TOLVAPTORIS 30

TOLVAPTORIS 30 is a pharmaceutical medication containing the active ingredient tolvaptan 30 mg. This medication is specifically designed to manage conditions related to abnormal low sodium levels in the blood, which can be a serious complication in patients with certain medical disorders. Tolvaptan 30 mg is a vasopressin receptor antagonist that works by increasing the excretion of free water, thus helping to restore the balance of sodium in the bloodstream. This action helps alleviate symptoms associated with hyponatremia and prevents further complications.

What is TOLVAPTORIS 30?

TOLVAPTORIS 30 is a prescription drug that contains tolvaptan 30 mg as its active component. It belongs to a class of medications known as vasopressin V2-receptor antagonists. It functions by blocking antidiuretic hormone (ADH) effects in the kidneys, thereby promoting water excretion without losing electrolytes such as sodium. This helps increase blood sodium levels in patients where sodium is abnormally low.

Uses of TOLVAPTORIS 30

• Treatment of hyponatremia (low sodium levels in the blood) associated with heart failure.

• Management of hyponatremia caused by the syndrome of inappropriate antidiuretic hormone secretion (SIADH).

• Used in conditions where water retention and low sodium become life-threatening or symptomatic.

• May also be prescribed under specialist advice for certain kidney disorders linked with fluid imbalance.

Side Effects of TOLVAPTORIS 30

While TOLVAPTORIS 30 is effective, it can cause certain side effects which may vary in severity:

• Increased thirst

• Dry mouth

• Frequent urination

• Fatigue or weakness

• Constipation

• Nausea

• Dehydration, especially in older adults or those unable to drink adequately

• Elevated liver enzymes or risk of liver damage with prolonged use

• Serious allergic reactions (e.g., swelling, difficulty breathing) are rare but require immediate medical attention

• Possible confusion, dizziness, or muscle weakness related to rapid changes in sodium levels

Precautions Before Using TOLVAPTORIS 30

• Inform your doctor if you have liver disease, kidney problems, or an electrolyte imbalance before starting this medication.

• Avoid grapefruit juice as it can interfere with how tolvaptan is metabolized.

• Close monitoring of liver function tests is essential during treatment to detect early signs of liver injury.

• Adequate hydration is important to prevent dehydration.

• This drug should be used under strict medical supervision due to risks associated with rapidly correcting sodium levels.

• Not recommended during pregnancy or breastfeeding without a doctor’s approval.

Drug Interactions: What Drugs Interact with TOLVAPTORIS 30?

• Certain antifungal medications (e.g., ketoconazole) and antibiotics (e.g., clarithromycin) may increase tolvaptan levels.

• Drugs that affect liver enzymes such as CYP3A4 inhibitors or inducers can alter tolvaptan blood concentrations.

• Caution is advised when used with diuretics or other medications affecting electrolytes and kidney function.

• Always inform your healthcare provider about all medications, supplements, or herbal products you are taking to avoid potential interactions.

Tolvaptan is used to treat hyponatremia (low sodium in the blood) in patients with heart failure or syndrome of inappropriate antidiuretic hormone (SIADH).

This medication plays a crucial role in correcting sodium imbalance by promoting water loss while retaining sodium, thereby improving symptoms and preventing complications related to low blood sodium.