ST- GLIPTIN DAPA 100/10 is a prescription medicine containing a combination of two oral antidiabetic agents: Sitagliptin Phosphate and Dapagliflozin. This combination is used as part of a comprehensive treatment plan for adults with type 2 diabetes mellitus when improved blood glucose control is required.combined in oral medications used to manage type 2 diabetes

Sitagliptin belongs to a class of medicines known as DPP-4 inhibitors, while Dapagliflozin belongs to the class of SGLT2 inhibitors. These medicines work through different pathways to help regulate blood glucose levels.

This medication should be taken only under the guidance of a qualified healthcare professional. Treatment decisions depend on factors such as blood sugar levels, medical history, kidney function, and other ongoing therapies.

Uses of Sitagliptin Phosphate and Dapagliflozin

Healthcare professionals may prescribe this combination for:

• Management of type 2 diabetes mellitus

• Improvement of blood glucose control when combination therapy is appropriate

• Supporting diabetes management along with diet and exercise

• Patients requiring more than one oral antidiabetic medicine

This medicine is not intended for the treatment of type 1 diabetes or diabetic ketoacidosis unless specifically directed by a healthcare professional.

How Sitagliptin and Dapagliflozin Work

Sitagliptin

Sitagliptin works by inhibiting the DPP-4 enzyme, which increases the activity of incretin hormones. These hormones help regulate blood glucose by increasing insulin release when glucose levels are elevated and reducing glucose production by the liver.

Dapagliflozin

Dapagliflozin works by blocking the SGLT2 protein in the kidneys. This helps reduce glucose reabsorption and allows excess glucose to be removed through urine.

The combination provides complementary effects by addressing different mechanisms involved in blood glucose regulation.

Directions for Use

• Take the tablet exactly as prescribed by your healthcare provider.

• Swallow the tablet whole with water.

• Do not crush, chew, or alter the tablet unless advised.

• Take the medicine at the recommended time each day.

• Follow your prescribed diet and exercise plan along with medication.

Do not change the dose or stop treatment without consulting your doctor.

Possible Side Effects

Like all medicines, Sitagliptin Phosphate and Dapagliflozin may cause side effects.

Common side effects may include:

• Increased urination

• Thirst

• Nausea

• Stomach discomfort

• Headache

• Upper respiratory symptoms

• Genital or urinary tract infections

• Low blood sugar, especially when combined with other diabetes medicines

Contact a healthcare professional if you experience:

• Signs of dehydration

• Severe abdominal pain

• Symptoms of allergic reaction

• Unusual weakness or confusion

• Symptoms of diabetic ketoacidosis

Precautions and Warnings

Before using this medicine, inform your healthcare provider if you have:

• Kidney disease

• Liver problems

• History of urinary infections

• Pancreatic problems

• Heart-related conditions

• Low blood pressure

• Pregnancy or breastfeeding plans

Your doctor may recommend regular monitoring of:

• Blood glucose levels

• Kidney function

• Overall diabetes control

Drug Interactions

Inform your doctor about all medicines, supplements, and herbal products you are taking.

Medicines that may require special consideration include:

• Other diabetes medicines

• Insulin therapy

• Diuretics (water tablets)

• Certain medicines affecting kidney function

• Corticosteroids

• Medicines affecting blood sugar levels

Your healthcare provider will determine the appropriate treatment approach.

Storage Instructions

• Store below 25°C.

• Keep tablets protected from moisture and direct sunlight.

• Store in the original packaging.

• Keep away from children.

• Do not use after the expiry date.

Frequently Asked Questions 

1. What is Sitagliptin Phosphate and Dapagliflozin used for?

Sitagliptin Phosphate and Dapagliflozin is prescribed for adults with type 2 diabetes to help improve blood glucose control along with diet and exercise.

2. What are the ingredients in Sitagliptin Phosphate and Dapagliflozin?

Each tablet contains Sitagliptin Phosphate equivalent to Sitagliptin 100 mg and Dapagliflozin 10 mg.

3. How does this combination medicine work?

Sitagliptin improves insulin regulation through incretin hormones, while Dapagliflozin helps remove excess glucose through urine.

4. Is this medicine for type 1 diabetes?

No. This combination is generally used for type 2 diabetes management.

5. Is a prescription required for Sitagliptin and Dapagliflozin?

Yes. It is a prescription-only medicine and should be used under medical supervision.

6. Can I stop taking this medicine if my sugar levels improve?

Do not stop treatment without consulting your healthcare provider. Diabetes management usually requires ongoing monitoring.

7. Does Dapagliflozin increase urination?

Yes. Increased urination may occur because Dapagliflozin works by helping remove glucose through urine.

8. Can this medicine cause low blood sugar?

Low blood sugar may occur, particularly when used with insulin or other medicines that increase insulin levels.

9. Should kidney function be checked during treatment?

Yes. Kidney function assessment may be recommended before and during treatment depending on individual health conditions.

10. Can this medicine replace diet and exercise?

No. A balanced diet, physical activity, and regular monitoring remain important parts of diabetes management.

11. Who should avoid this medicine?

People with certain kidney conditions, allergies to ingredients, or specific medical concerns should consult their healthcare provider before use.

12. How should Sitagliptin Phosphate and Dapagliflozin tablets be stored?

Store below 25°C in a dry place away from moisture, heat, and direct sunlight.

Product Specifications