Sitagliptin (50mg), Metformin Hydrochloride (1000mg) & Glimepiride (2mg) - Benefits, Dosage, Side Effects.

Introduction to ST GLIPTIN GM 2/1000

ST GLIPTIN GM 2/1000 is a highly effective triple combination therapy designed to provide comprehensive blood sugar control in patients with type 2 diabetes mellitus. It combines the strengths of Sitagliptin, a DPP-4 inhibitor; Metformin, a first-line biguanide; and Glimepiride, a sulfonylurea, offering multi-targeted action to control blood glucose levels while minimizing complications associated with diabetes.

Uses of ST GLIPTIN GM 2/1000

This triple drug combination is indicated for:

• Management of Type 2 Diabetes Mellitus when diet, exercise, and monotherapy do not provide adequate glycemic control

• As part of combination therapy to reduce HbA1c levels

• Prevention of long-term complications like nephropathy, neuropathy, and retinopathy associated with poorly controlled diabetes

How ST GLIPTIN GM 2/1000 Works

• Sitagliptin enhances the body’s natural ability to regulate blood sugar by inhibiting DPP-4, which increases levels of incretin hormones, leading to more insulin release and less glucagon secretion.

• Metformin decreases hepatic glucose production and improves insulin sensitivity.

• Glimepiride stimulates the pancreas to release more insulin, helping lower blood sugar levels effectively.

This multi-mechanism approach ensures better fasting and postprandial blood glucose control.

Dosage and Administration

• Recommended Dose: One tablet once daily, preferably with the first main meal to reduce gastrointestinal side effects.

• Adjustment: Dosage should be adjusted based on patient’s blood glucose response and doctor's evaluation.

Important: Always follow the physician’s prescription to avoid hypoglycemia.

Benefits of ST GLIPTIN GM 2/1000

• Triple mechanism targets multiple pathways of diabetes
• Helps achieve better control over fasting and post-meal sugar spikes
• Reduces the need for insulin injections in many cases
• Supports long-term glycemic control and complication prevention
• Convenient once-daily dosing improves compliance

Possible Side Effects

Common side effects may include:

• Nausea, diarrhea, or stomach upset (due to Metformin)

• Hypoglycemia (low blood sugar, mainly due to Glimepiride)

• Headache

• Mild skin rash

• Dizziness

Serious but rare effects:

• Lactic acidosis (rare with Metformin)

• Severe hypoglycemia if combined with other anti-diabetic agents

• Pancreatitis (rare with Sitagliptin)

Precautions and Warnings

• Regularly monitor blood glucose levels.

• Caution in patients with kidney, liver, or cardiac impairment.

• Not recommended during pregnancy or breastfeeding unless advised by a healthcare professional.

• Avoid excessive alcohol intake to reduce the risk of lactic acidosis.

Storage Instructions

• Store at a temperature below 25°C.

• Keep away from direct light, heat, and moisture.

• Keep out of reach of children.

Why Choose ST GLIPTIN GM 2/1000 by Steris Healthcare?

Steris Healthcare offers premium-quality diabetic management solutions like ST GLIPTIN GM 2/1000, manufactured under WHO-GMP certified facilities. This combination ensures efficacy, safety, and patient-centric outcomes, making it a trusted choice for physicians and diabetologists across India.

Frequently Asked Questions (FAQs)

Q1. Can ST GLIPTIN GM 2/1000 be used alone for diabetes?
A1. It is usually prescribed when single or dual therapy is insufficient to control blood sugar.

Q2. Should I worry about hypoglycemia with this combination?
A2. Hypoglycemia risk exists due to Glimepiride; regular monitoring and proper meal intake are important.

Q3. Can this be used in elderly patients?
A3. Yes, but with careful dose adjustment and monitoring due to higher risk of kidney function decline.

Conclusion

ST GLIPTIN GM 2/1000 offers a powerful, synergistic triple-action formula to effectively manage type 2 diabetes and achieve better glycemic control. Backed by Steris Healthcare’s trusted manufacturing quality, it delivers not just numbers control but also helps protect long-term health, ensuring a better quality of life for diabetic patients.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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