OLMISTRUM TRIO 20

Hypertension, commonly known as high blood pressure, is one of the leading causes of cardiovascular disease in India. Sedentary lifestyles, high salt intake, stress, obesity, and genetic factors have significantly increased the number of people requiring long-term blood pressure management. Uncontrolled hypertension can lead to serious complications such as heart attack, stroke, kidney failure, and vision problems.

OLMISTRUM TRIO 20 is a comprehensive triple-drug antihypertensive formulation containing Olmesartan Medoxomil 20 mg, Cilnidipine 10 mg, and Chlorthalidone 12.5 mg. This powerful combination is designed to provide effective, sustained, and well-balanced blood pressure control in patients whose hypertension is not adequately controlled with single or dual therapy.

Composition of OLMISTRUM TRIO 20

Each film-coated tablet contains:

• Olmesartan Medoxomil – 20 mg

• Cilnidipine – 10 mg

• Chlorthalidone – 12.5 mg

Excipients: q.s.

This triple combination targets different mechanisms responsible for high blood pressure, ensuring optimal therapeutic outcomes.

Understanding Hypertension and the Need for Combination Therapy

Hypertension is often a multifactorial condition, meaning it occurs due to multiple physiological mechanisms. In many patients, a single antihypertensive agent may not be sufficient to achieve target blood pressure levels.

Combination therapy:

• Improves blood pressure control

• Reduces cardiovascular risk

• Minimises dose-related side effects

• Enhances patient compliance

OLMISTRUM TRIO 20 is especially beneficial for patients with moderate to severe hypertension or those at high cardiovascular risk.

How Does OLMISTRUM TRIO 20 Work?

1. Olmesartan Medoxomil

Olmesartan is an angiotensin II receptor blocker (ARB). It relaxes blood vessels by blocking the action of angiotensin II, a hormone responsible for blood vessel constriction. This leads to:

• Reduced vascular resistance

• Lower blood pressure

• Protection of the heart and kidneys

2. Cilnidipine

Cilnidipine is a dual L-type and N-type calcium channel blocker. It:

• Relaxes arterial blood vessels

• Reduces sympathetic nerve activity

• Minimises reflex tachycardia

• Offers additional renal and cardiovascular protection

3. Chlorthalidone

Chlorthalidone is a thiazide-like diuretic that helps:

• Eliminate excess salt and water from the body

• Reduce blood volume

• Enhance the antihypertensive effect of other drugs

Together, these agents provide 24-hour blood pressure control with improved tolerability.

Uses of OLMISTRUM TRIO 20

OLMISTRUM TRIO 20 is prescribed for:

• Management of essential hypertension

• Patients with uncontrolled blood pressure on dual therapy

• High-risk hypertensive patients with diabetes or kidney disease

• Prevention of cardiovascular complications related to hypertension

Benefits of OLMISTRUM TRIO 20

• Effective triple-action blood pressure control

• Reduces risk of heart attack and stroke

• Provides renal and cardiovascular protection

• Once-daily dosing for better compliance

• Minimises blood pressure fluctuations

• Suitable for long-term hypertension management

Dosage and Administration

Dosage should always be followed as prescribed by a healthcare professional.

General Dosage Guidelines

• One tablet once daily

• Can be taken with or without food

• Swallow whole with water

• Preferably taken at the same time every day

Dose adjustment may be required based on patient response and clinical condition.

Side Effects of OLMISTRUM TRIO 20

Most patients tolerate OLMISTRUM TRIO 20 well. However, some side effects may occur.

Common Side Effects

• Dizziness

• Headache

• Fatigue

• Increased urination

• Mild ankle swelling

Less Common Side Effects

• Low blood pressure

• Muscle cramps

• Electrolyte imbalance

• Dry mouth

Rare Side Effects

• Kidney function changes

• Allergic reactions

• Severe hypotension

Medical advice should be sought if side effects persist or worsen.

Precautions and Warnings

Before taking OLMISTRUM TRIO 20, inform your doctor if you have:

• Kidney or liver disease

• Electrolyte imbalance

• Heart conditions

• Dehydration

Additional precautions:

• Not recommended during pregnancy and breastfeeding

• Regular monitoring of blood pressure, kidney function, and electrolytes is advised

• Avoid excessive alcohol intake

• Maintain adequate hydration

Drug Interactions

OLMISTRUM TRIO 20 may interact with:

• Other antihypertensive medications

• NSAIDs

• Potassium supplements

• Lithium

• Certain diabetes medicines

Always inform your doctor about all medicines you are taking.

Lifestyle Modifications Along with OLMISTRUM TRIO 20

For optimal blood pressure control, medication should be combined with:

• Low-salt, heart-healthy diet

• Regular physical activity

• Weight management

• Stress reduction

• Avoidance of smoking and excess alcohol

Why Choose OLMISTRUM TRIO 20 from Steris Healthcare?

Steris Healthcare Pvt. Ltd. is known for its commitment to quality, safety, and innovation. OLMISTRUM TRIO 20 is manufactured under strict quality standards to ensure:

• Consistent efficacy

• High safety profile

• Reliable patient outcomes

• Trust among healthcare professionals across India

Storage Instructions

• Store below 25°C

• Protect from light and moisture

• Keep out of reach of children

• Do not use after the expiry date

Conclusion

OLMISTRUM TRIO 20 is a scientifically designed triple-drug combination that offers comprehensive blood pressure control for patients with moderate to severe hypertension. By targeting multiple pathways involved in blood pressure regulation, it helps reduce cardiovascular risks and improves overall quality of life. Backed by the quality standards of Steris Healthcare Pvt. Ltd., OLMISTRUM TRIO 20 stands as a dependable choice for effective and long-term hypertension management.

Frequently Asked Questions (FAQs)

Q1. Who should take OLMISTRUM TRIO 20?
It is prescribed for patients with hypertension not adequately controlled with one or two medications.

Q2. Can OLMISTRUM TRIO 20 be taken long term?
Yes, it is suitable for long-term use under medical supervision.

Q3. Does it cause frequent urination?
Yes, due to the presence of chlorthalidone, increased urination may occur initially.

Q4. Can elderly patients take this medicine?
Yes, with careful monitoring and dose adjustment if needed.