Nintedanib Soft Gelatin Capsules | NINTEPRIDE150

Nintepride 15 contains Nintedanib 150mg in a soft gelatin capsule, manufactured by Steris Healthcare Pvt. Ltd. It is a prescription-only (Schedule H) triple angiokinase inhibitor primarily prescribed for Idiopathic Pulmonary Fibrosis (IPF), Progressive Fibrosing Interstitial Lung Disease (PF-ILD), and Systemic Sclerosis-Associated ILD (SSc-ILD), and — in combination with docetaxel — for certain types of advanced lung cancer. It works by blocking growth-factor receptor pathways (VEGFR, FGFR, PDGFR) that drive lung scarring and abnormal blood vessel growth. The standard adult dose is 150mg twice daily with food, though your pulmonologist or oncologist may adjust this based on liver function and tolerability. Nintepride 15 is sold in a pack of 10 capsules and requires a valid prescription. 

What Is Nintepride 15?

If you or a loved one has just been handed a diagnosis of pulmonary fibrosis, the flood of new medical terms can feel overwhelming. Nintepride 15 is one of the most important tools available today to help slow that condition down. It's a modern, targeted oral therapy — not a steroid, not a broad immunosuppressant — designed specifically to interrupt the biological signals that cause healthy lung tissue to scar over and stiffen.

Each Nintepride 15 soft gelatin capsule delivers 150mg of Nintedanib, manufactured under WHO-GMP and ISO-certified conditions by Steris Healthcare Pvt. Ltd. Because this molecule requires careful dosing, liver monitoring, and physician supervision, it is classified as a Schedule H prescription drug in India — you will need a valid prescription from a pulmonologist, rheumatologist, or oncologist to purchase it.

The friendly way to think about Nintepride 15: it doesn't reverse existing lung scarring, but robust clinical evidence shows it can meaningfully slow the rate of lung function decline, helping patients preserve breathing capacity and quality of life for longer.

Product Information

Brand Name: NINTEPRIDE 150 (STERIS HEALTHCARE PVT LTD)

Composition Name: Nintedanib Soft Gelatin capsules 150 mg

Pack Size: Strip of 10 CAPSULES 

Marketed By: Steris Healthcare Pvt Ltd

Regulatory Standard: WHO-GMP Certified

Schedule: Valid Prescription Required (Prescription Only)

Clinical Indications

Condition	How Nintepride 15 (Nintedanib) Helps
Idiopathic Pulmonary Fibrosis (IPF)	Slows the annual decline in forced vital capacity (FVC), the standard measure of lung function in IPF
Progressive Fibrosing Interstitial Lung Disease (PF-ILD)	Approved for chronic fibrosing ILDs with a progressive phenotype beyond IPF
Systemic Sclerosis-Associated ILD (SSc-ILD)	Slows lung function decline in patients whose scleroderma has progressed to lung involvement
Non-Small Cell Lung Cancer (NSCLC), adenocarcinoma	Used in combination with docetaxel as a second-line option after prior chemotherapy, under oncologist supervision

Mechanism of Action: How Nintepride 15 Works

Nintedanib is classified as a triple angiokinase inhibitor. In plain language, it blocks three families of receptors that fuel fibrosis and abnormal vascular growth:

• VEGFR (Vascular Endothelial Growth Factor Receptor) — involved in forming new, often leaky, blood vessels that feed scar tissue
• FGFR (Fibroblast Growth Factor Receptor) — drives fibroblast activity, the cells directly responsible for laying down scar collagen in the lungs
• PDGFR (Platelet-Derived Growth Factor Receptor) — promotes fibroblast proliferation and migration into lung tissue

Key Benefits of Nintepride 15

• Clinically shown to slow the yearly rate of lung function (FVC) decline in IPF and PF-ILD patients
• Oral capsule formulation — no infusions or hospital visits required for routine dosing
• Backed by large multinational Phase III trial data (INPULSIS and SENSCIS study programs) for its originator molecule
• Manufactured in WHO-GMP and ISO-certified facilities by Steris Healthcare for consistent capsule-to-capsule quality
• Available in a convenient 10-capsule pack size, suited to short-term trials of tolerability before longer-term refills
• Can be used alongside supportive therapies like pulmonary rehabilitation, oxygen therapy, and antifibrotic care plans

Dosage & Administration Guidelines

Standard adult dose: 150mg (one Nintepride 15 capsule) taken twice daily, approximately 12 hours apart, with food.

• Swallow the capsule whole with a full glass of water — do not chew, crush, or open it
• Taking it with a meal significantly reduces stomach upset and nausea
• If diarrhea, liver enzyme elevation, or other side effects occur, your doctor may temporarily interrupt treatment or step the dose down to 100mg twice daily
• Missed dose: skip it and resume your next scheduled dose — never double up
• Do not stop or restart Nintepride 15 without your doctor's guidance, as abrupt changes can affect disease monitoring

Side Effects

Common side effects (usually manageable):

• Diarrhea (the most frequently reported side effect)
• Nausea and vomiting
• Decreased appetite and mild weight loss
• Abdominal pain
• Headache
• Mildly elevated liver enzymes

Serious side effects (seek medical attention immediately):

• Signs of liver injury — yellowing of skin/eyes, dark urine, severe fatigue
• Unexplained abdominal pain suggestive of gastrointestinal perforation
• Unusual bleeding or bruising
• Chest pain, sudden weakness, or slurred speech (possible arterial clot)
• Swelling or pain in one leg (possible deep vein thrombosis)
• Poor wound healing after any planned surgery

Substitutes & Comparable Antifibrotic Options

Brand / Molecule	Class	Typical Use Case
Nintepride 15 (Nintedanib 150mg – Steris Healthcare)	Triple angiokinase inhibitor	IPF, PF-ILD, SSc-ILD, NSCLC (combination)
Ofev (Nintedanib, originator brand)	Triple angiokinase inhibitor	Same indications; higher-priced originator
Pirfenidone-based brands	Anti-fibrotic (different mechanism)	Alternative first-line option for IPF
Other domestic Nintedanib generics	Triple angiokinase inhibitor	Bioequivalent alternatives at varying price points

Precautions & Safety Information

• Liver monitoring is mandatory: Your doctor will check liver function tests (LFTs) before starting Nintepride 15 and periodically during treatment
• Not for use in pregnancy: Nintedanib can cause harm to a developing fetus; women of childbearing potential must use effective contraception during and for at least 3 months after treatment
• Avoid if breastfeeding, unless specifically advised otherwise by your doctor
• Surgical caution: Inform your surgeon if any surgery is planned — Nintepride 15 may need to be paused because of wound-healing and bleeding risk
• Use caution with blood thinners (anticoagulants/antiplatelets), as bleeding risk may be increased
• Cardiovascular history: Disclose any history of heart attack, stroke, or blood clots to your doctor before starting therapy
• Avoid in significant hepatic impairment unless your doctor determines the benefit outweighs the risk
• Keep all follow-up appointments — this medicine requires ongoing monitoring, not a one-time prescription

Why Choose Nintepride 15 from Steris Healthcare?

Steris Healthcare Pvt. Ltd. is a WHO-GMP and ISO-certified pharmaceutical manufacturer, which means Nintepride 15 is produced under internationally benchmarked quality-control standards — consistent capsule potency, validated stability, and traceable batch quality. For a long-term therapy like antifibrotic treatment, where consistency between refills genuinely matters for disease monitoring, sourcing from a certified manufacturer is a meaningful reassurance for patients and caregivers alike.

If you're ready to move forward, the fastest next step is to check current, verified pricing before you buy — pharmaceutical pricing for specialty respiratory medicines like nintedanib fluctuates with pack size, city, and pharmacy margins, so live price-checking is more reliable than a number frozen on a webpage.

Frequently Asked Questions 

1. What is nintedanib 150 mg used for?

Nintedanib 150mg is used to treat Idiopathic Pulmonary Fibrosis (IPF), progressive fibrosing interstitial lung disease (PF-ILD), and systemic sclerosis-associated interstitial lung disease (SSc-ILD). It's also used in combination with docetaxel chemotherapy for certain advanced lung cancers. It works by blocking growth-factor pathways that drive lung scarring.

2. What is NINtenA 150mg Soft Gelatin capsule used for?

NINtenA is a different brand name containing the same active ingredient, Nintedanib 150mg, and is used for the same indications — IPF, PF-ILD, and SSc-ILD. Brand names vary by manufacturer, but the underlying molecule and its approved uses remain the same; always confirm with your pharmacist which brand your prescription specifies.

3. How much does nintedanib cost?

Nintedanib pricing depends on the brand, strength (100mg vs 150mg), pack size, and manufacturer. Domestic generic brands like Nintepride 15 are typically priced well below the originator brand. Use the Check Price button on this page for current, location-specific pricing rather than relying on a fixed figure, since pharmaceutical prices are revised periodically.

4. How much does nintedanib cost in India?

In India, nintedanib is available through multiple domestic generic manufacturers, which has brought pricing down significantly compared to imported originator brands. Exact price depends on your city, pharmacy, and the specific brand and pack size prescribed. Tap "Check Price" above for the current rate on Nintepride 15.

5. How much does nindanib 100 cost?

"Nindanib" is a common misspelling of Nintedanib. The 100mg strength is typically prescribed as a step-down dose for patients who experience side effects on 150mg twice daily. Pricing for the 100mg strength is generally lower per capsule than 150mg but varies by brand — check with your pharmacist or use our price-check tool for the exact current cost.

6. What is nilotinib 150 tablet used for?

Nilotinib is a different medicine from Nintedanib, despite the similar-sounding name. Nilotinib is a BCR-ABL tyrosine kinase inhibitor used to treat Chronic Myeloid Leukemia (CML), not pulmonary fibrosis. If your prescription says "Nintedanib," do not substitute it with Nilotinib — always confirm the exact drug name with your doctor or pharmacist before purchase.

7. What is the price of nintedanib 150 in India?

The price of Nintedanib 150mg in India varies by brand — domestic generics like Nintepride 15 are generally priced more accessibly than the originator brand. Because pricing is updated periodically and can differ by region, we recommend checking live pricing via the Check Price button rather than a fixed number quoted online.

8. How much does nintedanib 150 mg cost?

The cost of a Nintedanib 150mg pack depends on the brand you choose, the pack size (for example, a 10-capsule pack), and your pharmacy. Because Nintepride 15 is a prescription (Schedule H) medicine, pricing is also subject to standard pharmaceutical retail regulations. Use the Check Price link on this page for the most current figure.

9. What is NINTEPRIDE 15 used for?

Nintepride 15, manufactured by Steris Healthcare Pvt. Ltd., contains Nintedanib 150mg and is prescribed for Idiopathic Pulmonary Fibrosis, progressive fibrosing ILD, and systemic sclerosis-associated ILD, helping to slow the rate of lung function decline in these conditions.

10. How is Nintepride 15 different from the originator brand of Nintedanib?

Nintepride 15 contains the same active molecule, Nintedanib 150mg, and is manufactured to the same pharmacopoeial standards under WHO-GMP and ISO certification. The main practical differences are brand name, manufacturer, and price — generic versions are typically more affordable while delivering the same active ingredient and dose.

11. Can nintedanib cure pulmonary fibrosis?

No. Nintedanib does not reverse or cure existing lung scarring. Its clinically proven role is to slow the rate at which lung function declines over time, which can help preserve breathing capacity and quality of life for longer. It works best as part of a broader care plan that may include pulmonary rehabilitation and regular monitoring.

12. What are the side effects of nintedanib 150 mg?

The most common side effect is diarrhea, followed by nausea, reduced appetite, and mild liver enzyme elevation. Less commonly, it can cause more serious effects like liver injury, gastrointestinal perforation, or blood clotting events — which is why regular liver function monitoring is part of standard treatment with this medicine.

13. How should I take Nintepride 15 capsules?

Take one capsule (150mg) twice daily, roughly 12 hours apart, swallowed whole with food and a full glass of water. Taking it with meals helps reduce stomach-related side effects like nausea and diarrhea. Do not crush or open the capsule.

14. Can nintedanib be taken with food?

Yes — in fact, it's recommended. Taking Nintepride 15 with food helps reduce the gastrointestinal side effects, particularly nausea, that some patients experience when the medicine is taken on an empty stomach.

15. Is nintedanib safe for long-term use?

Nintedanib is designed for long-term daily use in chronic fibrosing lung conditions, and clinical trial data supports extended use under medical supervision. Long-term safety depends on regular liver function monitoring and prompt reporting of any new symptoms to your doctor, who may adjust your dose over time.

16. What happens if I miss a dose of Nintepride 15?

If you miss a dose, simply skip it and take your next dose at the regular scheduled time. Do not take a double dose to make up for the one you missed, as this can increase the risk of side effects like diarrhea and nausea.

17. Is a prescription required to buy Nintepride 15?

Yes. Nintepride 15 (Nintedanib 150mg) is a Schedule H prescription-only medicine in India. It cannot be legally dispensed without a valid prescription from a registered doctor, typically a pulmonologist, rheumatologist, or oncologist.

18. Can nintedanib be used during pregnancy?

No. Nintedanib is not recommended during pregnancy, as it may cause harm to a developing fetus. Women of childbearing potential should use effective contraception while on this medicine and for at least three months after stopping treatment. Discuss family planning openly with your doctor before starting therapy.