Sitagliptin Phosphate and Dapagliflozin "'''

Aug 25, 2023

Introduction: Sitagliptin Phosphate and Dapagliflozin Combination

ST-GLIPTIN DAPA 100/10 is an advanced oral antidiabetic medication combining Sitagliptin Phosphate 100 mg and Dapagliflozin 10 mg. This fixed-dose combination offers dual-action glucose control for adults with type 2 diabetes mellitus who require better glycemic control along with diet and exercise.

Sitagliptin phosphate tablets belong to the DPP-4 inhibitor class, while Dapagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor. Together, they work synergistically to improve fasting and post-meal blood sugar levels, promote weight loss, and support cardiovascular health.

What is Sitagliptin Phosphate?

Sitagliptin phosphate is a DPP-4 inhibitor that increases the levels of incretin hormones (GLP-1 and GIP), which help regulate insulin secretion and reduce glucagon release.

Sitagliptin Phosphate Tablets Uses:

  • Controls blood sugar levels in type 2 diabetes

  • Enhances insulin release post-meal

  • Reduces hepatic glucose production

What is Dapagliflozin 10 mg?

Dapagliflozin 10 mg is an SGLT2 inhibitor that works in the kidneys by preventing glucose reabsorption. This results in increased urinary glucose excretion, improved glycemic control, and modest weight loss.

Dapagliflozin 10 mg Uses:

  • Type 2 diabetes mellitus

  • Cardiovascular risk reduction in diabetics

  • May support kidney protection (under specialist advice)

Composition of ST-GLIPTIN DAPA 100/10

  • Sitagliptin Phosphate: 100 mg

  • Dapagliflozin: 10 mg

  • Form: Oral tablet

  • Brand: ST-GLIPTIN DAPA 100/10

  • Manufacturer: Steris Healthcare

How ST-GLIPTIN DAPA 100/10 Works

The combination delivers dual action:

  • Sitagliptin phosphate enhances the body's natural ability to control blood sugar through incretin hormones.

  • Dapagliflozin reduces blood glucose by eliminating it through urine and lowering renal glucose threshold.

Together, they:

  • Improve HbA1c levels

  • Control fasting and postprandial blood glucose

  • Promote weight loss

  • Offer cardiovascular and renal benefits

Dosage and Administration

  • Recommended Dose: One tablet of ST-GLIPTIN DAPA 100/10 daily, usually in the morning

  • With or without food

  • Adjustments may be needed in patients with renal impairment

  • Always follow your physician’s advice

Benefits of ST-GLIPTIN DAPA 100/10

  • Dual mechanism for effective blood sugar control

  • Helps reduce body weight and blood pressure

  • Suitable for patients uncontrolled on monotherapy

  • Reduces risk of diabetes-related cardiovascular complications

  • Convenient once-daily dose

Possible Side Effects

Sitagliptin phosphate tablets side effects:

  • Headache

  • Nasopharyngitis

  • Hypoglycemia (rare when used alone)

Dapagliflozin 10 mg side effects:

  • Increased urination

  • Urinary tract infections (UTIs)

  • Genital fungal infections

  • Dehydration

  • Low blood pressure

Seek medical help if you experience severe symptoms or allergic reactions.

Precautions and Warnings

  • Not for use in type 1 diabetes or diabetic ketoacidosis

  • Monitor kidney function before and during treatment

  • Avoid in patients with severe renal impairment

  • Use with caution in elderly or those on diuretics

  • Inform your doctor if you are pregnant, breastfeeding, or planning surgery

Why Steris Healthcare is Better Than Others

ST-GLIPTIN DAPA 100/10 is brought to you by Steris Healthcare, a name synonymous with excellence in evidence-based, affordable pharmaceuticals.

Why choose Steris:

  • ✅ WHO-GMP certified manufacturing

  • ✅ Scientifically backed and clinically tested formulations

  • ✅ Accurate dosing for optimal results

  • ✅ Trusted by endocrinologists and diabetologists

  • ✅ Easy access via SterisOnline.in

Steris ensures purity, potency, affordability, and therapeutic effectiveness with every product.

FAQs – Sitagliptin Phosphate and Dapagliflozin Tablets

1. What is ST-GLIPTIN DAPA 100/10 used for?
It is used for managing type 2 diabetes by combining the benefits of Sitagliptin and Dapagliflozin.

2. What is the benefit of combining Sitagliptin with Dapagliflozin?
It provides dual action on blood glucose regulation – one by increasing insulin secretion and the other by promoting urinary glucose excretion.

3. Can this tablet cause weight loss?
Yes, Dapagliflozin promotes modest weight loss in many patients.

4. Are there any risks of low blood sugar?
The risk is low when used alone, but may increase if combined with sulfonylureas or insulin.

5. Can I stop taking the tablet once my sugar is normal?
No. Diabetes is a chronic condition. Always follow your doctor’s instructions for medication adjustments.

Conclusion

ST-GLIPTIN DAPA 100/10 is an advanced oral combination therapy of Sitagliptin phosphate 100 mg and Dapagliflozin 10 mg, designed to provide enhanced glycemic control in adults with type 2 diabetes. Trusted by physicians and manufactured by Steris Healthcare, this dual-action tablet helps reduce blood sugar, supports weight management, and improves long-term health outcomes.

Choose ST-GLIPTIN DAPA 100/10 to manage diabetes smarter—with innovation, reliability, and proven science.

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