OLMISTRUM MT 20/50

OLMISTRUM MT 20/50 (Olmesartan Medoxomil 20 mg & Metoprolol Succinate 50 mg) is a dual-action prescription combination engineered for targeted hypertension management and cardiovascular protection.

Product Information

Buy OLMISTRUM MT 20/50 Online in India

Order OLMISTRUM MT 20/50 (Pack of 10 Tablets) by Steris Healthcare Pvt. Ltd. through licensed Indian online pharmacies with fast doorstep delivery.

• 100% Genuine Healthcare Products: Direct supply from verified pharmaceutical distributors.

• Pan-India Delivery: Express shipping available across major metro cities, tier-2 towns, and regional pincodes in India.

• Secure Prescription Upload: Easy verification process ensures full compliance with Indian medical regulations.

• Discreet & Temperature-Safe Packaging: Protects active drug stability during transit.

What is OLMISTRUM MT 20/50?

OLMISTRUM MT 20/50 is a fixed-dose combination medication formulated by Steris Healthcare Pvt. Ltd. to manage high blood pressure (essential hypertension). It is specifically indicated when single-agent therapy fails to achieve optimal blood pressure targets.

The tablet combines two synergistic active ingredients:

1. Olmesartan Medoxomil (20 mg): A potent, long-acting Angiotensin II Receptor Blocker (ARB).

2. Metoprolol Succinate (50 mg): A cardioselective Beta-1 adrenergic receptor blocker delivered via a sustained-release matrix.

By combining vascular dilation with heart rate reduction, OLMISTRUM MT 20/50 delivers comprehensive 24-hour arterial pressure control, reducing the workload on the heart and helping prevent hypertension-related organ damage.

How OLMISTRUM MT 20/50 Works (Mechanism of Action)

Sustained high blood pressure involves multiple physiological pathways, including vascular constriction and sympathetic nervous system overactivity. OLMISTRUM MT 20/50 addresses both mechanisms simultaneously:

1. Olmesartan Medoxomil (20 mg) – Vascular Relaxation

Olmesartan targets the Renin-Angiotensin-Aldosterone System (RAAS). It selectively blocks angiotensin II from binding to the $AT_1$ receptor in vascular smooth muscle. Blocking this signal prevents blood vessel constriction, causing the arterial walls to relax, lowering peripheral vascular resistance, and promoting smoother circulation.

2. Metoprolol Succinate (50 mg) – Cardiac Modulation

Metoprolol selectively blocks Beta-1 receptors in heart muscle. By inhibiting sympathetic nervous system stimulation, it reduces resting heart rate, decreases myocardial contractility, and lowers cardiac output. The extended-release succinate salt provides steady drug release, preventing morning blood pressure spikes and maintaining consistent cardiovascular protection.

Key Therapeutic Indications

Doctors in India prescribe OLMISTRUM MT 20/50 for several key cardiovascular conditions:

• Uncontrolled Essential Hypertension: For patients whose blood pressure remains above target on single-agent ARB or beta-blocker therapy.

• Prevention of Cardiovascular Events: Long-term blood pressure control reduces the risk of stroke, heart attack (myocardial infarction), and cardiovascular mortality.

• Management of Co-existing Angina & Hypertension: Helps patients with both elevated blood pressure and chronic stable angina by reducing cardiac oxygen consumption.

• Post-Myocardial Infarction Management: Aids in long-term cardiac protection following a heart attack under expert medical supervision.

Clinical Advantages of Combination Therapy

• Dual Mechanism Synergy: Combines arterial dilation with cardiac output regulation for balanced control.

• 24-Hour Coverage: Extended-release formulation maintains smooth therapeutic levels throughout the day and night.

• Improved Patient Compliance: Replacing two separate pills with a single daily tablet simplifies treatment schedules.

• Organ Protection: Helps shield vulnerable microvascular beds in the kidneys, brain, and retina from sustained high pressure.

Dosage & Administration Guidelines

• General Schedule: Take one tablet daily, or strictly as directed by your physician.

• Administration: Swallow the tablet whole with water. Do not crush, chew, or break extended-release tablets, as this destroys the controlled-release mechanism.

• Timing: Take your dose at the same time every day (preferably in the morning or after meals) to maintain steady blood levels.

• Food Effect: Can be taken with or shortly after a meal to reduce stomach discomfort.

• Missed Dose: Take the missed tablet as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose. Do not double up doses.

Side Effects & Precautions

While OLMISTRUM MT 20/50 is generally well-tolerated, some patients may experience mild to moderate side effects as their body adjusts.

Common Side Effects

• Dizziness or lightheadedness when standing up (orthostatic hypotension)

• Slow heart rate (bradycardia)

• Fatigue or general tiredness

• Cold hands or feet

• Mild gastrointestinal upset (nausea, mild diarrhea, or indigestion)

Warnings & Safety Precautions

• Pregnancy Warning: Contraindicated during pregnancy. Angiotensin receptor blockers like olmesartan can cause serious fetal injury or death, particularly during the second and third trimesters. Discontinue immediately if pregnancy is confirmed.

• Lactation: Use with caution during breastfeeding and only under explicit medical advice.

• Asthma & Respiratory Conditions: Use with caution in patients with reactive airway disease or chronic obstructive pulmonary disease (COPD), as beta-blockers can cause airway narrowing.

• Heart Block & Severe Bradycardia: Do not use in patients with second- or third-degree heart block, severe sinus node dysfunction, or cardiogenic shock without a pacemaker.

• Renal & Hepatic Impairment: Requires periodic monitoring of serum creatinine, blood urea nitrogen, and liver function markers.

• Abrupt Discontinuation: Never stop taking OLMISTRUM MT 20/50 abruptly. Sudden cessation of beta-blockers can cause rebound hypertension, severe angina, or acute cardiac events. Always taper down dosage gradually under medical guidance.

Storage Instructions

• Store at temperatures below 30°C in a cool, dry place.

• Keep protected from direct sunlight, excess heat, and moisture.

• Keep out of reach of children and domestic pets.

• Keep tablets in their original blister pack until immediate use.

Frequently Asked Questions 

Where can I buy Olmesartan 20 mg and Metoprolol 50 mg online?

Olmesartan 20 mg and Metoprolol 50 mg can be purchased online through authorized pharmacies and pharmaceutical suppliers, subject to applicable prescription requirements. Always verify the product strength, manufacturer, pack size, and expiry date before purchasing.

What is the price of Olmesartan 20 mg and Metoprolol 50 mg?

The price may vary depending on the brand, manufacturer, pack size, and seller. For the latest price, check the product listing or contact the authorized pharmaceutical supplier for current pricing.

Can I order Olmesartan 20 mg and Metoprolol 50 mg online?

Yes, this combination can be ordered online through legitimate pharmaceutical platforms where available. A valid prescription may be required, so follow the applicable prescription and dispensing requirements.

Is Olmesartan 20 mg and Metoprolol 50 mg available from Steris Healthcare?

Availability depends on the current product range and stock. You can contact Steris Healthcare to confirm the availability, strength, pack size, pricing, and ordering details.

What is Olmesartan 20 mg and Metoprolol 50 mg used for?

Olmesartan 20 mg and Metoprolol 50 mg is used to help manage high blood pressure (hypertension). Olmesartan is an angiotensin II receptor blocker (ARB), while Metoprolol is a beta-blocker. They work through different mechanisms to help reduce blood pressure.

What is the composition of Olmesartan 20 mg and Metoprolol 50 mg?

The composition contains Olmesartan Medoxomil 20 mg and Metoprolol 50 mg. The specific form of Metoprolol, such as its salt or extended-release formulation, should be confirmed on the product packaging.

Is a prescription required for Olmesartan 20 mg and Metoprolol 50 mg?

Yes. Olmesartan 20 mg and Metoprolol 50 mg is a prescription medicine and should be used under the supervision of a qualified healthcare professional. Do not change the prescribed dose without medical advice.

How should Olmesartan 20 mg and Metoprolol 50 mg be taken?

Take Olmesartan 20 mg and Metoprolol 50 mg exactly as prescribed by your doctor. Take the medicine orally at the recommended time and follow the prescribed schedule consistently. Do not stop Metoprolol abruptly without consulting your doctor.

What should I know before buying Olmesartan 20 mg and Metoprolol 50 mg?

Before buying, check the medicine name, strength, exact composition, manufacturer, pack size, expiry date, and authenticity. Inform your doctor about other medicines you take and any existing medical conditions, particularly heart or blood-pressure-related conditions.

How can I order Olmesartan 20 mg and Metoprolol 50 mg online?

To order online, select the required Olmesartan 20 mg and Metoprolol 50 mg product from an authorized pharmaceutical supplier, verify the strength and pack size, complete any prescription requirements, and provide the required delivery details. For Steris Healthcare products, contact the company to confirm current availability, pricing, and ordering options.