REVOSTATIN EZ 20

Revostatin EZ 20 is a fixed-dose combination of two lipid-lowering medicines in a single tablet. The "20" in the name refers to the rosuvastatin strength. The ezetimibe strength stays at 10 mg, the standard daily dose.

Think of cholesterol control as managing a tap and a drain at the same time:

• Rosuvastatin (the tap in your liver): It blocks the enzyme HMG-CoA reductase, which your liver uses to manufacture cholesterol. The liver compensates by pulling more LDL cholesterol out of the blood.
• Ezetimibe (the gate in your gut): It blocks the NPC1L1 transporter in the small intestine, which limits how much cholesterol from food and bile enters the body.

Because each ingredient acts on a different step, the combination lowers LDL more than raising the statin dose alone usually does. At the 20 mg rosuvastatin level, a statin already delivers substantial LDL reduction, and ezetimibe adds a further meaningful drop.

Where does the 20 mg strength fit? Revostatin EZ 20 is usually considered when a patient needs more LDL lowering than the 10 mg version provides. Your doctor makes this call based on your LDL level, your target, your overall cardiovascular risk and your tolerance. It is not meant as a starting point for everyone.

The tablet is manufactured by Steris Healthcare Pvt. Ltd., Jaipur, a WHO-GMP and ISO certified pharmaceutical company.

Product Information

Why Is Revostatin EZ 20 Important?

Cholesterol-related artery disease develops silently, often over decades. For many people, the first symptom is a heart attack or stroke. That is why targets matter more than symptoms.

1. Some patients need a lower LDL target. Guidelines set stricter LDL goals for people who already have heart disease, have had a stroke, or have diabetes with other risk factors. Reaching those goals can take more than a single mild-strength medicine.

2. India's risk profile is demanding. Heart disease tends to appear earlier in South Asians. Many Indians also carry a pattern of raised triglycerides, low HDL and small dense LDL particles, which can make cholesterol harder to control through diet alone.

3. A single medicine often plateaus. Doubling a statin dose usually gives only a few additional percentage points of LDL reduction. Adding ezetimibe works through a separate pathway and typically gives a further reduction of around 15 to 20%.

4. Evidence supports the approach. In the IMPROVE-IT trial, adding ezetimibe to a statin in patients after an acute coronary syndrome produced fewer cardiovascular events than the statin alone. The lower the LDL achieved, the better the protection.

5. Simplicity improves adherence. One tablet taken once a day is easier to continue for years than a regimen of several pills. Staying consistent is what protects your arteries.

A note for Asian patients: Rosuvastatin blood levels are roughly twice as high in people of Asian ancestry compared with other populations. Doctors therefore tend to be cautious with higher doses and monitor more closely. Never increase or switch strengths on your own.

Key Benefits 

• Stronger LDL lowering. The higher statin strength plus ezetimibe supports significant LDL reduction for patients who need it.
• Dual-action control. It tackles both cholesterol production and absorption.
• Helps high-risk patients reach goal. This includes people after a heart attack, those with diabetes, or those with a strong family history.
• Supports artery health. Lower LDL means less cholesterol deposited in artery walls over time.
• Possible alternative to very high statin doses. Combining ezetimibe may let doctors reach target without escalating the statin further.
• One tablet, once daily. Fewer pills and a simple routine.
• Reliable manufacturing. Produced by Steris Healthcare under WHO-GMP standards.

Uses of Revostatin EZ 20

Your doctor may consider this tablet:

• For primary hypercholesterolaemia or mixed hyperlipidaemia, alongside diet
• When LDL remains above target on a lower-strength statin or on Revostatin EZ 10
• For patients with established atherosclerotic cardiovascular disease needing intensive LDL reduction
• For selected patients with familial hypercholesterolaemia, under specialist care
• As a convenient replacement for taking rosuvastatin 20 mg and ezetimibe 10 mg as separate tablets, once the doses are established

A lipid profile and liver function test are normally checked before and during treatment.

Precautions: What to Know Before Taking 

Do not take this medicine if you:

• Are pregnant, planning pregnancy or breastfeeding
• Have active liver disease or unexplained, persistently raised liver enzymes
• Are allergic to rosuvastatin, ezetimibe or any ingredient in the tablet
• Are taking cyclosporine

Speak to your doctor first if you:

• Have kidney disease. Rosuvastatin levels rise in severe kidney impairment, and the 20 mg strength may not be suitable. Your doctor will decide.
• Are of Asian ancestry, as higher exposure to rosuvastatin is possible
• Are 65 or older
• Have an underactive thyroid that is not controlled
• Have had muscle pain or weakness with other cholesterol medicines
• Drink alcohol heavily or have a past liver problem
• Have diabetes or are at risk, because statins can slightly raise blood sugar
• Take other medicines or supplements, including antivirals and fibrates

Side Effects 

Many people take this combination without trouble. When side effects occur, they are usually mild.

Common:

• Headache
• Muscle aches or pain (myalgia)
• Abdominal discomfort
• Diarrhoea or constipation
• Nausea
• Fatigue

Less common:

• Dizziness
• Joint pain
• Skin rash or itching
• Raised liver enzymes on a blood test
• Slight rise in blood sugar
• Protein in the urine (more often with higher statin strengths)

Frequently Asked Questions

Where can I buy Rosuvastatin and Ezetimibe Tablets online?
You can buy Rosuvastatin and Ezetimibe Tablets online through a licensed pharmacy or authorized pharmaceutical supplier, subject to prescription requirements and product availability.

What is the price of Rosuvastatin and Ezetimibe Tablets?
The price may vary depending on the rosuvastatin and ezetimibe strengths, brand, pack size, seller, and applicable charges. Check the current product listing for the latest price.

Can I order Rosuvastatin and Ezetimibe Tablets online?
Yes, Rosuvastatin and Ezetimibe Tablets can generally be ordered online through an authorized pharmacy or pharmaceutical supplier when available. A valid prescription may be required.

Is Rosuvastatin and Ezetimibe Tablets available from Steris Healthcare?
Availability of Rosuvastatin and Ezetimibe Tablets from Steris Healthcare depends on the current product range and stock. Check the relevant product listing or contact Steris Healthcare for current availability.

What are Rosuvastatin and Ezetimibe Tablets used for?
Rosuvastatin and Ezetimibe Tablets are used to help lower elevated cholesterol levels, particularly LDL cholesterol. Rosuvastatin reduces cholesterol production in the liver, while ezetimibe reduces cholesterol absorption in the intestine.

What is the composition of Rosuvastatin and Ezetimibe Tablets?
Rosuvastatin and Ezetimibe Tablets contain rosuvastatin and ezetimibe as active ingredients. The exact strength of each ingredient depends on the specific formulation and should be verified on the product packaging.

Is a prescription required?
Yes, Rosuvastatin and Ezetimibe Tablets are prescription medicines and should be used under the supervision of a qualified healthcare professional.

How should Rosuvastatin and Ezetimibe Tablets be taken?
Take Rosuvastatin and Ezetimibe Tablets exactly as prescribed by your doctor. They are generally taken orally once daily, with or without food. Follow the prescribed dose and do not change or stop treatment without medical advice.

What should I know before buying Rosuvastatin and Ezetimibe Tablets?
Before buying, verify the strengths of rosuvastatin and ezetimibe, dosage form, pack size, manufacturer or marketer, expiry date, and storage instructions. Inform your doctor about liver or kidney problems, muscle-related conditions, pregnancy, allergies, and all medicines or supplements you are taking.

How can I order Rosuvastatin and Ezetimibe Tablets online?
To order Rosuvastatin and Ezetimibe Tablets online, select the required strength and pack size from an authorized pharmacy or supplier, provide a valid prescription if required, and complete the applicable payment and delivery process.