Nintedanib Soft Gelatin Capsules | NINTEPRIDE 150

NINTEPRIDE 150 is a prescription medication formulated with Nintedanib 150mg, designed primarily for the treatment of idiopathic pulmonary fibrosis (IPF), systemic sclerosis-associated interstitial lung disease (SSc-ILD), and other chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype. It helps in slowing down the decline of lung function and is a valuable therapy in the management of fibrotic lung disorders.

Key Ingredient:

Nintedanib (150mg)
Nintedanib is a tyrosine kinase inhibitor (TKI) that targets multiple growth factor receptors involved in the progression of lung fibrosis. It is an anti-fibrotic agent that interrupts signaling pathways that lead to scarring in lung tissue.

Key Benefits:

• Helps slow the progression of lung fibrosis in IPF and other chronic fibrosing ILDs.

• Supports better lung function over time in patients with progressive interstitial lung diseases.

• May reduce the rate of decline in forced vital capacity (FVC), a key measure of lung function.

• Offers a targeted therapeutic approach by inhibiting growth factor receptors involved in fibrosis.

• Improves quality of life by stabilizing respiratory symptoms in chronic pulmonary conditions.

How Does It Work?

NINTEPRIDE 150 works by inhibiting several receptor tyrosine kinases (RTKs), including platelet-derived growth factor receptor (PDGFR), fibroblast growth factor receptor (FGFR), and vascular endothelial growth factor receptor (VEGFR). These receptors play a major role in the processes of fibrosis, including fibroblast proliferation and migration. By blocking these pathways, Nintedanib helps reduce the formation of scar tissue in the lungs, thus slowing disease progression in fibrotic lung conditions.

Directions for Use:

• NINTEPRIDE 150 should be taken orally with food to improve absorption and minimize gastrointestinal side effects.

• The usual dosage is one capsule (150mg) twice daily, approximately 12 hours apart.

• Do not crush, chew, or open the capsules; swallow them whole with water.

• Follow the dosage and administration schedule as prescribed by your healthcare provider.

• Do not adjust the dose or discontinue the medication without consulting your doctor.

Side Effects:

• Diarrhea is the most common side effect and may require dose adjustment or treatment.

• Nausea and vomiting, especially when taken on an empty stomach.

• Elevated liver enzymes, which may need regular monitoring.

• Loss of appetite and weight loss may occur with prolonged use.

• Headache, fatigue, and abdominal pain are also reported in some patients.

• In rare cases, it may cause bleeding complications or gastrointestinal perforation.

• Notify your healthcare provider immediately if you experience severe liver issues, persistent abdominal pain, or unusual bleeding.

Frequently Asked Questions

What are Nintedanib Soft Gelatin Capsules used for?

Nintedanib Soft Gelatin Capsules are prescribed to help slow the progression of certain fibrotic lung diseases, including idiopathic pulmonary fibrosis (IPF), progressive fibrosing interstitial lung diseases, and systemic sclerosis-associated interstitial lung disease, depending on local regulatory approval.

How do Nintedanib Soft Gelatin Capsules work?

They work by blocking multiple tyrosine kinase receptors involved in fibrosis, helping reduce abnormal scar tissue formation and slowing the decline in lung function.

Are Nintedanib Soft Gelatin Capsules a cure for pulmonary fibrosis?

No. Nintedanib is not a cure, but it helps slow disease progression and preserve lung function when taken as prescribed.

How should I take Nintedanib Soft Gelatin Capsules?

Take the capsules exactly as prescribed by your healthcare provider, usually with food, and swallow them whole without crushing, chewing, or opening them.

Can I take Nintedanib Soft Gelatin Capsules on an empty stomach?

It is generally recommended to take the capsules with food to improve tolerability and reduce the risk of gastrointestinal side effects.

What are the most common side effects of Nintedanib?

Common side effects include diarrhea, nausea, vomiting, abdominal pain, decreased appetite, weight loss, fatigue, and elevated liver enzyme levels.

Who should not take Nintedanib Soft Gelatin Capsules?

People with certain liver conditions, those who are allergic to Nintedanib or any capsule ingredient, and pregnant individuals should discuss treatment suitability with their healthcare provider before starting therapy.

Can Nintedanib Soft Gelatin Capsules interact with other medications?

Yes. They may interact with blood thinners, certain antibiotics, antifungal medicines, and other drugs. Always inform your healthcare provider about all medicines and supplements you are taking.

Do I need regular monitoring while taking Nintedanib?

Yes. Routine monitoring, including liver function tests and regular clinical evaluations, is important throughout treatment.

Is a prescription required to buy Nintedanib Soft Gelatin Capsules?

Yes. Nintedanib Soft Gelatin Capsules are prescription-only medicines and should only be purchased with a valid prescription from a licensed pharmacy or authorized pharmaceutical supplier.

Can I buy Nintedanib Soft Gelatin Capsules online?

You can purchase them online only through licensed and authorized pharmacies or pharmaceutical suppliers that comply with local regulations and require a valid prescription.

How should Nintedanib Soft Gelatin Capsules be stored?

Store the capsules at room temperature in their original packaging, protected from moisture, heat, and direct sunlight, and keep them out of reach of children.

What should I do if I miss a dose?

If you miss a dose, skip it and take the next dose at the scheduled time. Do not take a double dose to make up for the missed one.

How long will I need to take Nintedanib Soft Gelatin Capsules?

Treatment duration varies depending on your medical condition and response to therapy. Your healthcare provider will determine how long you should continue taking the medication based on regular follow-up assessments.

Product Information

Brand Name: NINTEPRIDE 150 (STERIS HEALTHCARE PVT LTD)

Composition Name: Nintedanib Soft Gelatin capsules 150 mg

Pack Size: Strip of 10 CAPSULES 

Marketed By: Steris Healthcare Pvt Ltd

Regulatory Standard: WHO-GMP Certified

Schedule: Valid Prescription Required (Prescription Only)

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