VILDIABATE M 1000

VILDIABATE M 1000 is a fixed-dose combination antidiabetic tablet for adults with type 2 diabetes, used along with diet and exercise.

• Vildagliptin is a DPP-4 (dipeptidyl peptidase-4) inhibitor. It slows the breakdown of incretin hormones. This helps the pancreas release insulin when blood sugar rises after meals and reduces the glucagon that tells the liver to release glucose. Because it works mainly when glucose is high, it carries a low risk of hypoglycaemia on its own.
• Metformin hydrochloride (1000mg) is a biguanide. It lowers the glucose your liver produces and helps your body respond better to its own insulin.

Because the two work through different pathways, together they can improve blood sugar control more than either alone for many patients.

Product Information 

Detail	Information
Brand Name	VILDIABATE M 1000
Composition	Vildagliptin (assumed 50mg) + Metformin Hydrochloride 1000mg (confirm on pack)
Salt Class	DPP-4 inhibitor + Biguanide
Dosage Form	Tablet
Pack Size	Strip of 15 tablets
Manufacturer / Marketer	Steris Healthcare Pvt. Ltd.
Therapeutic Use	Type 2 diabetes mellitus in adults
Prescription Status	Prescription required (Schedule H)
Storage	Store in a cool, dry place below 30°C, away from light and moisture. Follow the pack label.
Availability	India

Why Is the Vildagliptin and Metformin Combination Important?

Over the years, high blood sugar can damage the heart, kidneys, eyes, nerves and feet. Keeping HbA1c within the target your doctor sets is one of the best ways to lower that risk. This combination matters for several reasons:

1. It targets different problems. Metformin addresses insulin resistance and liver glucose output. Vildagliptin supports the body’s own insulin response after meals and helps control glucagon.
2. It reduces pill burden. One tablet in place of two makes regular dosing easier, and consistency strongly affects long-term control.
3. Metformin is a foundation drug. It has decades of use and remains a first-line choice in type 2 diabetes care worldwide.
4. Vildagliptin is well established in India. It has been used in Indian practice for many years, and doctors are familiar with how to use it.
5. It suits people who want low hypoglycaemia risk. Neither ingredient typically causes dangerously low sugar when used alone. This matters for older adults and for people who skip meals.
6. The 1000mg strength supports higher metformin dosing. It is usually chosen once a doctor has confirmed you tolerate metformin and have adequate kidney function. The right strength is always your doctor’s decision.

Key Benefits 

1. Better Blood Sugar Control: The dual mechanism helps lower fasting glucose, after-meal glucose and HbA1c when used with a healthy lifestyle.

2. Low Risk of Hypoglycaemia on Its Own: Vildagliptin acts mainly when glucose is high, and metformin does not usually push sugar too low. The risk rises if combined with insulin or sulfonylureas, so your doctor may adjust those doses.

3. Generally Weight-Neutral: DPP-4 inhibitors usually do not cause weight gain, and metformin is often weight-neutral or may help slightly. Results vary.

4. Convenient Fixed-Dose Tablet: One tablet instead of two simplifies the routine and may help you stay consistent.

5. Long Clinical Track Record: Both ingredients have been used for many years, and their common side effects are well documented.

6. Easy to Carry and Track: A strip of 15 tablets is compact. A fixed daily schedule, such as one tablet after breakfast and one after dinner if your doctor advises, makes adherence easy to monitor.

Who Should Take This Medicine?

Your doctor may prescribe it if:

• You are an adult with type 2 diabetes
• Your blood sugar is not controlled with diet, exercise and one medicine
• You already take vildagliptin and metformin separately and a combination is suitable
• You tolerate metformin at the dose in this tablet and have adequate kidney function

It is not for type 1 diabetes or diabetic ketoacidosis, and not for children unless a doctor specifically advises it.

How to Take VILDIABATE M 1000

• Take it exactly as prescribed. Do not change the dose or timing on your own.
• Take it with or just after a meal to reduce stomach upset from metformin.
• Swallow the tablet whole with water. Do not crush or chew it unless your doctor says so, and follow the pack label if it states a sustained-release form.
• If you miss a dose, take it when you remember unless the next dose is almost due. Never double up.
• Keep up your diet, exercise and scheduled blood sugar, HbA1c, liver and kidney tests.

Precautions: What to Know Before and While Taking It

Do Not Use If You Have

• Type 1 diabetes or diabetic ketoacidosis
• Severe kidney impairment or are on dialysis, because metformin is not suitable at low kidney function
• Active liver disease or significantly raised liver enzymes
• Metabolic acidosis or a history of lactic acidosis
• An allergy to vildagliptin, metformin or any ingredient

Tell Your Doctor Before Starting If You

• Have kidney, liver or heart problems, including heart failure
• Have had pancreatitis or severe, persistent abdominal pain
• Drink alcohol regularly, which raises the risk of lactic acidosis
• Are dehydrated, or have ongoing vomiting or diarrhoea
• Are pregnant, planning pregnancy or breastfeeding, as this medicine is generally not recommended
• Take insulin, sulfonylureas, ACE inhibitors or any other medicine or supplement

Possible Side Effects

Not everyone gets side effects, and many mild ones settle within a few weeks.

Common

• Nausea, vomiting, diarrhoea, bloating or stomach discomfort
• Loss of appetite or a metallic taste
• Headache or dizziness
• Tremor or feeling shaky
• Low blood sugar, especially if taken with insulin or sulfonylureas
• Cold-like symptoms such as a stuffy nose or sore throat

Frequently Asked Questions 

1. Can I take Vildagliptin and Metformin tablets with food?

Yes. Vildagliptin and Metformin tablets are generally taken with or just after meals to help reduce stomach-related side effects, such as nausea and diarrhoea. Follow your doctor's instructions and the directions for your specific formulation.

2. Can I order Vildagliptin and Metformin tablets online?

Yes, Vildagliptin and Metformin tablets may be available through licensed online pharmacies and authorised pharmaceutical suppliers in India. Check the brand, strength, pack size, seller credentials, and prescription requirements before ordering.

3. Is Vildagliptin and Metformin a prescription medicine in India?

Yes. This combination is used to manage type 2 diabetes and should be taken under the supervision of a qualified healthcare professional. Consult your doctor before starting treatment, changing the dose, or switching brands.

4. Is Vildagliptin and Metformin safe for kidney patients?

It depends on the patient's kidney function and overall health. Metformin may not be suitable for people with severe kidney impairment, and the dose may need adjustment in some cases. Kidney function should be assessed before and during treatment. People with kidney disease should consult their doctor before using this combination.

5. Is Vildagliptin and Metformin available in India?

Yes, combination products containing Vildagliptin and Metformin are available in India under different brand names and strengths. Availability may vary by pharmacy and location. Check with a licensed pharmacy for the specific formulation prescribed by your doctor.

6. Does Vildagliptin and Metformin cause weight loss?

Weight loss is not a guaranteed effect of Vildagliptin and Metformin. Metformin is generally considered weight-neutral or may lead to modest weight loss in some people, while Vildagliptin is usually weight-neutral. Follow your doctor's advice on diet, physical activity, and weight management.

7. Does Vildagliptin and Metformin cause frequent urination?

Frequent urination is not a typical direct effect of this combination. However, high blood glucose levels can cause frequent urination and increased thirst. If these symptoms continue, consult your doctor to check your blood sugar and assess whether your treatment needs adjustment.

8. What are the side effects of Vildagliptin and Metformin?

Possible side effects include nausea, diarrhoea, vomiting, abdominal discomfort, headache, and dizziness. Low blood sugar may occur, especially when the combination is used with insulin or certain other diabetes medicines.

Rare but serious risks include lactic acidosis associated with Metformin, liver problems, and inflammation of the pancreas. Seek urgent medical attention for severe or persistent abdominal pain, repeated vomiting, unusual weakness, or difficulty breathing. Contact your doctor if you notice yellowing of the skin or eyes.

9. What should I avoid while taking Vildagliptin and Metformin?

Avoid excessive alcohol consumption because it can increase the risk of lactic acidosis associated with Metformin. Do not take extra doses, change your dose, or add other diabetes medicines without medical advice. Maintain adequate hydration and follow your prescribed meal plan.

Tell your doctor about all medicines and supplements you take. Inform your healthcare team if you develop severe vomiting or diarrhoea, become seriously ill, or are scheduled for surgery or an imaging procedure involving contrast dye, as temporary treatment adjustments may be needed.

10. How should I take Vildagliptin and Metformin safely?

Take the medicine exactly as prescribed, generally with or just after meals. Follow the instructions for your specific formulation, monitor your blood glucose as advised, and attend recommended kidney-function and liver-function checks. Do not stop or change treatment without consulting your doctor.