IT PRIDE OD 150 & Itopride Hydrochloride 150mg : Uses, Dosage, Side Effects,Composition , ETC......

May 07, 2024

Introduction

IT PRIDE OD 150 is a once-daily prokinetic agent that contains Itopride Hydrochloride 150 mg, a potent medication used to treat gastrointestinal motility disorders. It is primarily prescribed for conditions like functional dyspepsia, gastric reflux, bloating, nausea, and non-ulcer dyspepsia.The OD (once-daily) formulation ensures sustained action over 24 hours, improving patient compliance while delivering consistent therapeutic benefits.

Pharmacological Profile of Itopride Hydrochloride

  • Drug Class: Prokinetic Agent

  • Molecular Formula: C20H26N4O3

  • Bioavailability: ~60%

  • Half-Life: 6 hours (sustained in OD formulation)

  • Excretion: Primarily renal (urine)

Mechanism of Action

Itopride Hydrochloride works through dual action:

  1. D2 Dopamine Receptor Antagonism

    • Inhibits dopamine, which otherwise slows GI motility.

    • Helps reduce nausea and promotes movement of food through the stomach.

  2. Acetylcholinesterase Inhibition

    • Increases levels of acetylcholine in the enteric nervous system.

    • Boosts gastric contractions and enhances peristalsis.

This makes Itopride Hydrochloride Tablets effective in accelerating gastric emptying, particularly helpful for patients with gastroparesis and chronic dyspepsia.

Clinical Indications

Itopride Hydrochloride 150 mg Uses:

  • Gastroparesis (Delayed gastric emptying)

  • Functional Dyspepsia

  • Chronic Gastritis

  • GERD-associated dysmotility

  • Early Satiety and Bloating

  • Post-surgical digestive dysfunction

Benefits of IT PRIDE OD 150

  • Promotes natural gastric emptying

  • Prevents reflux and bloating

  • Reduces nausea and vomiting

  • Enhances appetite and digestion

  • Minimizes epigastric discomfort

  • No significant interaction with the central nervous system (non-sedative)

  • Does not affect prolactin levels (unlike other prokinetics)

Dosage and Administration

  • Standard Dosage: One tablet daily, preferably before breakfast

  • Duration: As prescribed (usually 2–4 weeks depending on the condition)

  • Route: Oral

Do not chew or break the tablet; swallow it whole for optimal extended release.

Safety and Side Effects

Itopride Hydrochloride Tablets are generally well tolerated. However, some mild and temporary side effects may include:

Contraindications:

  • Known hypersensitivity to Itopride Hydrochloride

  • GI hemorrhage or mechanical obstruction

  • History of intestinal perforation

Precautions:

  • Pregnancy & lactation – Use only if advised by a doctor

  • Avoid in children unless specifically recommended

  • Caution in renal impairment

Frequently Asked Questions (FAQ)

Q1. What is Itopride Hydrochloride 150 mg used for?

Used to enhance gastric motility, treat chronic indigestion, gastroparesis, and post-operative gastric dysfunction.

Q2. Is Itopride Hydrochloride safe for long-term use?

Yes, under medical guidance, Itopride 150 mg is considered safe with minimal side effects even in prolonged usage.

Q3. Can IT PRIDE OD 150 be taken alongside PPIs?

Yes, it can be co-administered with proton pump inhibitors (PPIs) like omeprazole for combined action in dyspepsia and reflux.

Q4. Does it interact with other drugs?

It has low potential for drug interactions, but always consult your physician before combining with other GI medications or CNS drugs.

Q5. How soon can one feel the relief?

Most patients start noticing improvement in gastric symptoms within 3 to 5 days of starting Itopride Hydrochloride Tablets.

Conclusion

IT PRIDE OD 150, with its potent Itopride Hydrochloride 150 mg composition, offers fast, safe, and consistent relief from various gastrointestinal motility disorders. Whether it's bloating, nausea, slow digestion, or functional dyspepsia, this once-daily tablet can significantly improve your digestive health and overall well-being.Itopride Hydrochloride Tablets are trusted by gastroenterologists for their efficacy, safety, and tolerability, making them a staple in the treatment of modern gastric dysfunctions.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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