Mirabegron 25 mg .. . .. .

Introduction

MIRAGRON ER 25 is a premium extended-release tablet formulation of Mirabegron 25 mg, a modern therapeutic agent used to treat Overactive Bladder (OAB) symptoms. Manufactured by Steris Healthcare Pvt. Ltd., this advanced formulation helps manage urinary urgency, frequency, and urge incontinence with improved patient compliance.

Composition

• Active Ingredient: Mirabegron (25 mg)

• Form: Extended-Release Tablet

• Brand Name: MIRAGRON ER 25

• Manufacturer: Steris Healthcare Pvt. Ltd.

What is Mirabegron 25 mg Used For?

Mirabegron 25 mg is primarily used to treat:

• Overactive Bladder (OAB) symptoms, such as:

  • Urinary urgency

  • Increased urinary frequency

  • Urge urinary incontinence

• Neurogenic detrusor overactivity (off-label)

• Combination therapy with antimuscarinics for refractory OAB

How Mirabegron Works (Mechanism of Action)

Mirabegron is a β3-adrenergic receptor agonist that:

1. Relaxes the detrusor smooth muscle of the bladder during the storage phase.

2. Increases bladder capacity without impeding voiding function.

Unlike anticholinergic drugs, Mirabegron does not cause dry mouth or constipation, offering a better safety profile, especially in elderly patients.

Dosage of Mirabegron 25 mg

MIRAGRON ER 25 should be swallowed whole with water, not crushed or chewed. Take with or without food.

Mirabegron 25 mg Side Effects

Common Side Effects:

• Increased blood pressure

• Nasopharyngitis

• Urinary tract infection

• Headache

Less Common But Serious Effects:

• Palpitations

• Tachycardia

• Bladder outlet obstruction in men

• Hypersensitivity reactions (rash, angioedema)

Regular monitoring of blood pressure is recommended, especially in patients with pre-existing hypertension.

Precautions & Warnings

• Use caution in patients with severe renal or hepatic impairment.

• Not advised for patients under 18 years.

• Monitor closely in men with BPH or those on antihypertensive therapy.

• Avoid crushing or splitting the extended-release tablet.

Drug Interactions

Avoid or monitor when used with:

• Digoxin (monitor levels)

• Anticholinergics (may enhance urinary retention)

• CYP2D6 substrates (may increase plasma levels)

Why Choose MIRAGRON ER 25 by Steris Healthcare?

MIRAGRON ER 25 from Steris Healthcare is crafted to provide once-daily relief from OAB symptoms with consistent drug release, clinical-grade purity, and fewer side effects than traditional antimuscarinics.