ST-GLIPTIN M 100/ 1000

ST-GLIPTIN M 100/1000 is a prescription tablet from Steris Healthcare Pvt. Ltd. that combines sitagliptin and metformin hydrochloride in one tablet. It is prescribed, along with diet and exercise, to help control blood sugar in adults with type 2 diabetes mellitus. The two medicines work in complementary ways. Sitagliptin belongs to the DPP-4 inhibitor group. It helps the body keep higher levels of natural incretin hormones, which prompt the pancreas to release insulin when blood sugar rises after a meal and reduce the amount of sugar released by the liver. Metformin, a biguanide, lowers the amount of glucose the liver produces and helps the body respond better to its own insulin. Doctors in India commonly choose sitagliptin and metformin hydrochloride tablets when metformin alone, or sitagliptin alone, has not brought blood sugar into the target range. It is not a treatment for type 1 diabetes and does not cure diabetes. It must be taken only as your doctor directs.

Product Information 

Why Is It Important?

India is home to one of the largest populations of people living with diabetes in the world, and national studies such as ICMR-INDIAB suggest that many millions more have prediabetes.Type 2 diabetes usually progresses over time, so a single medicine often stops being enough, and doctors add a second drug with a different action to keep blood sugar in range. Good control matters because persistently high blood sugar can quietly damage the eyes, kidneys, nerves, heart and blood vessels. A fixed-dose combination tablet can make daily treatment simpler, since one tablet replaces two, and simpler routines are easier to stick with. This is especially helpful for people who take several medicines for blood pressure, cholesterol or other conditions. Sitagliptin has a low tendency to cause low blood sugar on its own, which is a point doctors consider when choosing treatment. Medicine works best alongside a balanced diet, regular physical activity, weight management and regular check-ups of blood sugar, HbA1c and kidney function. Please never start, stop or change your diabetes medicine without your doctor’s advice.

Key Benefits

• Helps lower both fasting and after-meal blood sugar through two different actions
• Sitagliptin supports the body’s own insulin response when blood sugar rises
• Metformin reduces sugar production by the liver and improves insulin sensitivity
• Combination therapy may help when one medicine alone has not achieved the blood sugar target, as judged by the doctor
• Sitagliptin has a low risk of causing low blood sugar when used without insulin or sulfonylureas
• Metformin is generally weight-neutral, and sitagliptin has little effect on body weight
• One tablet instead of two, which simplifies the daily routine and may support adherence
• Suited to long-term use under regular medical supervision
• Made by Steris Healthcare, a WHO-GMP and ISO 9001 certified manufacturer
• Compact 15-tablet strip for easy tracking of supply

Precautions

• Take only on the advice of a registered medical practitioner, at the dose prescribed
• Take with meals, as directed, to reduce stomach upset
• Do not use if you have type 1 diabetes or diabetic ketoacidosis
• Do not use if you are allergic to sitagliptin, metformin or any ingredient of the tablet
• Do not use in severe kidney impairment, and tell your doctor about any kidney problem, as metformin is cleared by the kidneys and sitagliptin dosing may need adjustment
• Tell your doctor if you have liver disease, heart failure, a history of pancreatitis, gallstones or very high triglycerides
• Metformin carries a rare risk of lactic acidosis, which is higher with dehydration, severe infection, heavy alcohol use, and kidney, liver or heart problems
• Avoid alcohol, which raises the risk of lactic acidosis and affects blood sugar
• Tell your doctor and the radiology team before any scan using iodinated contrast dye, and before any surgery, as metformin may need to be paused temporarily

Side Effects

• Nausea, vomiting or loss of appetite
• Diarrhoea, stomach discomfort, bloating or gas
• Metallic taste in the mouth
• Headache
• Runny nose, sore throat or other upper respiratory symptoms
• Mild low blood sugar when combined with insulin or sulfonylureas
• Lower vitamin B12 levels with long-term use
• Skin rash or itching

Frequently Asked Questions 

1. Where can I buy Sitagliptin and Metformin Hydrochloride Tablets online?

You can check licensed online pharmacies and authorized pharmaceutical suppliers in India for Sitagliptin and Metformin Hydrochloride Tablets. Before purchasing, verify the brand name, strengths, formulation, manufacturer details, and prescription requirements.

2. What is the price of Sitagliptin and Metformin Hydrochloride Tablets?

The price depends on the brand, strength of each ingredient, formulation, pack size, and seller. Contact an authorized pharmacy or check its current product listing for updated pricing and delivery charges.

3. Can I order Sitagliptin and Metformin Hydrochloride Tablets online?

Yes, you may be able to order these tablets through a licensed online pharmacy, subject to availability and prescription verification. Confirm the exact composition, pack size, expiry date, and delivery terms before placing your order.

4. Are Sitagliptin and Metformin Hydrochloride Tablets available from Steris Healthcare?

To confirm availability from Steris Healthcare Pvt. Ltd., visit the Sterispharma website or contact the company directly. Check the current stock, available strengths, pack size, and ordering procedure before purchasing.

5. What are Sitagliptin and Metformin Hydrochloride Tablets used for?

Sitagliptin and Metformin Hydrochloride Tablets are prescribed to help control blood glucose levels in adults with type 2 diabetes mellitus. Sitagliptin helps regulate incretin hormones involved in insulin release, while metformin reduces glucose production in the liver and improves the body's response to insulin. They are generally used alongside a suitable diet and exercise plan.

6. What is the composition of Sitagliptin and Metformin Hydrochloride Tablets?

These tablets contain two active ingredients: sitagliptin and metformin hydrochloride. The exact strengths vary by product. Some formulations contain immediate-release metformin, while others use extended-release formulations. Always check the product label or prescription to confirm the exact composition.

7. Is a prescription required for Sitagliptin and Metformin Hydrochloride Tablets?

Yes, these are prescription medicines in India. They should be used under medical supervision, with the dose selected according to blood glucose control, kidney function, other medicines, and individual treatment requirements.

8. How should Sitagliptin and Metformin Hydrochloride Tablets be taken?

Take the tablets exactly as prescribed by your doctor. They are often taken with meals to help reduce gastrointestinal discomfort, but timing depends on the specific formulation. Swallow extended-release tablets whole unless the product instructions state otherwise. Do not change the dose or stop treatment without medical advice.

9. What should I know before buying Sitagliptin and Metformin Hydrochloride Tablets?

Before buying, check the ingredient strengths, formulation, manufacturer, batch number, expiry date, and packaging integrity. Inform your doctor if you have kidney or liver problems, a history of pancreatitis, or other significant medical conditions. Metformin may be unsuitable in severe kidney impairment, and urgent medical attention is needed for symptoms suggestive of pancreatitis or lactic acidosis.

10. How can I order Sitagliptin and Metformin Hydrochloride Tablets online?

To order online, select a licensed pharmacy or authorized supplier, confirm the exact strengths and formulation prescribed, and complete the required prescription verification. Review the price, pack size, shipping charges, and delivery terms before checkout. You can also visit Sterispharma to enquire about availability from Steris Healthcare Pvt. Ltd.