STARGAB 400
Item requires a valid prescription
Manufactured By Steris Healthcare Pvt. Ltd.
Composition Gabapentin Tablets IP
Rs 203.50
MRP Rs 290.00
(30% OFF)
Includes all taxes
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( For 10 Tablets )
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Description:
STARGAB 400 is a prescription medication that contains Gabapentin 400 mg, formulated to provide effective relief from neuropathic pain and to aid in the management of partial seizures. Manufactured under stringent Good Manufacturing Practices (GMP), STARGAB 400 delivers consistent therapeutic results, ensuring high-quality standards and patient safety. Its clinically proven efficacy, tolerability, and broad range of neurological applications make it a trusted choice among healthcare professionals across India.
Composition
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Active Ingredient: Gabapentin 400 mg
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Dosage Form: Film-coated oral tablet
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Therapeutic Class: Anticonvulsant / Neuropathic Pain Modulator
Each tablet of STARGAB 400 contains the active pharmaceutical ingredient Gabapentin, a structural analog of gamma-aminobutyric acid (GABA), designed to act on the central nervous system (CNS) to reduce abnormal nerve excitability.
Pharmacological Profile
Gabapentin, the active component of STARGAB 400, is a GABA analog that modulates neurotransmitter release in the brain. Although its structure is related to GABA, it does not bind directly to GABA receptors. Instead, it interacts with the alpha-2-delta subunit of voltage-gated calcium channels in the CNS. By doing so, Gabapentin reduces the release of excitatory neurotransmitters such as glutamate, noradrenaline, and substance P, leading to a calming effect on nerve activity and pain signaling.
This mechanism helps alleviate neuropathic pain, a chronic pain condition resulting from nerve damage, and aids in seizure control in patients with epilepsy.
Mechanism of Action
STARGAB 400 works through multiple mechanisms to stabilize nerve activity and relieve pain:
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Calcium Channel Modulation:
Gabapentin binds to the alpha-2-delta subunit of voltage-dependent calcium channels in the brain, reducing calcium influx and suppressing excessive neuronal firing. -
Neurotransmitter Regulation:
It modulates the release of excitatory neurotransmitters responsible for pain transmission and seizure generation. -
Pain Signal Interruption:
Gabapentin interrupts pain signals between the damaged nerves and the brain, making it especially effective for conditions like diabetic neuropathy, postherpetic neuralgia, and sciatica. -
Anticonvulsant Effect:
By stabilizing electrical activity in the brain, it helps prevent abnormal nerve impulses that cause seizures.
Therapeutic Indications
STARGAB 400 is indicated for the following medical conditions:
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Neuropathic Pain Disorders
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Diabetic Peripheral Neuropathy
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Postherpetic Neuralgia (pain following shingles)
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Trigeminal Neuralgia
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Sciatica and Radiculopathy
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Nerve Pain due to Spinal Cord Injury
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Epilepsy and Seizure Disorders
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Partial seizures with or without secondary generalization
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Adjunctive therapy in adult and pediatric epilepsy
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Fibromyalgia and Chronic Pain Conditions
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Helps manage chronic nerve-related pain and improves quality of life.
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Restless Legs Syndrome (off-label use)
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May help relieve uncomfortable sensations and improve sleep quality.
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Key Benefits of STARGAB 400
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Effective Neuropathic Pain Relief:
STARGAB 400 provides targeted relief from chronic nerve pain, improving comfort and mobility. -
Reliable Seizure Control:
Offers adjunctive therapy for partial seizures, reducing seizure frequency and severity. -
Improves Sleep Quality:
Gabapentin’s ability to reduce nerve pain and calm neural activity promotes better sleep in patients with neuropathic disorders. -
Well-Tolerated Formula:
Has a proven safety record with minimal risk of drug interactions compared to older anticonvulsants. -
Long-Term Management:
Suitable for continuous use under medical supervision for chronic neurological conditions. -
Enhanced Quality of Life:
Reduces pain, improves functionality, and supports emotional well-being in patients suffering from long-term neuropathic pain.
Dosage and Administration
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Usual Adult Dose:
The initial dose is typically 300 mg once daily, which may be gradually increased to 400 mg three times daily depending on individual response and tolerance.
STARGAB 400 should be taken as directed by a healthcare professional. -
Method of Administration:
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Swallow the tablet whole with water.
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It can be taken with or without food.
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Maintain a consistent dosing schedule for best results.
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Adjustment:
In elderly patients or those with kidney impairment, dosage adjustments may be required based on renal function. -
Discontinuation:
Do not abruptly stop taking STARGAB 400, as it may cause withdrawal symptoms or increase seizure risk. Always taper down under medical guidance.
Safety and Precautions
While STARGAB 400 is well-tolerated, precautions must be observed to ensure safety:
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Renal Impairment:
Dose modification may be necessary, as Gabapentin is excreted through the kidneys. -
CNS Depression:
May cause dizziness, somnolence, or coordination issues. Avoid driving or operating machinery until the response to therapy is known. -
Alcohol Interaction:
Avoid alcohol consumption as it can enhance sedative effects and increase dizziness or drowsiness. -
Pregnancy and Lactation:
Use only if clearly indicated. The potential risks and benefits should be assessed by the physician. -
Psychiatric Effects:
Monitor for mood changes, irritability, or suicidal ideation during treatment, especially in patients with a history of depression.
Possible Side Effects
STARGAB 400 is generally safe but may occasionally cause mild to moderate side effects, including:
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Dizziness or drowsiness
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Fatigue or weakness
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Nausea or vomiting
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Peripheral edema (swelling of legs)
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Tremors or unsteady gait
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Visual disturbances
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Weight gain or increased appetite
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Mild mood changes or anxiety
These effects are usually temporary and subside as the body adjusts to the medication. However, any severe or persistent adverse reaction should be promptly reported to a healthcare professional.
Drug Interactions
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Antacids: May reduce Gabapentin absorption; take STARGAB 400 at least 2 hours after antacid administration.
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Opioids and Sedatives: Concurrent use can increase sedation and respiratory depression risk.
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Other Antiepileptics: Generally safe, but dose adjustments may be needed for optimal seizure control.
Storage and Handling
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Store below 30°C in a cool, dry place.
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Keep the tablets in their original packaging, protected from moisture and direct sunlight.
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Keep out of reach of children.
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Do not use after the expiry date mentioned on the pack.
Why Choose STARGAB 400?
STARGAB 400 (Gabapentin Tablets IP 400 mg) offers a comprehensive approach to neuropathic pain management and seizure control. It provides targeted relief through nerve stabilization and neurotransmitter modulation, addressing both the cause and symptoms of neurological disorders.
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High-Quality Manufacturing: Produced under GMP-certified conditions ensuring consistent potency and safety.
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Proven Efficacy: Backed by extensive clinical data in neuropathic and seizure disorders.
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Better Tolerability: Minimal side effects compared to older anticonvulsants.
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Flexible Dosing: Suitable for both acute and chronic management.
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Trusted by Neurologists: Recognized as a reliable first-line option for neuropathic pain and adjunctive seizure therapy.
By effectively reducing pain, preventing seizures, and promoting nerve health, STARGAB 400 significantly enhances patient quality of life.