CARDULES ISMN SR 50

CARDULES ISMN SR 50 is a sustained-release tablet formulated with Isosorbide Mononitrate (50 mg), a nitrate-class medication widely used for the prevention and long-term management of angina pectoris (chest pain caused by heart disease). This medicine works by relaxing and widening the blood vessels, ensuring an adequate oxygen supply to the heart muscles and reducing the workload on the heart. It is primarily prescribed to individuals suffering from coronary artery disease or chronic stable angina.

Key Benefits:

• Prevents angina attacks by increasing oxygen delivery to the heart muscles.

• Improves blood circulation by dilating the blood vessels, especially in the heart.

• Reduces the workload on the heart, making it easier for patients with heart conditions to engage in daily activities.

• Sustained-release formulation provides longer-lasting relief and maintains consistent therapeutic levels in the bloodstream.

• Helps manage chronic chest pain and enhances the overall quality of life in patients with heart-related conditions.

How Does It Work?

Isosorbide Mononitrate, the active component in CARDULES ISMN SR 50, is a nitrate that undergoes biotransformation to release nitric oxide (NO), a natural vasodilator. Nitric oxide activates guanylate cyclase, leading to the production of cyclic GMP, which relaxes the smooth muscles of the blood vessels. This action reduces preload and afterload, lowering the heart's oxygen demand and preventing anginal episodes. The sustained-release mechanism ensures a steady release of the drug over time, providing prolonged therapeutic effects and reducing the frequency of dosing.

Directions for Use:

• CARDULES ISMN SR 50 should be taken once daily, preferably in the morning after a light meal.

• Swallow the tablet whole with a glass of water. Do not crush or chew.

• Follow your healthcare provider's instructions regarding dosage and duration.

• Avoid abrupt discontinuation without consulting your doctor.

• Maintain a nitrate-free interval of 10–12 hours daily (as advised) to prevent tolerance buildup.

Side Effects:

While CARDULES ISMN SR 50 is generally well-tolerated, some individuals may experience:

• Headache – Common and usually resolves with continued use.

• Dizziness or lightheadedness – Especially when getting up from a sitting or lying position.

• Flushing or warmth in the face

• Low blood pressure (hypotension)

• Nausea or vomiting

• Fatigue or weakness

Seek immediate medical attention if you experience severe allergic reactions, chest pain that worsens, or signs of low blood pressure such as fainting or vision changes.

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