Roflumilast 500 mcg Tablet – Uses, Dosage, Side Effects & Mechanism of Action

If you’re struggling with Chronic Obstructive Pulmonary Disease (COPD), particularly chronic bronchitis with frequent flare-ups, your doctor may prescribe roflumilast 500 mcg as part of your long-term treatment plan.

Marketed under the trusted brand FLUROMILAST 500 by Steris Healthcare, this once-daily tablet offers advanced protection against inflammation in the lungs — helping you breathe easier, reduce symptoms, and avoid frequent hospital visits.

In this blog, we’ll break down how roflumilast 500 mcg works, its benefits, how to take it, safety tips, and why patients trust FLUROMILAST 500 for managing chronic respiratory conditions.

What is Roflumilast 500 mcg?

Roflumilast is a prescription medication used to prevent exacerbations (flare-ups) in patients with severe COPD associated with chronic bronchitis.

It is not a bronchodilator, so it won’t relieve sudden breathing trouble, but it helps control inflammation in the lungs over time. This makes it an ideal maintenance therapy in addition to inhalers and other medications.

FLUROMILAST 500 contains high-purity roflumilast 500 mcg and is formulated for once-daily oral use, making it easy to incorporate into your routine.

How Roflumilast Works – Mechanism of Action

Understanding the roflumilast mechanism of action is key to appreciating how it helps your lungs.

Roflumilast is a selective phosphodiesterase-4 (PDE4) inhibitor. It works by:

• Reducing inflammation in the lungs at a cellular level

• Suppressing cytokines and immune cell activity involved in chronic lung inflammation

• Lowering mucus production

• Decreasing the frequency and severity of COPD exacerbations

By targeting the inflammatory process, roflumilast 500 mcg helps to preserve lung function and reduce hospitalizations due to breathing complications.

Roflumilast 500 mcg Uses

The primary uses of roflumilast 500 mcg include:

• Long-term treatment of severe COPD, especially in patients with chronic bronchitis and a history of frequent exacerbations

• Reduction of inflammation in the airways

• Preventing disease progression in combination with bronchodilators

It is not a rescue medication for sudden breathing problems but is essential for daily management of inflammation in COPD.

Roflumilast Dose

The standard adult roflumilast dose is:

• 500 mcg once daily, with or without food

Some doctors may begin with a 250 mcg dose for the first few weeks to minimize side effects and then increase to 500 mcg daily.

Always follow your doctor’s specific dosing instructions.

How to Take Roflumilast 500 mcg

Taking FLUROMILAST 500 is simple:

1. Take one tablet daily, at the same time each day

2. Can be taken with or without food

3. Swallow whole with a glass of water – do not crush or chew

4. Do not skip doses, as consistency is key to effectiveness

5. Store in a cool, dry place, away from moisture and heat

If you miss a dose, take it as soon as you remember. Skip it if it’s almost time for the next dose—do not double up.

Roflumilast Side Effects

Like all medications, roflumilast 500 mcg may cause side effects in some patients. Common ones include:

• Nausea

• Weight loss

• Diarrhea

• Headache

• Loss of appetite

Less commonly, some may experience mood changes like anxiety or depression. Report any serious or persistent side effects to your doctor immediately.

Your doctor may monitor your weight and mental health regularly while you're on roflumilast.

Precautions to Take

• Inform your doctor if you have liver disease or a history of depression.

• Avoid stopping the medicine suddenly without medical advice.

• Maintain a healthy diet to balance potential weight loss.

• Take the medicine at the same time daily for best results.

Why Choose Steris Healthcare?

When it comes to respiratory health, patients need medicines they can trust. Steris Healthcare is committed to providing high-quality, affordable, and reliable treatments like FLUROMILAST 500 (Roflumilast 500 mcg).

• Manufactured under WHO-GMP certified standards

• Ensures consistent quality and safety

• Wide availability across India

• Trusted by doctors and patients alike

Choosing Steris Healthcare means choosing safety, effectiveness, and affordability.

Frequently Asked Questions

1. What is roflumilast 500 mcg used for?
It is used to prevent flare-ups in severe COPD with chronic bronchitis.

2. How to take roflumilast 500 mcg?
Take one tablet daily, with or without food, as prescribed by your doctor.

3. Is roflumilast safe for long-term use?
Yes, it is safe when taken under medical supervision for long-term COPD management.

4. Can roflumilast be used for asthma?
It is primarily approved for COPD, not asthma, unless prescribed by a doctor.

5. Does roflumilast cause weight loss?
Yes, some patients may experience weight loss. Monitoring diet and weight is important.

Conclusion

Roflumilast 500 mcg is a highly effective preventive medicine for patients with severe COPD and chronic bronchitis. By reducing inflammation, preventing flare-ups, and improving long-term lung health, it plays a vital role in managing chronic respiratory conditions.

If you are a COPD patient looking for a reliable solution, consult your doctor about FLUROMILAST 500 by Steris Healthcare – a trusted name in advanced respiratory care.

Take a step towards better breathing – Ask your doctor today about FLUROMILAST 500 (Roflumilast 500 mcg) from Steris Healthcare.