TENELIGOLD PM 1000

TENELIGOLD PM 1000 is a combination of Teneligliptin 20 mg, Pioglitazone 15 mg, and Metformin Hydrochloride (Sustained Release) 1000 mg Tablets, formulated to help manage Type 2 Diabetes Mellitus (T2DM) in adults. This triple-drug combination is designed to provide comprehensive glycemic control by targeting different mechanisms responsible for elevated blood glucose levels.

Manufactured with high-quality pharmaceutical standards, TENELIGOLD PM 1000 helps improve insulin sensitivity, enhances insulin secretion in a glucose-dependent manner, and reduces excessive glucose production by the liver. It is commonly prescribed when diet, exercise, and monotherapy fail to achieve adequate blood sugar control.

Composition

Each sustained-release tablet contains:

• Teneligliptin – 20 mg
• Pioglitazone – 15 mg
• Metformin Hydrochloride (Sustained Release) – 1000 mg

Dosage Form: Sustained Release Tablets

How TENELIGOLD PM 1000 Works

TENELIGOLD PM 1000 combines three clinically proven antidiabetic medicines that work together for better glucose management.

1. Teneligliptin 20 mg

Teneligliptin belongs to the DPP-4 inhibitor class. It increases incretin hormone levels, which:

• Stimulate insulin release only when blood glucose levels are high
• Reduce glucagon secretion
• Lower post-meal blood sugar spikes
• Minimize the risk of hypoglycemia

2. Pioglitazone 15 mg

Pioglitazone is a Thiazolidinedione (TZD) that:

• Improves insulin sensitivity
• Helps muscles utilize glucose more efficiently
• Reduces insulin resistance
• Supports long-term glycemic control

3. Metformin SR 1000 mg

Metformin SR is a Biguanide that:

• Reduces glucose production in the liver
• Decreases intestinal glucose absorption
• Improves insulin sensitivity
• Provides prolonged blood sugar control throughout the day

The sustained-release formulation also helps improve gastrointestinal tolerability compared to immediate-release formulations.

Benefits of TENELIGOLD PM 1000

TENELIGOLD PM 1000 offers multiple therapeutic benefits for patients with Type 2 Diabetes.

Effective Blood Sugar Management

The triple-action formula helps maintain both fasting and postprandial blood glucose levels.

Better HbA1c Reduction

The combination therapy may provide greater HbA1c reduction compared with single-drug treatment, when prescribed appropriately.

Improves Insulin Sensitivity

Pioglitazone helps reduce insulin resistance, making insulin more effective.

Sustained Glucose Control

Metformin SR provides gradual drug release, ensuring consistent blood glucose management.

Convenient Triple Combination

Three proven antidiabetic medicines in a single tablet improve treatment convenience and may support better adherence.

Supports Long-Term Diabetes Care

Maintaining good glycemic control may help reduce the risk of diabetes-related complications when combined with lifestyle changes.

Indications

TENELIGOLD PM 1000 is indicated as an adjunct to diet and exercise for improving glycemic control in adults with Type 2 Diabetes Mellitus, particularly when combination therapy is appropriate based on a physician's assessment.

It is not indicated for Type 1 Diabetes Mellitus or diabetic ketoacidosis.

Key Features

• Triple combination antidiabetic tablet
• Sustained Release Metformin formulation
• Helps control fasting and post-meal blood sugar
• Improves insulin sensitivity
• Enhances glucose-dependent insulin secretion
• Reduces hepatic glucose production
• Convenient once-daily dosing, if prescribed
• Manufactured under stringent quality standards
• Suitable for long-term diabetes management under medical supervision

Who May Benefit?

Healthcare professionals may prescribe TENELIGOLD PM 1000 for adults with Type 2 Diabetes who:

• Have uncontrolled blood sugar despite dual therapy
• Require improved HbA1c management
• Have significant insulin resistance
• Need comprehensive glycemic control
• Benefit from a sustained-release metformin formulation

Treatment decisions should always be individualized by the prescribing physician.

Directions for Use

• Take the tablet exactly as prescribed by your doctor.
• Swallow the tablet whole with water.
• Do not crush, chew, or break the sustained-release tablet.
• It is generally recommended to take the medicine with food to reduce gastrointestinal discomfort.
• Follow your prescribed diet and exercise regimen for optimal results.

Possible Side Effects

Like all medicines, TENELIGOLD PM 1000 may cause side effects, although not everyone experiences them.

Common side effects may include:

• Nausea
• Diarrhea
• Stomach discomfort
• Headache
• Mild weight gain
• Peripheral edema (swelling), particularly due to pioglitazone

Serious but less common risks include:

• Lactic acidosis (associated with metformin, especially in susceptible individuals)
• Heart failure exacerbation (with pioglitazone in certain patients)
• Allergic reactions
• Liver function abnormalities

Patients should seek immediate medical attention if they experience symptoms such as severe weakness, difficulty breathing, chest pain, or persistent abdominal pain.

Precautions

Before using TENELIGOLD PM 1000, inform your healthcare provider if you have:

• Kidney disease
• Liver disease
• Heart failure
• Bladder cancer (current or history)
• Pancreatitis
• Vitamin B12 deficiency
• Severe dehydration
• Upcoming surgery or imaging procedures requiring iodinated contrast

Regular monitoring of blood glucose, HbA1c, kidney function, liver function, and other relevant parameters is recommended.

Storage Instructions

• Store below 30°C.
• Protect from moisture and direct sunlight.
• Keep in the original packaging.
• Keep out of reach of children.

Why Choose TENELIGOLD PM 1000?

TENELIGOLD PM 1000 combines three well-established antidiabetic medicines into a single sustained-release tablet, helping healthcare professionals simplify treatment while addressing multiple aspects of Type 2 Diabetes management. The combination supports comprehensive blood sugar control through complementary mechanisms of action, making it a valuable option for appropriately selected adult patients under medical supervision.

Frequently Asked Questions (FAQs)

What is TENELIGOLD PM 1000 used for?

TENELIGOLD PM 1000 is prescribed for the management of Type 2 Diabetes Mellitus in adults whose blood sugar levels require combination therapy alongside diet and exercise.

Can TENELIGOLD PM 1000 be taken daily?

Yes. It should be taken exactly as prescribed by your physician. Do not change the dose without medical advice.

Does TENELIGOLD PM 1000 cause hypoglycemia?

When used alone, the risk of hypoglycemia is generally low. However, the risk may increase if combined with insulin or sulfonylureas.

Can I stop taking the medicine once my sugar becomes normal?

No. Diabetes is a chronic condition. Continue taking the medicine unless your doctor advises otherwise.

Is TENELIGOLD PM 1000 suitable for Type 1 Diabetes?

No. It is intended only for adults with Type 2 Diabetes Mellitus.

Can I take TENELIGOLD PM 1000 with meals?

Yes. It is usually recommended to take the tablet with food to reduce stomach-related side effects.

Does this medicine help reduce HbA1c?

Yes. When used as prescribed along with lifestyle modifications, TENELIGOLD PM 1000 can help improve HbA1c and overall glycemic control.