OLMISTRUM MT 25

OLMISTRUM MT 25 (Olmesartan Medoxomil 20 mg & Metoprolol Succinate 25 mg) is a dual-action prescription medication for targeted hypertension management.

What is OLMISTRUM MT 25?

OLMISTRUM MT 25 is a cardiovascular drug formulated by Steris Healthcare Pvt. Ltd. for treating essential hypertension (high blood pressure) when single-agent therapy is insufficient.

It merges two proven antihypertensive active ingredients in a single daily tablet:

1. Olmesartan Medoxomil (20 mg): An Angiotensin II Receptor Blocker (ARB).

2. Metoprolol Succinate (25 mg): A cardioselective Beta-1 adrenergic blocker delivered in an Extended Release (ER) matrix.

This dual combination provides round-the-clock 24-hour arterial pressure control, preventing hypertension-induced cardiovascular events.

Mechanism of Action (How It Works)

High blood pressure often stems from multiple physiological pathways. OLMISTRUM MT 25 addresses two primary mechanisms simultaneously:

• The Role of Olmesartan Medoxomil (20 mg):

  Olmesartan targets the Renin-Angiotensin-Aldosterone System (RAAS). It selectively blocks angiotensin II from binding to $AT_1$ receptors in vascular smooth muscle cells. This action prevents vessel constriction, relaxes peripheral arterial walls, and reduces total peripheral resistance (TPR) to promote smooth blood flow.

• The Role of Metoprolol Succinate (25 mg):

  Metoprolol selectively blocks Beta-1 receptors located in heart tissue. By blocking sympathetic nervous system stimulation, it reduces the resting heart rate, decreases myocardial contractility, and lowers cardiac output. The succinate salt provides steady sustained release throughout the day, mitigating blood pressure spikes.

Primary Uses & Therapeutic Indications

Physicians in India prescribe OLMISTRUM MT 25 for several clinical indications:

• Essential Hypertension: Managed when olmesartan 20 mg or metoprolol 25 mg monotherapy fails to achieve goal blood pressure.

• Cardiovascular Risk Reduction: Controls sustained hypertension to reduce the risk of secondary cardiac events, such as myocardial infarction (heart attack) and stroke.

• Renal Protection in Hypertensives: Helps delay the progression of hypertension-induced renal damage.

• Ischemic Heart Disease Management: Metoprolol reduces myocardial oxygen demand, helping manage concurrent stable angina or post-infarction care under specialist supervision.

Key Clinical Benefits

1. Dual-Mechanistic Control: Combines vascular dilation (olmesartan) with heart rate modulation (metoprolol).

2. 24-Hour Coverage: The extended-release metoprolol component provides sustained plasma levels, guarding against early-morning blood pressure surges.

3. Improved Compliance: Combining two active ingredients into a single daily tablet reduces pill burden.

4. Cardioprotective Properties: Reduces cardiac workload and protects arterial health long-term.

Standard Dosage & Administration Guidelines

• General Dosage: Take one tablet daily, or strictly as prescribed by your treating physician.

• Timing: Take your dose at the same time every day to maintain constant therapeutic blood levels.

• Method of Intake: Swallow the tablet whole with a glass of water. Do not crush, chew, or break extended-release tablets.

• Relation to Meals: Take with or shortly after a meal to optimize absorption and minimize stomach upset.

• Missed Dose: Take the missed tablet as soon as you remember. If your next scheduled dose is near, skip the missed tablet. Never take a double dose to make up for a missed one.

Side Effects & Precautionary Profile

While generally well-tolerated, OLMISTRUM MT 25 may cause side effects in some patients as their bodies adapt.

Common Side Effects

• Dizziness or lightheadedness (especially when standing up)

• Fatigue or lethargy

• Bradycardia (slight slowing of heart rate)

• Mild gastrointestinal discomfort, nausea, or diarrhea

• Cold hands or feet

Critical Safety Warnings & Contraindications

• Pregnancy Warning: Contraindicated in pregnant women. ARBs like olmesartan can cause severe fetal harm or death when administered during the second and third trimesters. Discontinue immediately if pregnancy is detected.

• Lactation: Avoid unless explicitly advised by a physician.

• Asthma & COPD: Use metoprolol with caution in patients with reactive airway diseases, as beta-blockers can trigger bronchospasms.

• Severe Bradycardia / Heart Block: Do not use if you have second- or third-degree heart block, cardiogenic shock, or severe sick sinus syndrome without a pacemaker.

• Kidney & Liver Impairment: Requires close monitoring of serum creatinine, blood urea, and liver enzymes.

• Abrupt Discontinuation: Do not stop taking OLMISTRUM MT 25 abruptly. Sudden withdrawal of beta-blockers can cause severe rebound hypertension, angina spikes, or heart attack. Taper the dosage under medical supervision.

Storage & Handling

• Store below 30°C in a dry place.

• Protect from direct sunlight, light, and moisture.

• Keep out of reach of children and pets.

• Retain tablets in their original blister packaging until use.

Order OLMISTRUM MT 25 Online in India

You can purchase OLMISTRUM MT 25 (Pack of 10 Tablets) by Steris Healthcare Pvt. Ltd. online with door-step delivery across India.

• Genuine Quality: Sourced directly from verified pharmaceutical distributors.

• Secure Packaging: Temperature-safe, discrete, and damage-resistant packaging.

• Fast India-Wide Delivery: Available across metro cities and pan-India pin codes.

Frequently Asked Questions 

Where can I buy Olmesartan 20 mg and Metoprolol 25 mg online?

Olmesartan 20 mg and Metoprolol 25 mg can be purchased online through authorized pharmacies and pharmaceutical suppliers, subject to applicable prescription requirements. Always verify the strength, manufacturer, pack size, and expiry date before purchasing.

What is the price of Olmesartan 20 mg and Metoprolol 25 mg?

The price may vary depending on the brand, manufacturer, pack size, and seller. For the latest price, check the product listing or contact the authorized pharmaceutical supplier for current pricing.

Can I order Olmesartan 20 mg and Metoprolol 25 mg online?

Yes, this combination can be ordered online through legitimate pharmaceutical platforms where available. A valid prescription may be required, so follow the applicable prescription and dispensing requirements.

Is Olmesartan 20 mg and Metoprolol 25 mg available from Steris Healthcare?

Availability depends on the current product range and stock. You can contact Steris Healthcare to confirm the availability, strength, pack size, pricing, and ordering details.

What is Olmesartan 20 mg and Metoprolol 25 mg used for?

Olmesartan 20 mg and Metoprolol 25 mg is used to help control high blood pressure (hypertension). Olmesartan is an angiotensin II receptor blocker (ARB), while Metoprolol is a beta-blocker. The combination works through different mechanisms to help lower blood pressure.

What is the composition of Olmesartan 20 mg and Metoprolol 25 mg?

The composition contains Olmesartan Medoxomil 20 mg and Metoprolol 25 mg. The exact formulation of Metoprolol, such as its salt or release form, should be confirmed from the specific product label.

Is a prescription required for Olmesartan 20 mg and Metoprolol 25 mg?

Yes. Olmesartan 20 mg and Metoprolol 25 mg is a prescription medicine. It should be taken only under the guidance of a qualified healthcare professional. Do not start, stop, or change the dosage without medical advice.

How should Olmesartan 20 mg and Metoprolol 25 mg be taken?

Take Olmesartan 20 mg and Metoprolol 25 mg exactly as prescribed by your doctor. Take it orally at the recommended time and follow the prescribed schedule consistently. Do not stop Metoprolol suddenly unless your doctor advises you to do so.

What should I know before buying Olmesartan 20 mg and Metoprolol 25 mg?

Before buying, check the medicine name, strength, exact composition, manufacturer, pack size, expiry date, and authenticity. Tell your healthcare professional about other medicines you take and any existing medical conditions, particularly heart-related conditions or problems affecting blood pressure.

How can I order Olmesartan 20 mg and Metoprolol 25 mg online?

To order online, select the required Olmesartan 20 mg and Metoprolol 25 mg product from an authorized pharmaceutical supplier, verify the strength and pack size, complete any prescription requirements, and provide the required delivery details. For Steris Healthcare products, contact the company to confirm current availability, pricing, and ordering options.