UDCHOLIC 600 SR

UDCHOLIC 600 SR

UDCHOLIC 600 SR is a sustained-release formulation containing Ursodeoxycholic Acid (UDCA) 600 mg, a naturally occurring bile acid with proven hepatoprotective and choleretic properties. It is specifically designed for the management of cholestatic liver disorders, gallstone dissolution, and improvement of liver function in chronic liver diseases.

Manufactured under stringent Good Manufacturing Practices (GMP), UDCHOLIC 600 SR ensures consistent bioavailability, controlled release, and effective therapeutic action over an extended duration.

Composition

• Active Ingredient: Ursodeoxycholic Acid 600 mg (Sustained Release)

• Dosage Form: Film-coated sustained-release tablet

Key Indications

UDCHOLIC 600 SR is indicated for:

• Cholestatic Liver Diseases: Including primary biliary cholangitis (PBC), primary sclerosing cholangitis (PSC), and intrahepatic cholestasis.

• Gallstone Dissolution: For the dissolution of small, radiolucent cholesterol gallstones in patients with functioning gallbladders.

• Fatty Liver and Hepatobiliary Disorders: As adjunctive therapy to improve liver enzyme profiles and bile flow.

• Post-Liver Transplant Support: To prevent bile stasis and improve graft function.

Mechanism of Action

Ursodeoxycholic Acid (UDCA) is a hydrophilic bile acid that exerts multiple hepatoprotective actions:

• Choleretic Effect: Increases bile flow and reduces bile viscosity, aiding in detoxification.

• Cytoprotective Action: Stabilizes hepatocyte membranes against bile acid-induced injury.

• Immunomodulatory Properties: Reduces autoimmune-mediated hepatic inflammation.

• Cholesterol-Lowering in Bile: Decreases cholesterol saturation, leading to gradual dissolution of cholesterol gallstones.

In sustained-release form, UDCHOLIC 600 SR provides prolonged therapeutic levels, ensuring steady hepatic exposure and enhanced patient compliance.

Dosage and Administration

• Recommended Dose: One tablet of UDCHOLIC 600 SR (600 mg) once daily, preferably with food.

• In Gallstone Dissolution: Dose and duration depend on the size and number of gallstones (typically 6–24 months).

• In Chronic Liver Diseases: As prescribed by a healthcare professional, usually continued long-term for optimal liver protection.

Dosage adjustments may be necessary based on patient response, disease severity, or physician’s assessment.

Key Benefits of UDCHOLIC 600 SR

• Sustained-Release Formula: Ensures consistent drug levels with once-daily dosing.

• Hepatoprotective Action: Protects liver cells from bile acid toxicity and oxidative stress.

• Improved Bile Flow: Reduces cholestasis and associated symptoms like jaundice and itching.

• Clinically Proven Efficacy: Supported by extensive research in the management of chronic liver diseases.

• Enhanced Patient Compliance: Convenient once-daily dosing improves adherence to therapy.

Safety and Precautions

• Liver Function Monitoring: Regular monitoring of liver enzymes is recommended during long-term use.

• Gallstone Assessment: Periodic ultrasound scans are advised when used for gallstone dissolution.

• Contraindications:

  • Acute inflammation of the gallbladder or biliary tract

  • Obstruction of the bile ducts

  • Radiopaque (calcified) gallstones

  • Hypersensitivity to Ursodeoxycholic Acid

• Pregnancy and Lactation: Use only if clearly indicated and prescribed by a physician.

• Pediatric Use: Safety in children has not been fully established for the sustained-release form.

Possible Side Effects

UDCHOLIC 600 SR is generally well-tolerated. However, some patients may experience:

• Mild diarrhea or loose stools

• Abdominal pain or discomfort

• Nausea

• Skin rash (rare)

• Elevated liver enzymes (rare; monitor periodically)

If any side effects persist or worsen, discontinue use and consult a healthcare professional.

Storage Instructions

• Store below 30°C, in a cool, dry place.

• Protect from light and moisture.

• Keep out of reach of children.

Why Choose UDCHOLIC 600 SR?

UDCHOLIC 600 SR provides a trusted, sustained-release solution for long-term management of cholestatic and hepatobiliary disorders. Its once-daily formulation enhances patient convenience, while its clinically proven efficacy ensures reliable liver protection and improved bile function.

Manufactured under GMP-certified facilities, every tablet of UDCHOLIC 600 SR meets the highest pharmaceutical quality standards, making it a dependable choice for physicians and patients alike.

Disclaimer

This information is provided for educational and informational purposes only and should not replace professional medical advice. Always consult your doctor or healthcare provider before starting any new medication.