OLMISTRUM CH 20

OLMISTRUM CH 20 is a fixed-dose combination anti-hypertensive medication formulated with Olmesartan Medoxomil IP (20mg) and Chlorthalidone IP (12.5mg). Manufactured and marketed in India by Steris Healthcare Pvt. Ltd. in 10-tablet blister strips, this targeted combination therapy provides effective, round-the-clock arterial blood pressure control for patients who require more than single-agent treatment.

Why Buy OLMISTRUM CH 20? Key Clinical Benefits

Uncontrolled hypertension is a leading contributor to heart attacks, strokes, heart failure, and progressive kidney damage. When single-drug therapy fails to reach target blood pressure levels, combining Olmesartan and Chlorthalidone offers distinct clinical advantages:

• Synergistic Blood Pressure Control: Combining two complementary anti-hypertensive agents lowers systemic vascular resistance and plasma volume more effectively than higher doses of either drug taken alone.

• Extended 24-Hour Protection: Chlorthalidone offers a significantly longer half-life than standard hydrochlorothiazide (HCTZ), maintaining steady blood pressure control throughout the night and early morning hours.

• Targeted Organ Protection: Olmesartan reduces intraglomerular pressure and systemic arterial stiffness, helping protect cardiac tissue and renal vascular beds from chronic pressure damage.

• Reduced Medication Burden: Combining two active ingredients into a single daily tablet simplifies treatment routines and improves daily compliance.

How OLMISTRUM CH 20 Works (Dual Mechanism of Action)

OLMISTRUM CH 20 addresses high blood pressure through two distinct, complementary pathways:

1. Olmesartan Medoxomil (20mg) – ARB

Olmesartan is an Angiotensin II Receptor Blocker. Angiotensin II is a hormone that binds to $AT_1$ receptors on vascular walls, causing blood vessels to constrict and stimulating aldosterone secretion (which promotes sodium and fluid retention). Olmesartan selectively blocks $AT_1$ receptors, preventing vasoconstriction and helping systemic blood vessels relax.

2. Chlorthalidone (12.5mg) – Thiazide-like Diuretic

Chlorthalidone acts on the distal convoluted tubule of the kidney to inhibit sodium ($\text{Na}^+$) and chloride ($\text{Cl}^-$) reabsorption. This increases the excretion of water and sodium, lowering extracellular fluid and plasma volume. Chlorthalidone's long duration of action (48–72 hours) keeps blood pressure controlled smoothly between daily doses.

Indications & Therapeutic Applications

OLMISTRUM CH 20 is prescribed across healthcare settings in India for:

1. Essential Hypertension Management: Treatment of adult patients with essential high blood pressure.

2. Step-Up Combination Therapy: Patients whose blood pressure is inadequately controlled on 20mg Olmesartan or 12.5mg Chlorthalidone monotherapy.

3. Cardiovascular & Renal Risk Management: Lowering elevated blood pressure to help reduce the risk of non-fatal stroke, myocardial infarction, and chronic kidney disease progression.

Dosage & Administration Guidelines

Always take OLMISTRUM CH 20 exactly as prescribed by your treating physician.

• Recommended Dose: Typically one tablet once daily.

• How to Take: Swallow the tablet whole with a glass of water. Do not break, crush, or chew the tablet.

• Timing: Can be taken with or without food. Taking your dose in the morning is recommended to prevent night-time trips to the bathroom due to the diuretic effect.

• Missed Dose: If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed tablet and resume your regular schedule. Do not double the dose.

Safety Profile, Side Effects & Precautions

OLMISTRUM CH 20 is generally well tolerated under medical supervision.

Common Side Effects

• Mild dizziness or lightheadedness when standing up quickly

• Increased frequency of urination during the initial weeks of treatment

• Mild fatigue or headache

• Transient electrolyte shifts (such as minor variations in serum potassium, sodium, or uric acid levels)

Key Contraindications & Warnings

• Pregnancy Warning: Strictly contraindicated during pregnancy. Drugs that act on the renin-angiotensin system (like Olmesartan) can cause severe fetal harm or toxicity when used during the second and third trimesters.

• Lactation: Consult your doctor before taking this medication while breastfeeding.

• Kidney & Liver Function: Requires cautious dosing and monitoring in patients with severe hepatic or renal impairment or biliary obstruction.

• Electrolyte Monitoring: Periodic blood tests to check serum potassium, sodium, uric acid, and creatinine levels are recommended during long-term therapy.

Quality Control & Manufacturing Standards

OLMISTRUM CH 20 is produced by Steris Healthcare Pvt. Ltd. in WHO-GMP-certified manufacturing facilities in India. Each 10-tablet strip uses moisture-resistant blister packaging to preserve drug stability, potency, and safety throughout its shelf life.

Frequently Asked Questions 

Where can I buy Olmesartan and Chlorthalidone online?

Olmesartan and Chlorthalidone can be purchased online through authorized pharmacies and pharmaceutical suppliers, subject to applicable prescription requirements. Always verify the product strength, manufacturer, and expiry date before purchasing.

What is the price of Olmesartan and Chlorthalidone?

The price depends on the specific strength, brand, pack size, and manufacturer. For the latest price, check the product listing or contact the authorized pharmaceutical supplier.

Can I order Olmesartan and Chlorthalidone online?

Yes, Olmesartan and Chlorthalidone may be ordered online through legitimate pharmaceutical platforms. A valid prescription may be required, so follow the seller's prescription and dispensing requirements.

Is Olmesartan and Chlorthalidone available from Steris Healthcare?

Availability depends on the specific product strength and current stock. You can contact Steris Healthcare to confirm availability, pack size, pricing, and ordering details.

What is Olmesartan and Chlorthalidone used for?

Olmesartan and Chlorthalidone are used together to help control high blood pressure (hypertension). Olmesartan helps relax blood vessels by blocking the action of angiotensin II, while Chlorthalidone is a diuretic that helps the body remove excess sodium and water.

What is the composition of Olmesartan and Chlorthalidone?

The combination contains Olmesartan Medoxomil and Chlorthalidone. The exact amount of each ingredient depends on the particular formulation. Common formulations may contain Olmesartan 20 mg with Chlorthalidone 12.5 mg, but the product label should always be checked for the exact composition.

Is a prescription required for Olmesartan and Chlorthalidone?

Yes. Olmesartan and Chlorthalidone is a prescription medicine and should be used under the guidance of a qualified healthcare professional. Do not start, stop, or change the dosage without medical advice.

How should Olmesartan and Chlorthalidone be taken?

Take Olmesartan and Chlorthalidone exactly as prescribed by your doctor. It is generally taken orally, preferably at the recommended time each day. Because Chlorthalidone can increase urination, your doctor may advise taking it at a suitable time during the day.

What should I know before buying Olmesartan and Chlorthalidone?

Before buying, verify the product name, strength, composition, manufacturer, pack size, expiry date, and authenticity. Tell your healthcare professional about other medicines you take and any medical conditions. Purchase prescription medicines only from legitimate sources.

How can I order Olmesartan and Chlorthalidone online?

To order online, select the required Olmesartan and Chlorthalidone formulation from an authorized pharmaceutical supplier, verify the strength and pack size, complete any prescription requirements, and provide the required delivery details. For Steris Healthcare products, contact the company to confirm current availability and ordering information.

Order OLMISTRUM CH 20 Online in India

Ordering OLMISTRUM CH 20 (Olmesartan 20mg + Chlorthalidone 12.5mg) online through verified pharmaceutical suppliers ensures reliable delivery of genuine medications across India.

• Guaranteed Product Authenticity: Direct distribution from Steris Healthcare Pvt. Ltd. guarantees authentic products with clear batch details and expiration dates.

• Simple Online Ordering: Upload a valid doctor's prescription to complete your order safely.