(100mg) Danazol

Introduction

DANOZOLIS 100 is a hormonal medication containing Danazol 100 mg, widely used in the treatment of conditions like endometriosis, fibrocystic breast disease, and certain types of hereditary angioedema. Danazol is a synthetic androgen derivative that works by altering hormone levels, thereby reducing symptoms associated with hormonal imbalances.

Composition of DANOZOLIS 100

• Active Ingredient: Danazol 100 mg

• Form: Capsule

• Brand Name: DANOZOLIS 100

• Therapeutic Class: Synthetic androgen / Gonadotropin inhibitor

Danazol 100 mg Uses

1. Endometriosis

• Danazol suppresses the pituitary-ovarian axis, reducing estrogen production and shrinking endometrial tissue growth outside the uterus.

2. Fibrocystic Breast Disease

• Used to treat painful or tender breast cysts by lowering estrogen levels and reducing breast nodules.

3. Hereditary Angioedema (HAE)

• Helps in preventing attacks of swelling (angioedema) in people with inherited C1-esterase inhibitor deficiency.

4. Menorrhagia & Uterine Bleeding Disorders (off-label)

• May be prescribed in cases of heavy menstrual bleeding not responding to standard therapies.

How Danazol Works (Mechanism of Action)

Danazol works by suppressing the release of gonadotropins (LH and FSH) from the pituitary gland, leading to:

• Decreased production of estrogen and progesterone in women.

• Induction of a pseudomenopausal state, helping reduce endometrial tissue growth.

• Increasing levels of C1 esterase inhibitor, preventing swelling attacks in hereditary angioedema.

It also has mild androgenic, anabolic, and anti-gonadotropic effects.

Dosage of Danazol 100 mg (DANOZOLIS 100)

Dosage should be personalized and titrated to the lowest effective dose under medical supervision.

How to Take DANOZOLIS 100

• Swallow the capsule whole with water.

• Can be taken with or without food.

• Take at the same times each day for consistent hormonal levels.

• Follow your doctor’s prescribed treatment duration—usually 3 to 6 months.

Side Effects of Danazol 100 mg

Common Side Effects

• Weight gain

• Acne

• Oily skin

• Hot flashes

• Mood swings

• Breast reduction

• Menstrual irregularities

Less Common Side Effects

• Voice deepening (may be irreversible)

• Hirsutism (excessive hair growth)

• Muscle cramps

• Vaginal dryness

Rare but Serious Side Effects

• Liver toxicity

• Intracranial hypertension

• Thromboembolism

• Elevated liver enzymes

Precautions & Warnings

• Pregnancy: Contraindicated—can harm the fetus.

• Breastfeeding: Not recommended.

• Liver disease: Avoid use in hepatic impairment.

• Kidney or heart disease: Use with caution.

• Androgenic effects: Monitor for signs of virilization.

Monitoring Required: Liver function tests, lipid profile, and hormone levels during long-term use.

Drug Interactions

Danazol may interact with:

• Warfarin (increases bleeding risk)

• Carbamazepine and Phenytoin (enhanced toxicity)

• Insulin or oral antidiabetics (alters blood glucose levels)

• Statins (risk of myopathy)

Always inform your doctor about all ongoing medications.

FAQs About Danazol 100 mg Capsule (DANOZOLIS 100)

Q1. What is Danazol used for?

Danazol is used to treat endometriosis, fibrocystic breast disease, and hereditary angioedema by regulating hormonal imbalances.

Q2. Can Danazol cure endometriosis?

Danazol can significantly reduce symptoms and shrink endometrial tissue, but recurrence may occur after stopping treatment.

Q3. Is Danazol a steroid?

Yes, Danazol is a synthetic androgen, a type of steroid hormone with mild male hormone properties.

Q4. Can men take Danazol?

Yes, in certain cases like hereditary angioedema or gynecomastia, men may be prescribed Danazol under supervision.

Q5. What precautions should women take during Danazol therapy?

Women should use non-hormonal contraception during treatment and avoid pregnancy, as Danazol can harm the unborn baby.

Conclusion

DANOZOLIS 100, containing Danazol 100 mg, is a powerful hormonal therapy used in treating reproductive and genetic disorders related to hormonal imbalance. It effectively suppresses estrogen production and prevents angioedema attacks, offering relief in tough-to-treat conditions like endometriosis and fibrocystic breast disease.Due to its androgenic effects and potential side effects, it should always be used under strict medical supervision with regular follow-ups.

About The Company

Steris Healthcare Pvt Ltd, widely recognized as Sterispharma, was established in February 2018 by a team of seasoned experts from the pharmaceutical sector. Based in Navi Mumbai, the company is proudly certified by WHO, GMP, and ISO, underscoring its unwavering commitment to quality and patient safety. Sterispharma is driven by a mission to make affordable, premium-quality medicines accessible throughout India, adhering strictly to WHO-recommended standards. Through its user-friendly online pharmacy platforms, customers can effortlessly order medications with home delivery services.

Sterispharma boasts an extensive portfolio of healthcare solutions, ranging from treatments for rare diseases to essential everyday healthcare needs. Their comprehensive product lineup addresses multiple therapeutic areas including Cardiology, Asthma, Respiratory Disorders, Nasal Care, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infective/Antibiotic Therapy, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology. Medications are easily available for online purchase through their official websites — Sterisonline, Sterisindia, and Sterispharma — offering a seamless and reliable healthcare experience.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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