivity.

  • Voglibose reduces post-meal glucose spikes.

This triple mechanism provides a synergistic effect, making SEIZMET TRIO 0.2 an effective therapy for patients with uncontrolled type 2 diabetes.

Uses of SEIZMET TRIO 0.2

  • Management of Type 2 Diabetes Mellitus

  • Improves insulin resistance and glycemic control

  • Prevents diabetes-related complications

  • Reduces post-meal blood sugar spikes

  • Helps in weight management for diabetic patients

Dosage and Administration

  • The recommended dose is usually once or twice daily, as prescribed by the doctor.

  • It should be taken before or with meals to maximize its effectiveness.

  • Swallow the tablet whole with water; do not crush or chew.

  • Maintain a balanced diet and regular exercise for best results.

Side Effects

While SEIZMET TRIO 0.2 is generally well-tolerated, some individuals may experience:

Common Side Effects

  • Hypoglycemia (low blood sugar) – Symptoms include dizziness, sweating, and confusion.

  • Gastrointestinal discomfort – Nausea, bloating, and diarrhea due to Metformin.

  • Flatulence and abdominal pain – Due to Voglibose’s effect on carbohydrate digestion.

Rare but Serious Side Effects

  • Severe hypoglycemia (especially if taken without food)

  • Lactic acidosis (a rare but serious complication of Metformin overdose)

  • Allergic reactions like rash, itching, or swelling

  • Liver dysfunction in rare cases

Precautions and Warnings

  • Not suitable for Type 1 diabetes or diabetic ketoacidosis.

  • Should not be used in patients with severe kidney or liver impairment.

  • Regular monitoring of blood sugar levels is required.

  • Avoid alcohol consumption as it may increase the risk of lactic acidosis.

  • Pregnant and breastfeeding women should consult a doctor before use.

Drug Interactions

  • Avoid combining with other sulfonylureas to prevent excessive insulin secretion.

  • Caution with beta-blockers, as they may mask hypoglycemia symptoms.

  • Should not be taken with alcohol or corticosteroids, which can impact blood sugar control.

  • Interactions with certain antibiotics may alter the drug’s effectiveness.

Lifestyle and Dietary Recommendations

  • Maintain a healthy, balanced diet with complex carbohydrates and fiber.

  • Regular physical activity enhances insulin sensitivity.

  • Monitor blood sugar levels frequently to adjust medication if needed.

  • Stay hydrated to prevent dehydration and maintain kidney health.

Conclusion

SEIZMET TRIO 0.2 is a highly effective medication for managing Type 2 Diabetes Mellitus. Its combination of Glimepiride, Metformin SR, and Voglibose works synergistically to regulate blood sugar levels, improve insulin sensitivity, and prevent diabetes-related complications. Regular blood sugar monitoring, a healthy diet, and an active lifestyle are crucial to maximizing the benefits of this medication. Always consult your doctor before starting or modifying any diabetes treatment.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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