Everything You Need to Know About Calcium (500 mg) & Vitamin D3 (250 IU)
Oct 04, 2025
Calcium and Vitamin D3 are among the most important nutrients for maintaining strong bones and overall health. Whether you're concerned about osteoporosis, bone density, or general wellness, this supplement combo is often recommended by doctors and nutritionists alike.
What Is Calcium 500 mg & Vitamin D3 250 IU?
This supplement combines 500 mg of elemental calcium and 250 IU (International Units) of Vitamin D3 (also called cholecalciferol). These two nutrients work together to support bone health and calcium absorption in the body.
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Calcium (500 mg): Essential for strong bones, teeth, muscle function, and nerve transmission.
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Vitamin D3 (250 IU): Helps your body absorb calcium from your diet and maintain adequate blood levels of calcium and phosphorus.
Why Take Calcium with Vitamin D3 Together?
Vitamin D3 increases calcium absorption in your intestines. Without enough Vitamin D, your body can’t absorb enough calcium, even if you're getting it from food or supplements.
Taking both together ensures:
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Better bone mineralization
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Improved calcium absorption
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Prevention of rickets (in children) and osteomalacia or osteoporosis (in adults)
Is 500 mg of Calcium Enough?
The Recommended Dietary Allowance (RDA) for calcium depends on age and gender:
Age Group |
Recommended Calcium (per day) |
19–50 years |
1000 mg |
51–70 years (men) |
1000 mg |
51–70 years (women) |
1200 mg |
71+ years |
1200 mg |
So, 500 mg is a supplemental dose. You’ll still need to get additional calcium from your diet (milk, yogurt, cheese, leafy greens, almonds, etc.).
Is 250 IU of Vitamin D3 Enough?
Most health experts consider 250 IU of Vitamin D3 on the lower end of supplementation. The RDA for Vitamin D varies:
Age Group |
RDA (Vitamin D3) |
1–70 years |
600 IU |
71+ years |
800 IU |
Pregnant/Lactating |
600 IU |
So, 250 IU might not be sufficient on its own for many people, especially those with low sun exposure, darker skin, or older age.
How and When Should You Take Calcium + Vitamin D3?
Timing & Instructions:
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Take with food to enhance calcium absorption.
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If you're taking other medications (like thyroid meds or iron), space them out by 2–4 hours.
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You can split the dose if you're taking more than 500 mg calcium/day (body absorbs best in smaller amounts).
Are There Any Side Effects?
Like any supplement, calcium + D3 can have side effects, especially when taken in excess.
Possible Side Effects:
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Bloating or gas
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Nausea
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Kidney stones (if too much calcium over time)
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Hypercalcemia (excess calcium in blood)
Always consult your doctor, especially if you have:
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Kidney disease
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Heart conditions
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High calcium levels already
Who Should Take This Supplement?
Postmenopausal women
Elderly individuals
Vegans or lactose-intolerant individuals
People with Vitamin D deficiency
Individuals at risk of osteoporosis
But again, get a blood test and doctor’s advice before starting any supplement.
Who Should NOT Take Calcium + Vitamin D3?
Avoid or use with caution if you have:
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High calcium levels (hypercalcemia)
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Kidney stones
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Severe kidney disease
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Sarcoidosis or other conditions that increase Vitamin D levels naturally
Can You Get Calcium and Vitamin D3 from Food?
High in Calcium:
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Dairy (milk, cheese, yogurt)
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Leafy greens (kale, bok choy)
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Almonds
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Tofu (calcium-set)
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Sardines (with bones)
High in Vitamin D3:
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Fatty fish (salmon, mackerel, tuna)
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Egg yolks
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Fortified foods (milk, cereals, orange juice)
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Sunlight (your body makes Vitamin D through skin exposure)
Can You Overdose on Calcium or Vitamin D?
Yes. Too much of either can be harmful.
Upper Limits (Tolerable Intake):
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Calcium: 2,500 mg/day (19–50 years); 2,000 mg/day (51+)
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Vitamin D: 4,000 IU/day (for most adults)
Exceeding this regularly can lead to:
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Kidney stones
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Nausea
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Bone pain
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Calcium buildup in arteries
Does Calcium Interact With Other Nutrients or Medications?
Medications:
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Iron supplements (absorption interference)
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Thyroid medication (levothyroxine)
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Antibiotics (tetracyclines, quinolones)
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Blood pressure medications
Nutrients:
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Calcium competes with magnesium and iron for absorption.
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High sodium intake increases calcium excretion.
Tip: Space out your supplements for best results.
What to Look for When Buying Calcium + D3 Supplements?
Check for "elemental calcium" amount (some labels show total compound weight)
Choose D3 (cholecalciferol) — better absorbed than D2
Look for GMP-certified brands or third-party tested (like NSF or USP)
Avoid unnecessary fillers or artificial colors
If you have trouble swallowing pills, look for chewables or gummies
FAQ Section
1. Can I take Calcium + D3 at night?
Yes, as long as it's with food. Some people prefer it at night to avoid stomach issues.
2. Is 250 IU of Vitamin D enough for adults?
Usually not. 600–800 IU is recommended, so additional D3 might be needed.
3. Can I take this every day?
Yes, if you're within the recommended limits. Long-term use is generally safe if guided by a healthcare provider.
4. Does this help with hair and nails?
Indirectly. Calcium is essential for nail health, and Vitamin D supports overall cell growth, but it’s not a hair loss treatment.
Conclusion
Taking Calcium (500 mg) & Vitamin D3 (250 IU) is a smart way to support your bone health — especially if you're at risk of deficiency or don’t get enough through diet and sunlight. Just remember: balance is key, and more isn’t always better.
Always consult a healthcare provider before starting supplements, especially if you have underlying health conditions or take medications.
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