BUDESHINE PLUS 400

BUDESHINE PLUS 400 is a highly effective combination inhalation therapy designed for patients suffering from respiratory conditions such as asthma and Chronic Obstructive Pulmonary Disease (COPD). Manufactured by Steris Healthcare Pvt. Ltd., this medication brings together three powerful components—Budesonide, Glycopyrronium, and Formoterol Fumarate—to provide a synergistic approach in managing airway inflammation, bronchoconstriction, and mucus production.

In India, respiratory diseases are a growing concern, with increasing cases of asthma and COPD among both adults and children. BUDESHINE PLUS 400 serves as a reliable option for patients who require a triple-action inhalation therapy to maintain healthy lung function and reduce the risk of exacerbations.

Composition and Mechanism of Action

BUDESHINE PLUS 400 contains the following active ingredients:

1. Budesonide IP (400 mcg):

   • Budesonide is a corticosteroid that helps reduce inflammation in the airways. By decreasing swelling and irritation, it allows the lungs to function more efficiently. Budesonide is particularly effective in preventing asthma attacks and reducing chronic airway inflammation in COPD patients.

2. Glycopyrronium (25 mcg):

   • Glycopyrronium is a long-acting anticholinergic bronchodilator. It works by relaxing the muscles around the airways, preventing them from narrowing, and improving airflow. This component is particularly beneficial for patients with COPD who experience persistent breathing difficulties and chronic bronchospasm.

3. Formoterol Fumarate (12 mcg):

   • Formoterol is a long-acting beta-2 agonist (LABA) that quickly relaxes airway muscles, offering rapid relief from bronchoconstriction. It also improves exercise tolerance in patients with asthma or COPD. When combined with budesonide, it enhances overall symptom control and lung function.

The combination of these three agents in BUDESHINE PLUS 400 ensures both immediate relief from symptoms and long-term control of airway inflammation, making it an ideal choice for moderate to severe respiratory conditions.

Uses of BUDESHINE PLUS 400

BUDESHINE PLUS 400 is primarily prescribed for patients with chronic respiratory diseases. Its key uses include:

1. Asthma Management:

   • Helps in controlling persistent asthma symptoms, such as wheezing, shortness of breath, and coughing.

   • Reduces the frequency of asthma attacks by controlling airway inflammation.

2. Chronic Obstructive Pulmonary Disease (COPD):

   • Prevents COPD flare-ups by improving airflow and reducing bronchospasm.

   • Enhances exercise tolerance and daily functioning for COPD patients.

3. Bronchospasm Relief:

   • Provides rapid bronchodilation through formoterol, easing acute breathing difficulties.

4. Long-Term Respiratory Care:

   • Suitable for long-term management of moderate to severe asthma or COPD when monotherapy is insufficient.

Benefits of BUDESHINE PLUS 400

Using BUDESHINE PLUS 400 offers multiple benefits for patients seeking better respiratory health:

1. Triple-Action Therapy:

   • Combines anti-inflammatory, bronchodilator, and anticholinergic effects in a single inhaler.

2. Rapid and Sustained Relief:

   • Formoterol ensures quick symptom relief, while budesonide and glycopyrronium maintain long-term control.

3. Improved Lung Function:

   • Helps reduce airway obstruction, improve airflow, and increase oxygen intake.

4. Reduced Risk of Exacerbations:

   • Lowers the frequency and severity of asthma or COPD flare-ups.

5. Convenient and User-Friendly:

   • Available as an inhalation formulation suitable for home use under medical supervision.

6. Enhanced Quality of Life:

   • Patients experience fewer symptoms, better exercise tolerance, and improved daily activity levels.

Dosage and Administration

BUDESHINE PLUS 400 should be used strictly according to a doctor’s prescription. The typical dosage instructions include:

• Adult Dosage:

  • Usually prescribed 1 inhalation twice daily, morning and evening, or as directed by a physician.

• Pediatric Dosage:

  • Should be determined by a pediatrician based on age, weight, and severity of symptoms.

• Administration Tips:

  • Shake the inhaler well before use.

  • Exhale fully before inhaling the medication.

  • Inhale deeply and hold your breath for 10 seconds.

  • Rinse your mouth after use to prevent oral thrush.

Important: Never exceed the recommended dose. Overuse can lead to side effects, while underuse may reduce effectiveness.

Side Effects of BUDESHINE PLUS 400

Like all medications, BUDESHINE PLUS 400 may cause side effects in some patients. Common side effects include:

• Mouth and throat irritation or dryness

• Hoarseness or voice changes

• Cough immediately after inhalation

• Headache or dizziness

• Increased heart rate or palpitations

• Mild tremors

Rare but Serious Side Effects:

• Severe allergic reactions (rash, swelling, difficulty breathing)

• Signs of steroid-related complications such as adrenal suppression

Tip for Patients: Report any unusual or persistent side effects to your doctor immediately. Regular check-ups are recommended for long-term users.

Precautions and Warnings

Before using BUDESHINE PLUS 400, patients should follow these precautions:

1. Medical History:

   • Inform your doctor about any history of heart disease, high blood pressure, diabetes, glaucoma, or urinary retention.

2. Pregnancy and Lactation:

   • Consult a healthcare provider if you are pregnant, planning pregnancy, or breastfeeding.

3. Allergies:

   • Avoid use if you have a known allergy to budesonide, glycopyrronium, or formoterol.

4. Medication Interactions:

   • May interact with beta-blockers, diuretics, or other bronchodilators. Always inform your doctor about all medications being taken.

5. Usage Monitoring:

   • Long-term corticosteroid use requires periodic monitoring of lung function, blood pressure, and blood sugar levels.

6. Avoid Abrupt Discontinuation:

   • Do not stop using the inhaler suddenly without consulting your doctor.

Tips for Effective Use

• Use the inhaler at the same time every day to maintain consistent medication levels.

• Clean the mouthpiece regularly to prevent clogging and bacterial growth.

• Keep track of the number of doses used to avoid running out unexpectedly.

• Combine with pulmonary rehabilitation exercises and avoid smoking for optimal results.

Why Choose BUDESHINE PLUS 400

BUDESHINE PLUS 400 stands out in the Indian market for several reasons:

• Trusted Manufacturer: Steris Healthcare is renowned for quality, safety, and compliance with global pharmaceutical standards.

• Triple-Combination Therapy: Combines budesonide, glycopyrronium, and formoterol for enhanced symptom control.

• Proven Efficacy: Clinical studies have shown improved lung function, fewer exacerbations, and enhanced quality of life in patients with asthma and COPD.

• Patient-Centric Design: User-friendly inhaler format suitable for home management.

Conclusion

BUDESHINE PLUS 400 offers an advanced, all-in-one solution for asthma and COPD management. By combining anti-inflammatory, bronchodilator, and anticholinergic action, it addresses both short-term symptoms and long-term respiratory health.