PIOSTERIS 7.5

PIOSTERIS 7.5 is an oral antidiabetic medication containing pioglitazone 7.5 mg, prescribed to help manage blood glucose levels in adults with type 2 diabetes mellitus. It belongs to the thiazolidinedione (TZD) class of drugs and works by improving the body’s sensitivity to insulin. As part of a comprehensive diabetes management plan—including diet and exercise—PIOSTERIS 7.5 helps maintain better glycemic control and reduce the risk of diabetes-related complications.

What is PIOSTERIS 7.5 (Pioglitazone 7.5 mg Tablet)?

PIOSTERIS 7.5 is a pioglitazone tablet containing pioglitazone 7.5 mg, designed for the treatment of type 2 diabetes. It does not increase insulin secretion but works by reducing insulin resistance.

Pioglitazone Mechanism of Action:

Pioglitazone activates peroxisome proliferator-activated receptor gamma (PPAR-γ) in fat cells, muscle, and the liver. This leads to:

• Improved insulin sensitivity

• Decreased glucose production by the liver

• Enhanced glucose uptake by peripheral tissues

This mechanism helps lower blood glucose without causing hypoglycemia when used alone.

Uses of Pioglitazone 7.5 mg

PIOSTERIS 7.5 is used for:

• Type 2 Diabetes Mellitus: To improve blood sugar control when lifestyle changes or other medications are insufficient.

• Combination Therapy: Can be used with metformin, sulfonylureas, or insulin when dual therapy is needed.

• Insulin Sensitization: Beneficial in patients with insulin resistance or metabolic syndrome.

This dose is particularly suitable for patients who require a lower starting dose due to tolerability concerns or to minimize side effects.

Side Effects of Pioglitazone 7.5 mg

Like any medication, pioglitazone 7.5 mg may cause side effects. While many are mild, some may be serious.

Common side effects:

• Weight gain

• Fluid retention or swelling (especially in the ankles)

• Muscle pain or back pain

• Headache

• Mild upper respiratory infections

Serious side effects:

• Heart failure – due to fluid retention

• Bladder cancer (rare, with long-term use)

• Bone fractures (more common in women)

• Macular edema (vision disturbances)

• Liver dysfunction

Report any signs of shortness of breath, rapid weight gain, unusual fatigue, or yellowing of the skin or eyes to your healthcare provider.

Precautions Before Using Pioglitazone 7.5 mg

Before starting PIOSTERIS 7.5, inform your healthcare provider if you:

• Have a history of heart failure or cardiovascular disease

• Have liver problems or elevated liver enzymes

• Have or have had bladder cancer

• Are pregnant, trying to conceive, or breastfeeding

• Consume alcohol frequently

• Are at increased risk of osteoporosis or fractures

Regular monitoring of liver function and heart health is recommended during treatment.

Drug Interactions – What Drugs Interact with Pioglitazone 7.5 mg?

Pioglitazone may interact with other medications, altering its effectiveness or increasing side effects:

• Insulin or sulfonylureas – May increase the risk of hypoglycemia and fluid retention

• Gemfibrozil – Increases pioglitazone concentration and effects

• Rifampicin – Reduces pioglitazone effectiveness

• Oral contraceptives – Pioglitazone may reduce their effectiveness

• Diuretics – Increase risk of fluid retention and swelling

Always share your full medication list with your healthcare provider before starting PIOSTERIS 7.5.

Conclusion:

PIOSTERIS 7.5 (pioglitazone 7.5 mg tablet) offers a lower-dose, effective option for improving insulin sensitivity in adults with type 2 diabetes. With its unique pioglitazone mechanism of action, it supports better blood sugar control while being well-tolerated by many patients. Regular follow-up and monitoring are key to maximizing benefits and minimizing potential pioglitazone side effects.