Deflazacort (30mg) k ,

Feb 05, 2024

Deflazacort 

Introduction

DEFRACKET 30 is a high-potency corticosteroid formulation manufactured by Steris Healthcare Pvt Ltd, containing Deflazacort 30 mg. It is widely used for treating severe inflammatory and autoimmune conditions. With enhanced anti-inflammatory effects and a favorable safety profile compared to other corticosteroids, deflazacort has become a preferred choice among physicians.In this article, we cover all essential aspects of deflazacort, including its uses, benefits, dosage, safety profile, and why you should choose DEFRACKET 30 from Steris Healthcare.

What is Deflazacort?

Deflazacort is a synthetic corticosteroid that functions by suppressing the immune response and reducing inflammation. It is used in the management of a wide variety of chronic and acute inflammatory diseases. Compared to other steroids like prednisolone, deflazacort has a lower risk of weight gain and bone loss.

Composition of DEFRACKET 30

Each tablet of DEFRACKET 30 contains:

  • Deflazacort 30 mg

This higher strength is typically reserved for severe cases or for patients requiring a higher dose of corticosteroid therapy.

Deflazacort Uses

The primary therapeutic applications of deflazacort include:

1. Autoimmune Diseases

  • Rheumatoid arthritis

  • Psoriatic arthritis

  • Systemic lupus erythematosus (SLE)

2. Severe Allergies and Respiratory Conditions

  • Chronic asthma

  • Allergic rhinitis

  • Bronchial inflammation

3. Neuromuscular Disorders

  • Duchenne Muscular Dystrophy (DMD) – commonly used to improve strength and delay disease progression.

4. Nephrotic Syndrome

  • Reduces protein loss in urine and relieves swelling.

5. Skin Conditions

  • Eczema, dermatitis, and severe psoriasis

6. Organ Transplantation

  • Helps prevent rejection by suppressing immune function.

7. Blood Disorders and Certain Cancers

  • As part of adjunct therapy in specific hematological diseases.

Clinical Evidence and Efficacy of Deflazacort

Multiple studies show that deflazacort tablets have equivalent efficacy to traditional corticosteroids with lower risks of:

  • Weight gain

  • Bone demineralization

  • Growth suppression in children

This makes deflazacort 30 mg tablets a clinically effective option for long-term use when needed.

Deflazacort 30 mg Dosage and Administration

The exact dosage depends on the condition being treated and the patient’s clinical response.
For adults, typical starting doses range from 6 mg to 90 mg per day, with Deflazacort 30 mg being used in moderate to severe cases.

  • Route: Oral

  • Timing: Once or twice daily, preferably with food

Never self-medicate or stop corticosteroids abruptly. Dosage must be tapered down gradually under medical supervision.

Side Effects of Deflazacort

Common Side Effects:

  • Increased appetite

  • Weight gain

  • Mood changes

  • Insomnia

  • Elevated blood sugar levels

Long-Term Side Effects:

  • Osteoporosis

  • Cushingoid appearance

  • Increased susceptibility to infections

  • Growth retardation in children

All corticosteroids including deflazacort tablets must be used with caution under a physician’s guidance.

Precautions and Contraindications

  • Use cautiously in diabetic and hypertensive patients.

  • Not suitable for patients with untreated systemic infections.

  • Avoid live vaccines during deflazacort therapy.

  • Pregnant or breastfeeding women should use it only if prescribed.

Drug Interactions

Deflazacort may interact with:

  • NSAIDs (e.g., ibuprofen, aspirin)

  • Diabetic medications

  • Antihypertensives

  • Antifungals and antibiotics

  • Antiepileptics

Always inform your doctor about all current medications and supplements.

Why Choose DEFRACKET 30 from Steris Healthcare Pvt Ltd?

  • Steris Healthcare follows stringent WHO-GMP manufacturing standards.

  • DEFRACKET 30 ensures accurate potency, purity, and consistent therapeutic effect.

  • Trusted by healthcare professionals across India for quality and safety.

FAQs on Deflazacort

Q1. What is deflazacort used for?

Ans: Deflazacort is used to treat autoimmune diseases, asthma, muscular dystrophy, severe allergies, nephrotic syndrome, and various skin and inflammatory conditions.

Q2. Is deflazacort 30 mg safe for long-term use?

Ans: It is generally safe under medical supervision with regular monitoring for bone density, glucose levels, and other parameters.

Q3. Can I stop deflazacort 30 mg suddenly?

Ans: No. Stopping it abruptly can lead to adrenal insufficiency. Always taper the dose gradually under your doctor’s advice.

Q4. Can deflazacort be used in children?

Ans: Yes, especially in conditions like Duchenne Muscular Dystrophy, but the dosage must be strictly monitored by a pediatrician.

Q5. Is deflazacort a painkiller?

Ans: No. It is not a painkiller but reduces pain by controlling inflammation in chronic conditions.

Conclusion

Deflazacort, the active ingredient in DEFRACKET 30, is a powerful, well-studied corticosteroid that helps manage a wide range of chronic, inflammatory, and autoimmune diseases. With its favorable safety profile and proven clinical effectiveness, it is a preferred choice in high-dose steroid therapy when guided by healthcare professionals.Choose DEFRACKET 30 from Steris Healthcare Pvt Ltd for guaranteed quality, trusted results, and ethical pharmaceutical excellence.Steris Healthcare ensures purity, efficacy, and affordability with every tablet of deflazacort.

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