ST GLIPTIN GM

ST GLIPTIN GM is primarily indicated for the management of Type 2 Diabetes Mellitus, especially in patients who require a combination of medicines for optimal blood sugar control.

It helps in:

• Lowering elevated blood glucose levels effectively in adults with type 2 diabetes.

• Improving insulin sensitivity and reducing hepatic glucose production.

• Supporting pancreatic insulin secretion in response to meals.

• Preventing diabetes-related complications such as neuropathy, nephropathy, and cardiovascular disease.

Mechanism of Action:

ST GLIPTIN GM works through a triple-action mechanism combining three potent anti-diabetic agents:

• Sitagliptin (DPP-4 Inhibitor):
  Inhibits the DPP-4 enzyme, increasing levels of incretin hormones (GLP-1 and GIP). This enhances insulin secretion and decreases glucagon release in a glucose-dependent manner.

• Metformin Hydrochloride (Biguanide):
  Reduces hepatic glucose production, improves peripheral insulin sensitivity, and slows intestinal glucose absorption, resulting in better glycemic control without causing weight gain.

• Glimepiride (Sulfonylurea):
  Stimulates pancreatic β-cells to secrete insulin, lowering fasting and post-meal blood glucose levels effectively.

This synergistic combination addresses multiple pathways of glucose regulation—making it highly effective for long-term diabetes management.

Dosage and Administration:

• Recommended Dose: As directed by your physician.
  (Typical strength: Sitagliptin 50 mg + Metformin 1000 mg + Glimepiride 1 mg.)

• Route: Oral, taken with water.

• Timing: Preferably once daily with meals to reduce gastrointestinal side effects.

• Adjustment: Dose may be adjusted depending on individual response, age, and kidney function.

Important: Always follow your doctor’s advice. Do not alter or stop the medicine without consultation.

Key Benefits of ST GLIPTIN GM:

• Provides comprehensive glucose control through a triple-mechanism approach.

• Reduces insulin resistance and promotes pancreatic efficiency.

• Decreases risk of hypoglycemia compared with some other combinations (due to glucose-dependent action of Sitagliptin).

• Improves HbA1c levels and fasting/postprandial blood glucose.

• Convenient once-daily dose enhances treatment compliance.

• Helps in preventing long-term complications of diabetes such as nerve, kidney, and eye damage.

• Well-tolerated with a favorable safety profile under medical supervision.

Safety and Precautions:

• Inform your doctor if you have kidney, liver, or heart disorders before starting the medication.

• Avoid in patients with severe renal impairment or metabolic acidosis.

• Not recommended for Type 1 Diabetes or diabetic ketoacidosis.

• Pregnant or breastfeeding women should use only if advised by a healthcare provider.

• Avoid excessive alcohol intake as it may increase the risk of lactic acidosis (from Metformin).

• Regular blood sugar and kidney function monitoring is recommended.

Possible Side Effects:

While ST GLIPTIN GM is generally well tolerated, some individuals may experience mild and temporary side effects:

Common:

• Nausea, diarrhea, or stomach discomfort

• Headache or dizziness

• Mild hypoglycemia (especially with missed meals)

• Fatigue

Rare but serious:

• Lactic acidosis (metformin-related)

• Pancreatitis (sitagliptin-related)

• Severe hypoglycemia

• Allergic reactions such as rash, swelling, or breathing difficulty

Seek medical attention immediately if any severe symptoms occur.

Storage Instructions:

• Store in a cool, dry place below 25 °C, away from direct sunlight and moisture.

• Keep out of reach of children.

• Do not use beyond the expiry date mentioned on the package.

Why Choose ST GLIPTIN GM:

• Developed by Steris Healthcare Pvt. Ltd, a trusted leader in quality and affordable pharmaceutical solutions.

• Manufactured with stringent quality control and clinical precision.

• Offers triple-therapy efficiency in one convenient tablet.

• Ensures consistent and sustained glucose control for diabetic patients.

• Designed to enhance treatment adherence and long-term health outcomes.

Disclaimer:

The information provided here is for educational purposes only.
ST GLIPTIN GM should be taken strictly under medical supervision.
Consult your doctor or healthcare professional for personalized advice, dosage adjustment, or management of any side effects.