ST GLIPTIN 3D 500

ST GLIPTIN 3D 500 is a scientifically formulated triple-combination oral anti-diabetic medication designed to provide comprehensive and sustained blood glucose control in adults with Type 2 Diabetes Mellitus. Combining Sitagliptin (100 mg), Metformin Hydrochloride (500 mg) Sustained Release, and Pioglitazone (15 mg), this powerful formulation addresses multiple underlying defects of diabetes in a single convenient tablet.

If you are looking for effective, well-balanced, and clinically trusted diabetes management therapy, ST GLIPTIN 3D 500 offers a complete solution that supports long-term glycemic stability and improved metabolic health.

What is ST GLIPTIN 3D 500?

ST GLIPTIN 3D 500 is a prescription medicine indicated for the management of Type 2 Diabetes Mellitus (T2DM) in adults. It is particularly beneficial for patients who:

• Are not adequately controlled with single or dual therapy

• Require triple oral therapy

• Need improved HbA1c control

• Prefer simplified medication regimens

This triple therapy combines three globally recognized anti-diabetic agents that work synergistically to regulate blood glucose levels effectively.

Composition of ST GLIPTIN 3D 500

Each tablet contains:

• Sitagliptin – 100 mg

• Metformin Hydrochloride – 500 mg (Sustained Release)

• Pioglitazone – 15 mg

This balanced combination ensures effective control of fasting blood glucose, postprandial glucose, and long-term HbA1c levels.

How ST GLIPTIN 3D 500 Works

Type 2 Diabetes is characterized by:

• Insulin resistance

• Decreased insulin secretion

• Increased hepatic glucose production

ST GLIPTIN 3D 500 targets all three key mechanisms simultaneously.

1. Sitagliptin 100 mg – DPP-4 Inhibitor

Sitagliptin belongs to the DPP-4 inhibitor class of anti-diabetic medications. It works by:

• Increasing incretin hormone levels

• Stimulating insulin secretion in response to meals

• Reducing excess glucagon release

• Improving post-meal glucose control

This mechanism helps lower blood sugar levels without causing significant hypoglycemia when used appropriately.

2. Metformin Hydrochloride 500 mg (Sustained Release)

Metformin is considered first-line therapy in Type 2 Diabetes management. The sustained-release (SR) formulation provides:

• Gradual release of medication

• Improved gastrointestinal tolerability

• Stable 24-hour glucose control

Metformin works by:

• Reducing hepatic glucose production

• Enhancing insulin sensitivity

• Improving peripheral glucose uptake

• Decreasing intestinal glucose absorption

The SR technology ensures smoother glycemic control with fewer GI disturbances compared to immediate-release forms.

3. Pioglitazone 15 mg – Insulin Sensitizer

Pioglitazone is a thiazolidinedione (TZD) that improves insulin sensitivity at the cellular level. It:

• Activates PPAR-gamma receptors

• Enhances glucose uptake in muscle and fat tissues

• Reduces insulin resistance

• Supports long-term metabolic stability

By addressing insulin resistance directly, Pioglitazone helps improve overall glucose utilization.

Key Benefits of ST GLIPTIN 3D 500

Triple-action glucose control
Effective HbA1c reduction
Sustained 24-hour blood sugar management
Reduced pill burden
Improved patient compliance
Balanced control of fasting and postprandial glucose
Clinically trusted active ingredients

Why Choose ST GLIPTIN 3D 500?

Comprehensive Approach to Diabetes

Unlike monotherapy, ST GLIPTIN 3D 500 tackles multiple metabolic defects simultaneously, leading to superior glycemic outcomes.

Convenient Single Tablet

Instead of taking three separate medications, patients benefit from one convenient formulation, improving adherence and simplifying therapy.

Sustained Release Advantage

The Metformin SR component ensures gradual drug release, reducing stomach-related side effects and providing prolonged action.

Suitable for Progressive Diabetes

Type 2 Diabetes is a progressive condition. As insulin resistance and beta-cell dysfunction increase, combination therapy becomes essential. ST GLIPTIN 3D 500 provides a step-up solution for better long-term control.

Indications

ST GLIPTIN 3D 500 is indicated for:

• Adults with Type 2 Diabetes Mellitus

• Patients inadequately controlled on dual therapy

• Individuals requiring triple oral therapy

• Patients seeking optimized glycemic management

It should be used alongside:

• Healthy diabetic diet

• Regular exercise

• Routine blood glucose monitoring

Dosage and Administration

• Take ST GLIPTIN 3D 500 exactly as prescribed by your healthcare professional.

• Usually taken once daily with meals.

• Swallow whole; do not crush or chew (due to sustained-release formulation).

• Follow your doctor’s instructions carefully for best results.

Expected Clinical Outcomes

With regular use and proper lifestyle management, ST GLIPTIN 3D 500 may help:

• Reduce HbA1c levels

• Lower fasting plasma glucose

• Improve postprandial blood sugar

• Enhance insulin sensitivity

• Maintain stable long-term glucose control

Patients may begin to see improvements within weeks, while full HbA1c benefits may take 8–12 weeks.

Safety Information

Like all medications, ST GLIPTIN 3D 500 may cause side effects in some individuals.

Common Side Effects:

• Mild gastrointestinal discomfort

• Headache

• Nasopharyngitis

• Mild weight changes

Less Common but Serious Risks:

• Lactic acidosis (rare, associated with Metformin)

• Fluid retention (associated with Pioglitazone)

• Allergic reactions

Seek immediate medical attention if you experience unusual symptoms such as persistent abdominal pain, severe weakness, or breathing difficulties.

Who Should Avoid ST GLIPTIN 3D 500?

Do not use this medication if you have:

• Severe kidney impairment

• Severe liver disease

• Type 1 Diabetes

• Diabetic ketoacidosis

• Known hypersensitivity to any component

Patients with heart failure history should consult a physician before use.

Pregnant or breastfeeding women should seek medical advice prior to taking this medication.

Lifestyle Recommendations for Best Results

For optimal glycemic control:

Maintain a Balanced Diet

Focus on:

• Low glycemic index foods

• High fiber intake

• Controlled carbohydrate portions

Exercise Regularly

Aim for:

• 30–45 minutes of moderate physical activity

• At least 5 days per week

Monitor Blood Sugar

Regular monitoring helps track progress and adjust therapy if needed.

Maintain Healthy Weight

Weight management improves insulin sensitivity and enhances medication effectiveness.

Storage Instructions

• Store below 25°C

• Keep in a cool, dry place

• Protect from moisture and sunlight

• Keep out of reach of children

Conclusion:

ST GLIPTIN 3D 500 is an advanced triple-action oral anti-diabetic formulation designed to provide effective and sustained blood glucose control in adults with Type 2 Diabetes Mellitus. With the combined strength of Sitagliptin 100 mg, Metformin Hydrochloride 500 mg Sustained Release, and Pioglitazone 15 mg, this medication addresses insulin secretion, insulin resistance, and excess glucose production simultaneously.