PREGABRIAL NT

PREGABRIAL NT is a combination of Pregabalin 75 mg and Nortriptyline 10 mg, formulated to treat various forms of neuropathic pain and nerve-related disorders. The combination works synergistically to relieve nerve pain by modulating nerve signals and improving mood-related symptoms often associated with chronic pain.This product is widely prescribed for conditions like diabetic neuropathy, sciatica, postherpetic neuralgia, and fibromyalgia. The blend of an anticonvulsant (pregabalin 75) and a tricyclic antidepressant (nortriptyline 10 mg) offers both pain relief and mood stabilization benefits.

What is PREGABRIAL NT?

PREGABRIAL NT is a fixed-dose tablet containing:

• Tab Pregabalin 75 mg: A gamma-aminobutyric acid (GABA) analog that reduces abnormal nerve signaling in the brain and spinal cord, helping to control seizures and neuropathic pain.

• Nortriptyline 10 mg tablet: A tricyclic antidepressant (TCA) that inhibits the reuptake of norepinephrine and serotonin, enhancing mood and reducing nerve sensitivity.

This combination is highly effective in chronic pain management, especially when pain has a neurological origin.

Uses of PREGABRIAL NT

PREGABRIAL NT (Pregabalin 75 nortriptyline 10) is used in the treatment of:

• Peripheral neuropathy (especially diabetic neuropathy)

• Postherpetic neuralgia (nerve pain following shingles)

• Fibromyalgia

• Chronic lower back pain with a neuropathic component

• Sciatica and radiculopathy

• Anxiety-related nerve pain or tension disorders

Patients often report improvement in both pain intensity and sleep quality.

Side Effects of Pregabalin 75 Nortriptyline 10

Like all medications, tab pregabalin 75 and nortriptyline 10 mg can cause side effects, although not everyone experiences them.

Common Side Effects:

• Drowsiness or dizziness

• Dry mouth

• Blurred vision

• Weight gain

• Constipation

• Increased appetite

Serious Side Effects (Less Common):

• Mood changes, suicidal thoughts

• Swelling of hands, feet (edema)

• Irregular heartbeat

• Severe allergic reactions (rare)

• Difficulty concentrating

Inform your doctor if side effects are persistent or bothersome.

Precautions Before Using

Before taking PREGABRIAL NT, consider the following:

• Use cautiously if you have a history of heart disease, especially arrhythmias

• Inform your doctor about kidney or liver impairment

• Avoid alcohol as it can increase drowsiness and other CNS side effects

• May not be suitable for elderly patients prone to falls or confusion

• Not recommended during pregnancy or breastfeeding unless clearly needed

• Should not be stopped abruptly—dose tapering is required to prevent withdrawal symptoms

Drug Interactions – What Drugs Interact with PREGABRIAL NT?

PREGABRIAL NT may interact with various drugs. Some of the most relevant interactions include:

Central Nervous System Depressants:

• Alcohol

• Benzodiazepines (e.g., diazepam, lorazepam)

• Opioids (e.g., morphine, tramadol)

• Other anticonvulsants or sedatives

These combinations may enhance drowsiness, dizziness, and risk of respiratory depression.

Antidepressants:

• SSRIs or SNRIs: Risk of serotonin syndrome when combined

• MAO inhibitors: Should be avoided within 14 days of nortriptyline use

Antihypertensive medications: May increase the risk of dizziness or orthostatic hypotension.

Always inform your healthcare provider of all medications, herbal products, and supplements you are taking before starting Pregabalin 75 nortriptyline 10 therapy.

Conclusion

PREGABRIAL NT, combining tab pregabalin 75 mg and nortriptyline 10 mg tablet, provides a clinically proven, effective approach for treating neuropathic pain and related disorders. The dual mechanism helps reduce nerve sensitivity while also addressing associated mood and sleep disturbances. For patients suffering from chronic nerve pain, PREGABRIAL NT offers targeted relief, improved quality of life, and better long-term outcomes when used under proper medical supervision.